Once I had to reduce to 1/2 of Riba because my ANC dropped to 400 and wouldn't come back up. I only did it for a week. I believe it's your ANC that is the driver not only your WBC. But, I know my dr. looked at my platlets & hemoglobin along with the ANC, before determining the reduction. When my WBC was around 1.8 - 1.9, I stayed on full tx.
Thanks for your reply. Its now march 4 th. All seems fine. I feel good again and not so week.
I guess neulasta's route of elimination keeps it's action (like neupogen) around much longer so that there probably would not be a reason for neupogen at that point.
The side effects of the neupogen were more pronounced when I did them after my first tx, just like you said. I think that all the various side effects of the treatment drugs masked the sx of the neup. Seems like I took 3 or 4 shots after I was done, just to boost the WBC. We do what we have to do, don't we.
I take 1/2 dose of Neupogen on Mon, Wed. and Sat. I inject the Pegasus
on Friday. I was given the option of taking the Neupogen on Friday, to avoid 4 days of injections. I decided I rather do 4 days than 2 in one day.
Pegasus and Neupogen can be taken on the same day.
My doctor has assured me I can just about take it anytime without concern
for tx. I trust his opinion in that he treats medical professionals from around the country.
Neupogen is a very often used rescue drug to help raise whit blood cells. many doctors would do this when the ANC gets to 500 and some would let it fall to 300 or so.
often tho ,,it will drop and then stabilize or even rise some. Good idea to get the Neupogen at the ready just in case that doesn"t happen and it continues to drop.
m interested in hearing from anybody who has had similar symptoms, or a similar course of action before getting a diagnosis. I have never really heard of tinnitis or vertigo being symptoms of MS, and those are the main reasons I even started pursuing medical help to begin with. The doctors have ruled out some explanations (like the acoustic neuroma), but there are still other possibilities on the table (Meniere's disease, or even high blood pressure for example).
It kind of sounds like a form of Action tremors, but I have to agree with mkh9.
as my doctor said, and it was either take Neupogen along with Pegasys and Ribavirin or stop treatment all together. I have been clear of the virus since 11/08, but have had a slew of issues that are hindering my life. I was just wondering what others who took Neupogen experienced post treatment, if anything.
Thanks in advance!!!
I recall that when I started the neulasta (pegylated form of neupogen that stays in system longer), I was required to come back next day for blood draws to see if I responded to it and how well I responded. Towards the end of TX, the effects (holding my neuts above danger level) lasted a shorter time, so I guess the blood helper drugs may get less effective but they did still work.
The neupogen (or neulasta) works overnight. Other posters (was it nygirl?
m on the trial which forces a dosage reduction of the INF at 1.5. I have been on interferon reductions of 25% for 6 of the past 8 weeks and getting very worried about that and asked my doctor for neupogen to get me out of this dosage reduction range. He is my favourite aggressive doctor and he said no for various reasons. I was not happy about that, not at all, I see the neupogen as my only option to get all my white counts back up again.. my CD4, my lymphocytes, my ANC..
I just read that a lot of people try NOT to take Neupogen unless it is a necessity due to sx. I am on Neupogen and I take it 3 times a week and have been taking it for 8 mos. now.
Does anyone know exactly why people/anyone would want to NOT take Neupogen?
Your answers may provide some insight for me and my sx's.
t make an issue out of low ANC. In my total of 134 weeks of tx i never once did neupogen and mine got below .5 at times.... When my grandson was in junior bowling league i brought it up being i was surrounded by at least 50 little rug rats in a bowling alley every Saturday... He thought i was more app to need Tylenol for the headache i was going to get. And he was right that was the only thing it caused me. Never caught anything.
they caught swine flue) from having a doc who left them on high dose of interferon even while having low WBC.
low blood count started neupogen injections to build up white blood cell count so I can have chemotherapy, can I drink beer with this?
So the doc finally agreed to a neupogen shot, after many delayed shots of pegasys. I was supposed to do a shot tuesday, however got bloodwork done today and anc is 620, Doc says to take neupogen tonight (I did, the neupogen is 300mcg, im ~130lbs) and get more bloodwork done on thursday, and then he'll call friday with whether or not to take the shot or not. So here I am, waiting, again. Arggg!
4th is my last of pegaferion yeah,then nov.11 the last of rivoverion. you know when i had my 1st shot of peg. 3.5 hours later it was pretty painful,im not a weeny i can handle pain but this is a pain i could do without. so from then on i took childrens ibpro. 1hour before no more pain with that so if i have to cont. the neuprogen maybe i should do the same with this---thank you !
at one point, i was on neupogen 2X weekly, but everyone is different. some people get it at the beginning of tx, some at the end, some all the way through, some don't get it at all.
i get best results when i give it on sunday after my friday peg cause it allows my whites to grow before next friday's shots if that makes any sense. and make sure you let it warm a bit before you inject or else it will sting! overall, not too bad, has become a routine for me now.
good luck!
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