I've just been switched from Fentanyl 25mcg every 48 hrs to Oxymorphone 10mg every 12hrs. I feel way worse (pain) & was wondering if anyone knows what the equivalence is between the 2. I have a feeling I've just been decreased in pain relief. My dr & the pharmacist told me to wait a few days to "feel it's working" & in the meantime I'm in excruciating pain. Can anyone help with what I can do here? Btw...
I dont see much about it in these posts but I have been taking oxymorphone(OPANA) for FBS.I have been addicted to Meth cocaine and alcohol in the past but have been free from those chains for 10 years.My disease has resurfaced with this Opana though.I have cut my intake from 20 mg a day to 10 mg a day for the past three days.I have been blessed to avoid the terrible sickness of opiate withdrawl that I went through last year with this **** when I went CT off of it.
hydromorphone was detected in patients treated with high-dose morphine. The ratio of hydromorphone to morphine ranged from 0.2 to 2.2%. Oxymorphone was not detected in any specimen from high-dose morphine or high-dose hydromorphone patients. The authors conclude, based on these data, that oxymorphone is not a metabolite of morphine or hydromorphone.
I wish I had better answers for you. I am not super knowledgeable in Chemistry. This was not imperative some years ago - so I am learning.
I’ve been taking 5mg oxymorphone extended release pills for 8 years. I recently had to switch primary care doctors because mine moved away. The first urine drug test I was asked to do was last Friday and they called today and said the drug didn’t show up in my system, and dropped me as a patient. I should start withdrawals tomorrow & I’m scared out of my mind. I’ve never failed a drug test, asked for an early refill, nothing like that.
Be careful as you will build a tolerence to any opiates you take. Take them sparingly.
Assuming you are converting from extended release to extended release or immediate release to immediate release then:
1mg of oxymorphone is equal to about 2mg of oxycodone
1mg of oxycodone is equal to about .5 mg of oxymorphone
Oxycodone is half as potent, mg for mg.
I am going through serious withdrawal. I suffer chronic back and hip pain and my doctor can't seem to find the source of the pain. So I started to medicate myself. I started off with oxy 30s. then I started dating a guy who also is in chronic pain and when I would start getting "sick" from not being able to get the 30s he gave he some of his oxymorphone, opana, and I don't want to continue taking his meds anymore.
Oxycodone is metabolized by the liver into oxymorphone. Oxymorphone is about 2 times stronger than oxycodone based on pharmacology. When I was first switched to Opana, the drowsiness and tiredness were unreal! It was a real struggle for me at first and I also have a desk job. However, the sedation effects only lasted for a month at the most. Now I don't get sedated anymore and in fact I am more alert than I was on Morphine.
I believe it would show up if being tested for both opioids and synthetic opioids. The reason why you tested positive for oxymorphone is because oxycodone which is found in percocet can produce oxymorphone when it is metabolized in the liver. The codeine-hydrocodone group and morphinans can also produce oxymorphone.
Stands to reason that:
2 x 5mg Percocet = 1 x 10mg Oxycontin
Don't quote me on that though. I know Percocet has both Oxymorphone AND Acetaminophen in it, and Oxycontin has Oxymorphone only. I'm not certain what the Acetaminophen brings to the table as far as drug-interactions go, but your statement that the Perc and the Oxy are the same (2x5mg vs. 1x10mg) sounds about right.
Maybe someone in the Pain-Management Community would know.
Did the office just do an in office screen or did they send the urine out for testing? Opana is oxymorphone, which is a synthetic opioid, not a traditional opiate. In office screens have a cut off threshold, which is different depending on the test used. The cut off threshold determines what levels must be present for a positive or negative.
Hi Snobuny,
Welcome to our Pain Management Forum. You've asked a good question and although it may seem straight forward there's a lot to be considered.
Oxymorphone is seven times stronger then morphine while hydromorphone is five times stronger than morphine. They are in the same synthetic family of drugs. Although on "paper" Oxymorphone is more potent then Hydromorphone that doesn't necessarily mean that one is more effective then the other.
Opana ER is oxymorphone in extended release form. Oxymorphone is the STRONGEST opioid medication in pill form available in the United States soley for pain management. Therefore, short answer is yes...Opana ER is stronger than oxycodone mg to mg. For example, 1 mg of oxymorphone is stronger than 1 mg of oxycodone...to be precise, oxymorphone is approx. 2 times stronger than oxycodone.
have been clean for months I have been taking suboxon 2mg twice a day and an antidepresent every day I see my doctor once a week and drop urine every time on the initial test I have been clean but when it comes up on the computer he says that i have oxymorphone in my system, this just cant be what could cause this.
I have DDD and mild spinal stenosis along with a lot of other imperfections of the spine. It has affected NY back so much I haven't been able to hold down a job where U have to stand or do physical work since age 30. I am 47 now and now a nerve in my spine is impinged and causing me horrific knee and foot pain. I wajecup in pain in the middle of sleep. I'm on 5mgs 3x's a day and oxymorphone 2x's a day. It help about 25 to 30%. This is very inhumane.
The web site also explains that for some uknown reason that Oxycodone can metabolize into Oxymorphone. In a study, 93% percent of patients came up positive for Oxymorphone when in fact they were only taking Oxycone. WOW...........
If the new oxycontin OP worked very well on your pain, I highly recommend talking to your doctor about Opana ER. It is oxymorphone and it is strongest pain medication available in pill form based on pharmacology. The oxycodone in Oxycontin is metabolized by the liver into oxymorphone. Therefore, the Opana ER would be a drug that is very comparable to the Oxycontin, only twice as strong.
She indicated that for patients that take 100mg or more per day of Oxycodone - that 93% of the time the urine test comes back positive for Oxymorphone, which of course is what is in Opana. She studied a whole bunch of pain mgmt patients and this is what she found.
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