I've just been switched from Fentanyl 25mcg every 48 hrs to Oxymorphone 10mg every 12hrs. I feel way worse (pain) & was wondering if anyone knows what the equivalence is between the 2. I have a feeling I've just been decreased in pain relief. My dr & the pharmacist told me to wait a few days to "feel it's working" & in the meantime I'm in excruciating pain. Can anyone help with what I can do here? Btw...
I am going to try replacing that for a short time with a Fentanyl Patch to see if I have any improvement in Pain Mgmt. I am just wondering what regimen I should use to safely do this. For example. Is it as easy as waiting 12 hrs. after my last Opana ER and then apply the patch (it's a 3 day patch) then take another ER once the 3 days has expired? Please let me know as I am going to try this either way. Thank you.
I dont see much about it in these posts but I have been taking oxymorphone(OPANA) for FBS.I have been addicted to Meth cocaine and alcohol in the past but have been free from those chains for 10 years.My disease has resurfaced with this Opana though.I have cut my intake from 20 mg a day to 10 mg a day for the past three days.I have been blessed to avoid the terrible sickness of opiate withdrawl that I went through last year with this **** when I went CT off of it.
hydromorphone was detected in patients treated with high-dose morphine. The ratio of hydromorphone to morphine ranged from 0.2 to 2.2%. Oxymorphone was not detected in any specimen from high-dose morphine or high-dose hydromorphone patients. The authors conclude, based on these data, that oxymorphone is not a metabolite of morphine or hydromorphone.
I wish I had better answers for you. I am not super knowledgeable in Chemistry. This was not imperative some years ago - so I am learning.
have been clean for months I have been taking suboxon 2mg twice a day and an antidepresent every day I see my doctor once a week and drop urine every time on the initial test I have been clean but when it comes up on the computer he says that i have oxymorphone in my system, this just cant be what could cause this.
If you are taking the meds exactly as prescribed, typically most PM offices use an in office positive or negative, and then send the test out for confirmatory testing, which looks at actual levels .
It would be highly unlikely that gc/ms testing would be a false negative. It measures the metabolites of the medications in the body.
Is there a chart that I can use to convert fentanyl patch strength to the Opana Er strength?
I feel I should jump in on this thread.
Opana ER is extended release oxymorphone. It is most powerful opioid pain reliever in pill form on the market today based solely on pharmacology. I was on this medication from Jan-Apr of this year at 30 mg bid (i.e., twice a day).
5 mg of Opana ER is equivalent to 10 mg of oxycodone. Oxycodone is the active ingredient in Percocet.
If the new oxycontin OP worked very well on your pain, I highly recommend talking to your doctor about Opana ER. It is oxymorphone and it is strongest pain medication available in pill form based on pharmacology. The oxycodone in Oxycontin is metabolized by the liver into oxymorphone. Therefore, the Opana ER would be a drug that is very comparable to the Oxycontin, only twice as strong.
I’ve been taking 5mg oxymorphone extended release pills for 8 years. I recently had to switch primary care doctors because mine moved away. The first urine drug test I was asked to do was last Friday and they called today and said the drug didn’t show up in my system, and dropped me as a patient. I should start withdrawals tomorrow & I’m scared out of my mind. I’ve never failed a drug test, asked for an early refill, nothing like that.
Be careful as you will build a tolerence to any opiates you take. Take them sparingly.
Assuming you are converting from extended release to extended release or immediate release to immediate release then:
1mg of oxymorphone is equal to about 2mg of oxycodone
1mg of oxycodone is equal to about .5 mg of oxymorphone
Oxycodone is half as potent, mg for mg.
Incivek is new enough that no one knew to warn me of this, but it quickly became obvious to me that Incivek interacted with my narcotic painkillers (oxymorphone was the specific drug in use at that point) to greatly increase my blood levels of the narcotic. While on Incivek I could have overdosed had I not been especially careful. I had to halve my narcotic dose for the duration of the Invivek phase of treatment.
I am going through serious withdrawal. I suffer chronic back and hip pain and my doctor can't seem to find the source of the pain. So I started to medicate myself. I started off with oxy 30s. then I started dating a guy who also is in chronic pain and when I would start getting "sick" from not being able to get the 30s he gave he some of his oxymorphone, opana, and I don't want to continue taking his meds anymore.
Oxycodone is metabolized by the liver into oxymorphone. Oxymorphone is about 2 times stronger than oxycodone based on pharmacology. When I was first switched to Opana, the drowsiness and tiredness were unreal! It was a real struggle for me at first and I also have a desk job. However, the sedation effects only lasted for a month at the most. Now I don't get sedated anymore and in fact I am more alert than I was on Morphine.
I believe it would show up if being tested for both opioids and synthetic opioids. The reason why you tested positive for oxymorphone is because oxycodone which is found in percocet can produce oxymorphone when it is metabolized in the liver. The codeine-hydrocodone group and morphinans can also produce oxymorphone.
Stands to reason that:
2 x 5mg Percocet = 1 x 10mg Oxycontin
Don't quote me on that though. I know Percocet has both Oxymorphone AND Acetaminophen in it, and Oxycontin has Oxymorphone only. I'm not certain what the Acetaminophen brings to the table as far as drug-interactions go, but your statement that the Perc and the Oxy are the same (2x5mg vs. 1x10mg) sounds about right.
Maybe someone in the Pain-Management Community would know.
Hi Snobuny,
Welcome to our Pain Management Forum. You've asked a good question and although it may seem straight forward there's a lot to be considered.
Oxymorphone is seven times stronger then morphine while hydromorphone is five times stronger than morphine. They are in the same synthetic family of drugs. Although on "paper" Oxymorphone is more potent then Hydromorphone that doesn't necessarily mean that one is more effective then the other.
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