I believe that diarrhea can cause an elevation in Prograf level. Taking Prograf with food can decrease absorption and result in a lower Prograf level. This is even more pronounced if you take it with fatty food. If Prograf doesn't upset your stomach it is best taken about 1 hour before eating - on an empty stomach.
The range on my labs sheet is 4 - 16 so you are well within range.
hi to everybody! just wanna ask, my husband latest result of prograf test is 6.5, unlike the previous which is 2.5 only, i donno if it is normal or high level? he is taking prgraf 1mg. 1 in the morning and 1 in the evening. He is now 6 months post transplant.
Thanks for your time my God bless us all.
what role would pot play in one's lab results? does it affect the liver enzymes or the blood profiles? any known effects when used with todays post transplant drugs?
thanks.
My daughter is 1 year post transplant she has had many issues with her LFTs and EBV has always been positive last labs draw it was 175,000 her prograf level was a little high also. I'm concerned about some of her labs well really I dont understand them, Here they are!
RBC- low
Hemoglobin- low
Hematocrit-low
MCV-low
MCH-low
Eosinophil- low
Lymphocyte 2.2 x 1000 ???
Anisocytosis- slight
Microcytosis-moderate
Platelet Morphology-normal
What do all these mean??
If i lower my prograf lower than 6.5 through rate i start getting discomfort right side .i am having cognitive issues on prograf that are getting very hard to live with, seems like it got alot worse after my last of three mri with contrast in two years. was hospitalized two days after last contrast exsposure white blood count went to1000, headach, fever urine got exstremly foamy, severe itching ,tighting and rashd eveloped on lower legs two weeks after.
What are the purported effects on tacrolimus? Has there already been a trial or test? Once a transplant patient's biopsy and lab numbers clearly show him heading down the road to fibrosis and cirrohsis, would it make sense to push for trying the new drugs at least the approved ones for non-transplant such as teleprevir and bocepavir? Otherwise the patient is looking at another transplant which would seem to be quite a negative option.
I have tried benedryl which does not help. The antirejection drug I am on is Prograf. The sensation that I experience is like mosquitos biting or pins pricking. I was referred to a dermatologist that did nothing. Do you have any suggestions as to why I am experiencing this and if this will pass. I also wonder if I should consult with either a allergist or neurologist.
My current dose is Prograf 3 mg AM/ Prograf 3 mg PM and Rapamune 4 mg AM. The intent is to convert me to 100% Rapamune because of the nephro-toxicity of the Prograf and my young age and because of the anti-cancer properties of Rapamune. Data, while horribly limited, has shown Rapamune's anti-cancer properties have had success against vascular tumors such as mine so EHE, in this case chronic, is part of the cancers Rapamune affects (some cancers it has no effect).
I went into rejection twice in the hospital and because of this my transplant team saw it best to put me on 5mg of prograf twice a day as well as 4 mg of rapimune, which by the way was off label and i had to sign a release form for. Just within the past 2 months they lowerd my dosage of rapimune to 2mg but kept the prograf the same. My question to you is exactly how suppressed is my immune system?
One week later she had the tests done again. The test result shows that her TLC has not moved an inch and is still at 2.8. My father is like panicked (he has always been a bit nervous personality anyway). The doctor - does he suspect virus infection, I am not sure - prescribed a blood test, result of which comes out after a week or so. Is this situation - TLC at 2.8 for two weeks now despite CellCept being reduced to Nil mg - is so serious a problem as to cause worry?
I am 6 years post liver transplant from genotype 3 Hep C. My doctors want to start treatment to clear the virus. I take Prograf for the liver transplant and I know Naragenin affects the Prograf levels. My question is if during treatment I also took Naragenin and my prograf levels were closely watched and adjusted for the Naragenin effects, wouldn't I have a better chance of clearing the virus.
My history: liver transplant 1 year ago, had 2 moderate rejections and 1 mild since transplant. At present time having moderate rejection, recently had one portal stent and 8 Bilary ERCP's to remove stones and sludge and had stenting done, and at the present time there are no blockages. Was on Rapamune (5mg a day) prior to hernia surgery and then week before hernia surgery was put on Prograf (4mg a day) and taken off the Rapamune. I have been on Progaf since hernia surgery (8 weeks ago).
If suppressants are at the correct trouph levels, say, Prograf and Rapamycin, what are the next steps - switch suppressants, treat?
i think all of the medications need to be increased further and maybe the prograf dose can be decreased somewhat. if the HTN is refractory then the docs may also need to look for secondary causes such as renal artery stenosis.
t understand the relationship between treatment and Prograf dose. It sounds logical to think that the higher the Prograf dose the less likely TX will be successful and, at the extreme, I think that's probably true. But, whether 3 mg per day or 6 mg Prograf per day makes any difference is a question I cannot answer.
When I treated there was a reluctance to dose the way a non-transplant patient would have been dosed and that can be and, in my case, was problematic.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
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