Please note Tenofovir is principally cleared through the kidney and dosing adjustments due to renal impairment have not been clinically tested.
The followings are extracts from the label information for Tenofovir:
2.3 Dose Adjustment for Renal Impairment in Adults
Significantly increased drug exposures occurred when VIREAD was administered to subjects with moderate to severe renal impairment [See Clinical Pharmacology (12.3)].
I am not aware that impaired renal function precludes treatment for HCV. I have read that kidney disease is a negative predictor of SVR but, so too are a lot of conditions yet people have overcome them. I have seen articles which discuss the plasma levels of ribavirin with renal impaired patients. The suggestion is that rather than weight base dose these patients the dose should be arrived at by considering GFR (glomerular filtration rate).
This is from Clinical Care Options @ http://tiny.
Hello my 12 year old was taking omnicef for a ear infection and 10 days into it she got hives all over her body and they come and go and really ichy do you think it's from the Omnicef?
By "AGE" I'm assuming you mean a persons age in years. I don't believe age has anything to do with Janumet's "effectiveness" but age has a larger role with renal function. To make it clear for other readers, Janumet is combination of two drugs; Sitagiptin and Metformin.
This a brief from the Merck web site - makers of Janumet - Section 8.5 - Geriatric Use JANUMET.
I also have kidney damage from a bout of high blood pressure 4 years ago, and I am a frequent kidney stone former, so I am being watched carefully by a nephrologist too. I have renal panels frequently too. I was wondering if any of this could increase my stone risk. I was reading about the cytomel and stones. The nephrologist wants me to remain on the synthroid and cytomel.
I think it depends on some individual factors, particularly renal clearance of the drug. I found this information in the drug reference:
According to the manufacturer's tests, the drug reaches maximum serum levels between 15 and 44 hours after subcutaneous injection of a single dose. The mean elimination half-life is 22 to 60 hours (mean = 40 hours). So, I would expect that after 7 days (4.2 half-lifes) that the concentration would be about 5.5% (0.5^4.2) of the maximum levels.
I have had a round of Avelox a few weeks ago and recently Omnicef 600mg/day for 10 days and still have discharge. Question,
wouldn't these antibiotics be affective against NGU, Chlamydia or Gonnorrhea? Thanks for the help.
Glomerular filtration rate or its approximation of the creatinine clearance are measured whenever renal disease is suspected or careful dosing of nephrotoxic drugs is required. The normal ranges of GFR, adjusted for body surface area for males is 70 ± 14 mL/min/m2 (56-84) . Risk factors for kidney disease include diabetes, high blood pressure, family history and older age.
Take care and keep us posted.
Thank you! I tested positive for Lyme and was clinically diagnosed with bartonella last weekend (I had the rashes). My LLMD started me on omnicef and rifampin. Unfortunalty I'm allergic to alot of antibiotics. It's good to hear that your tinnitus went away. I'm just scared of the antibiotics making it worse. 2 years is a long time! Are most of your symptoms resolved?
Hi all, wondering if you have come across information indicating that flagyl can treat babesia at the same time it's treating Lyme. I understand it's also a antiparasitic, so not sure if that counts. If anyone knows or has heard their LLMD mention this please let me know. I just took my first dose of Flagyl, keeping my fingers crossed that I see some fantastic results!
About 1 year ago I as given Omnicef for a bacterial infection. After 3 days of tumultuous diarrhea, I finally stopped this drug but not soon enough. Ever since then, I have had stomach problems. It first started out as irregular and often BM’s, and then progressed to
A constant gnawing or burning between my breastbone and navel in addition to erratic BM’s and gas, bloating, and just an overall lousy feeling within the digestive system.
I am on everything except the Cefidinir(Omnicef) bc she is adding that after we add the Septra and sees if it is well tolerated.
There are preferred opiates drugs that are use in patients with liver disease that have shorter half-lives and have less harmful side effects on the renal system. Your liver doctor should be aware of these drugs and be able to determine if you may be able to use them.
With regards to OTC medications, normal recommended doses of acetaminophen can be safely given to patients who suffer from cirrhosis in the short term.
My 4 yr.old son had an allergic reaction to Omnicef. Hives all over and swollen hands, arms and feet. It's been 18 days and still gets a slight case of the hives . Within the last week( 3 times) he's had leg pain(muscel pain) joint pain. He has a hard time walking, usually the next day he can, it lasts anywhere from 12-24 hours. The 3 times he's had the leg pain he's either been swimming or riding a bike, took him to the hospital, blood work, x-rays and urine all came back fine.
But regarding this Vit D , should i need to take along with calcium supllements Or no need? I have renal stones of 0.5mm. Does this have any effect on this?
I took her to her pediatrician that same day where they did a strep test which came back negative, prescribed omnicef and sent us home. The next day her temperature just kept skyrocketing, getting up to 106. That night I took her to the ER at Children's in Dallas where they ran another strep test, mono, flu, and cbc. Her mono, strep, and flu all came back negative. Her white blood count was at 21. They gave her a shot of rocephin, told us to continue the omnicef, sent us home.
If you are stage 3 you can take any analgesic within dosing limits. Your liver function has not been altered by your liver disease yet. If you become stage 4 (cirrhosis) then you will have to modify what drugs you can take because the liver is no longer able to process drugs in a normal manner.
Tramadol is an synthetic opiate and should not be taken for "mild" pain.
Call your local pharmacist. We at MedHelp are not allowed to give out dosing instructions. Your pharmacist will be able to tell you exactly how to dose the medications. If your regular pharmacy is closed on Sunday, call any pharmacist availabe at your local grocery store or drug store such as Walgreens, CVS, or RiteAid.
He was put on amoxil and had an allergic reaction so he has been taking omnicef. The Dr told us this week that the omnicef has not done anything and that he was going to give him a round of antibiotic shots. So far my son has had 2 of the 3 shots. My first question is how quickly do these shots work? My other question is: Is there some underlying problem that is causing these ear infections, something more serious? He has not had any other type of infection i.e.
My child was 1 1/2 months old when she developed a "cold" that consisted of a stuffy nose for about 1 1/2 months. After 2 bouts with antibiotics(amoxicillin & omnicef) it seemed that we were in the clear. Then about 3-4 weeks later she came down with a terrible cold that doesn't seem to want to go away and the doctors said there was nothing they could do for it.
I have swollen eyelids that come and go, almost like hives, but rarely itch. Can be one or several. On omnicef for sinus infection, but doctor doesn't think this is causing it. Before omincef had a sulfer type med that caused swelling in joints, sick stomach, rash, fever. Have been on Omicef 5 days. Started having strange raised bumps for three days that come and go. Will say that two weeks ago had actual hives around eyes and think it was caused from eye cream.
I cannot take Rifampin because it contains Omnicef which I am allergic to, so I should be ok right?
RENAL RISK
TORADOL is CONTRAINDICATED in patients with advanced renal impairment and in patients at risk for renal failure due to volume depletion (see WARNINGS).
RISK OF BLEEDING
TORADOL inhibits platelet function and is, therefore, CONTRAINDICATED in patients with suspected or confirmed cerebrovascular bleeding, patients with hemorrhagic diathesis, incomplete hemostasis and those at high risk of bleeding (see WARNINGS and PRECAUTIONS).
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