Maybe your lymphoctyes are low because of the infection? Not sure if one day is going to make much of a difference in numbers. If you ANC is OK -- above 500 -- why take Neupogen? You've mentioned that your trial guidelines appear somewhat flexible. Use that to your advantage and present your tx team with studies and arguments to continue tx on full dosage and without Neupogen. Isn't that what Dr. D. suggested in the professional forum?
The most common are injectable meds Neupogen and Neulasta. Neulasta is the pegylated version of Neupogen. Referred to as colony stimulating factors they are both effective in raising the absolute neutrophil count, which is the usually the focus component of the white cell count. Generally speaking, these meds will temporarily raise the counts and then the treament meds effects will usually repeat. So, the use of Neup and Neu will probably not be one-time events.
have been receiving aranesp and neupogen for the last 8 weeks to help with my anemia while going through treatment. My wbc, rbc, hemoglobin and ANC held steady for the first few weeks, then started increasing and now as of last week took a decline. My wbc's went from 3.4 to 2.3, rbc's went from 2.9 to 2.7, hemo went from 10 to 9.33 and ANC went from 1770 to 930 all in one week. Is that normal and why would that happen when they were on the incline?
Yes, Dr D thought my response was very fast. I didn't realize that most people took 2 - 6 weeks. If that is the case then I agree with your entire conclusion.
Related, is the question -- Was it really necessary to reduce to the Peg in the first place, as many inexperienced doctors pull (or reduce) the Peg much too early instead of either using more relaxed ANC (fraction of his white cells) guidelines, or starting Neupogen right away. Also, in many cases only the Peg is stopped (or reduced with low WBC and not the Riba.
) for dosing guidelines, but be sure to check with a licensed physician. Also check ilads (dot) com for Dr Burrascano's treatment guidelines. There may be useful information there. Also did you try searching something like "lyme disease iv rocephin dose"? Checking with an MD is important before proceeding with any such treatment. No one here is medically trained to my knowledge.
Table 3, Table 4, Table 5, and Table 6 provide guidelines for dose modifications and discontinuation of PEGASYS/COPEGUS based on laboratory
abnormalities, patient’s depression status, and cardiac status.
Adult Patients
When dose modification of PEGASYS is required for adverse reactions (clinical and/or laboratory), initial dose reduction to 135 mcg (which is 0.75 mL for the vials or adjustment to the corresponding graduation mark for
the prefilled syringes) is recommended.
Hi there. We don't allow dosing guidelines of medication to be given here. You should check with your doctor for guidance.
Sounds like both of you need to check with your doctor about what we fondly call rescue drugs. Neupogen boosts white blood cell production and Procrit boosts red blood cell production.
Net - throughout my 56 weeks of treatment my WBC was always in the 1s and I rarely got sick. The lab that most of the doctors watch for is the absolute neutrophils. Neutrophils are a type of white blood cell necessary to fight infection. When it is low, you are open to a multitude of infections,.
The one thing I learned from both his old posts as well as OHs is how tricky the timing can be with Neupogen. I knew out the outset to be vigilant about the timing of my labs and the Neupogen dose. Even though this was only weeks ago I see I saved myself some time and discomfort since I knew what to ask and what to look for when I started this med.
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