plavix trial

Lately, there have many posts related to the duration of plavix and it seems patients are given plavix for a long period of time. It has been my understanding from what I have read and my experience, plavix is recommended for individuals that have a drug eluding stent to help prevent clots for up to a year. That has been my experience. DES when compared to bare metal stent implants have an increase of clots and restenosis for a period of one year...

In the CAPRIE trial, clopidogrel (plavix) was equivalent to aspirin for patients with a recent (but not acute) MI. Some subgroups of patients with cardiovascular disease in this trial seemed to benefit more from clopidogrel than from aspirin: those with a history of bypass surgery, a prior stroke or MI, arterial disease in two or more areas, diabetes, or high cholesterol. Clopidogrel may be a reasonable choice for these patients.

I understand you being on Plavix for your heart, and you should remain on it. But I am very surprised to hear that your husband is still on Coumadin for a clot 3 years ago. Is this clot the only reason he takes it? My daughter had a blood clot due to a very serious car accident, but once her injuries healed, she no longer had to take anything. He needs to address this with his doctor, and ask why he still has to take it.

Taking Plavix indicates you have drug eluding stents. The a drug-eluting stents (DES) basically have a special drug that delivers the agent right at the site of the injury to the artery and prevents much of the scar tissue from recurring. Compared to the alternative bare metal stent and it is known that the likelihood of the arteries re-narrowing after drug-eluting stents are much less than after bare metal stents.

It seems plavix helps reduce the risk for clots at implant site, and after a year the risk of clots is less than the risk of excessive bleeding with plavix. After a year discontinued plavix and remain on a baby aspirin. Several months ago after some dental work there was excessive bleeding for hours on a baby aspirin...so I'm not cool with large doses of anti-platelet meds. Warfarin can cause very serious (possibly fatal) bleeding.

And then a preliminary analysis of data from the COGENT trial, a trial dedicated to specifically examining clopidogrel with a PPI vs placebo, fails to suggest even the slightest signal of a negative interaction. For the FDA to then strengthen the warning of a interaction is baffling, to say the least." Also, IIRC the AHA and ACC haven't advised against the combination.

Thank you for your answers and god bless you all! I don't take anything except asprin. I took Plavix only one months after stent then gave up. When I take nitro I get headachce that's why I don't take it. However, when I have shortness of breath I have stiff neck. Maybe is it due to tromb. I just want to know the reson after that want to take durgs. Still my diagnose is not much clear to me.

I have been taking Plavix 75 MG daily. A recent plavix test showed it was not helping. Now my PA has me on 150 MG Plavix. I really bleed when scratched now. Should I take the Plavix test again to see if the increased dossage is working? I am also taking 325 mg asprin.

Did your doctor determine that you risk was so high that he wanted you on Plavix long term, these are the only circumstances that using Plavix long term would be.

My heart Dr will not let me go off the plavix and my surgeon will not do the surgery while on plavix. What happens in a situation like this?. I am between a rock and a hard place. If neither Dr gives in what do I do? If I have an attack and end up in the ER wouldn't they have to do emergency sugery?. Does this mean that anyone on plavix can never have surgery unless it's an ermergency. What is your opinion on going off plavix temporarily for surgery. I would welcome anyones advice.

I had an MI in '05, and had a RCA stent placed. I was on plavix apox. 4 yrs because of family hx and my paranoia of another MI. I recently have been experiencing tingling and numbness in my hands upon awaking and have noticed small spider veins appearing on my thighs. I am a nurse on a MedSurg unit. I am concerned that my stent is becoming occulded. My doctor took me off plavix Jan'10 and kept me on 325 Aspirin.

My cardiologist would not let my dentist allow me to stop taking Plavix for even 5 days to alleviate my pain due to a cavity .The dentist is bent upon my discontinuing Plavix to enable filling of the cavity or do root canal to solve the problem.

She was given platelet went up then down again Can plavix make it worse and will her platelet revert back to normal

I HAVE 3STENTS AND i can't come off Plavix.. I had a colonoscopy this morning for diagnostic reasons and I am full of polops,but they couldnt take any out while I am on Plavix...Last time I went off plavix for 2 days I had my 2nd heartattack so I CAN NOT GO OFF OF IT..I hac surgery to remove a salivary gland and had to stay overnight for obsevation and everything turned out all right.. Is there anyway to remove these polops while on Plavix ?

My Cardio wants me on the plavix indefintely, so will not give me the ok to stop the plavix for 10 days and the Surgeon will not do the procedure with me on the plavix. I'm in a no win situation. My symptoms are not that severe yet, Does anyone have any suggestions or advice. Should I try another Cardio for a 2nd opinion or is there someone that I can complain to so these dr's will get together to corrdinate something.

Structual collapse of a stent would indicate an improper size or defect. I discontinued plavix after year, and I have never heard of plavix associated with a collapsed stent! There may be a misunderstanding.

I have read so often that you should not take Plavix and aspirin, but it seems to also be common to prescribe both plavix and aspirin in certain situations. I am worried and confused. Thanks.

I have a high deductibule ins policy I have found several web sights that offer generic Plavix or [clopidogrel] that is suginifantly cheeper than brand name Plavix Will the generic work as good as plavix? Or is it just a plasebo?

I think plavix is very important for CAD sufferers. The half life of plavix is short anyway, so if it came to some emergency, it wouldn't take long for the effect to wear off.

Will long term use of Plavix cause internal bleeding? This discussion is related to <a href='/posts/show/250846'>Long Term Plavix Side Effects?</a>.

Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.

a peck and a hug around the neck, boy that brings back some memories, now about the indigestion, that would depend on how long you have been on the Plavix, and also besides the obvious blood thinning action of Plavix what brought you to be on it? I recieved a heart stent in 09' and they put me on it then along with the aspirin. This year my doctor said that I could now go back on prilosec. The gov.

Please note that the article mention plavix as used as "prevention of stroke" here we are speaking of Plavix to avoid restenosis and clots in the case that you have medical stents implanted. The situation is quite different.

Both my mom and dad were on plavix. When my mom needed surgery, she was taken of the plavix for awhile. However, when my dad needed surgery, he was kept on it. Your doctors need to make that decision. Good Luck! Wishing you well, and wishing you enough...

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