Once I had to reduce to 1/2 of Riba because my ANC dropped to 400 and wouldn't come back up. I only did it for a week. I believe it's your ANC that is the driver not only your WBC. But, I know my dr. looked at my platlets & hemoglobin along with the ANC, before determining the reduction. When my WBC was around 1.8 - 1.9, I stayed on full tx.
I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
Thanks for your reply. Its now march 4 th. All seems fine. I feel good again and not so week.
I guess neulasta's route of elimination keeps it's action (like neupogen) around much longer so that there probably would not be a reason for neupogen at that point.
The mechanism of action of Campral® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.
http://www.nasdaq.
The side effects of the neupogen were more pronounced when I did them after my first tx, just like you said. I think that all the various side effects of the treatment drugs masked the sx of the neup. Seems like I took 3 or 4 shots after I was done, just to boost the WBC. We do what we have to do, don't we.
Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
I take 1/2 dose of Neupogen on Mon, Wed. and Sat. I inject the Pegasus
on Friday. I was given the option of taking the Neupogen on Friday, to avoid 4 days of injections. I decided I rather do 4 days than 2 in one day.
Pegasus and Neupogen can be taken on the same day.
My doctor has assured me I can just about take it anytime without concern
for tx. I trust his opinion in that he treats medical professionals from around the country.
HIV is transmitted by;
Unprotected penetrative anal and/or vaginal sex
Sharing works with other IV drug users
Mother to child
You never had an exposure.
Neupogen is a very often used rescue drug to help raise whit blood cells. many doctors would do this when the ANC gets to 500 and some would let it fall to 300 or so.
often tho ,,it will drop and then stabilize or even rise some. Good idea to get the Neupogen at the ready just in case that doesn"t happen and it continues to drop.
Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.
as my doctor said, and it was either take Neupogen along with Pegasys and Ribavirin or stop treatment all together. I have been clear of the virus since 11/08, but have had a slew of issues that are hindering my life. I was just wondering what others who took Neupogen experienced post treatment, if anything.
Thanks in advance!!!
I recall that when I started the neulasta (pegylated form of neupogen that stays in system longer), I was required to come back next day for blood draws to see if I responded to it and how well I responded. Towards the end of TX, the effects (holding my neuts above danger level) lasted a shorter time, so I guess the blood helper drugs may get less effective but they did still work.
The neupogen (or neulasta) works overnight. Other posters (was it nygirl?
http://www.medscape.com/viewarticle/578705
Ribavirin improves early responses to peginterferon through improved interferon signaling.
Gastroenterology. 2010 Jul;139
The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of interferon-stimulated genes. We evaluated viral kinetics, serum cytokine expression, and viral mutagenesis during early stages of peginterferon therapy with and without ribavirin.
Seeing an orthodontist is advised.
m on the trial which forces a dosage reduction of the INF at 1.5. I have been on interferon reductions of 25% for 6 of the past 8 weeks and getting very worried about that and asked my doctor for neupogen to get me out of this dosage reduction range. He is my favourite aggressive doctor and he said no for various reasons. I was not happy about that, not at all, I see the neupogen as my only option to get all my white counts back up again.. my CD4, my lymphocytes, my ANC..
I just read that a lot of people try NOT to take Neupogen unless it is a necessity due to sx. I am on Neupogen and I take it 3 times a week and have been taking it for 8 mos. now.
Does anyone know exactly why people/anyone would want to NOT take Neupogen?
Your answers may provide some insight for me and my sx's.
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