Narcolepsy treatment hypocretin
Common Questions and Answers about Narcolepsy treatment hypocretin
narcolepsy
Emerging treatments being investigated for narcolepsy include hypocretin replacement, hypocretin gene therapy, stem cell transplant, skin temperature manipulation and immunotherapy, but further research is needed to confirm their effectiveness.
So, discuss the various options with your doctor and hope you find a balance.
Hope this helped and do keep us posted.
The combination of this study and my first MSLT nap study produced a perfect pattern for diagnosis of Narcolepsy.
Has there ever been a study to look at the coorelation between the 2 diseases. Would many CFS sufferers be classified narcoleptic if they took the appropriate test? Narcolepsy leads back to hippothalmus and lack of production of hypocretin/orexin(?). Seems like all things lead to hippothalmus. Thank you!
Hi, welcome to the forum. Your history is suggestive of narcolepsy. In this condition there will be excessive daytime sleepiness. In this condition there will be “automatic behavior" such as driving past a highway exit or writing off a page, with no memory of the previous few minutes. Classical narcolepsy constitutes of Hypnagogic hallucinations, Sleep paralysis and Cataplexy (emotionally triggered muscle paralysis resulting in partial or complete collapse).
Hi, welcome to the forum. Your history is suggestive of narcolepsy. In this condition there will be excessive daytime sleepiness. In this condition there will be “automatic behavior" such as driving past a highway exit or writing off a page, with no memory of the previous few minutes. Classical narcolepsy constitutes of Hypnagogic hallucinations, Sleep paralysis and Cataplexy (emotionally triggered muscle paralysis resulting in partial or complete collapse).
What you suffer from is probably narcolepsy, which is a neurological disorder. This is thought to be caused by low protein called hypocretin, which is made in the brain. The symptoms are an urge to sleep especially after meals. Sleep studies and EEG are done to rule out other causes of poor sleep and insomnia. Eating light and frequent meals during the day helps. Also assigning a nap time during the day often helps. You can take a light meal before this.
I have recently been diagnosed with narcolepsy. For years, I have suffered from EDS muscle weakness that has become worse as I have aged (mid-40's). In the beginning, I blamed it all on being single and burning the candle at both ends (20's); then being a new parent (30's) and then being a single mom to a child with narcolepsy and a preteen (now 40's). I was told I have mild cataplexy.
What you suffer from is probably narcolepsy, which is a neurological disorder. This is thought to be caused by low protein called hypocretin, which is made in the brain. The symptoms are an urge to sleep especially after meals. If the symptoms are not very prominent then you may just feel fatigue and a need to lie down. Sleep studies and EEG are done to rule out other causes of poor sleep and insomnia. Eating light and frequent meals during the day helps.
Hi, welcome to the forum. Your history is suggestive of narcolepsy. In this condition there will be excessive daytime sleepiness. But in your case it seems milder form of it. In this condition there will be “automatic behavior" such as driving past a highway exit or writing off a page, with no memory of the previous few minutes. Classical narcolepsy constitutes of Hypnagogic hallucinations, Sleep paralysis and Cataplexy which is not seen in your case.
Hi, welcome to the forum. Your history is suggestive of narcolepsy or hypersomnia. In this condition there will be excessive daytime sleepiness. In this condition there will be “automatic behavior" such as driving past a highway exit or writing off a page, with no memory of the previous few minutes.
You need to undergo tests like Polysomnography, Multiple Sleep Latency Test and CSF levels of Orexin/Hypocretin which help to substantiate the diagnosis.
What you suffer from is probably narcolepsy, which is a neurological disorder. This is thought to be caused by low protein called hypocretin, which is made in the brain. The symptoms are an urge to sleep especially after meals. Sleep studies and EEG are done to rule out other causes of poor sleep and insomnia. Eating light and frequent meals during the day helps. Also assigning a nap time during the day often helps. You can take a light meal before this.
So, I have recently found out that my hypocretin deficiency (which is the cause of mynarcolepsy with severe cataplexy) also plays a critical role in the neuroendocring system. Namely, it reduces several pituitary hormones by 50% or greater due to a defect in the hypothalamus where the hypocretin neuropeptide is produced. The hormones that are reduced are: LH, ACTH and TSH. It also greatly reduces leptin levels. (journal of clinical endocrinology and metabolism).
I hate not knowing and trying to find ways to make it through the day. Also you might want to look at narcolepsy. I thought I might have Narcolepsy, since I have the hullicinations sometimes. When the doctor told me I had hypersomnia I asked if he was sure it was not narcolepsy. He told me one of the differences is naps help people with narcolepsy, but not those with hypersomnia. And napping never made sense to me, because it did nothing to relieve the tiredness.
Narcolepsy is a CNS disorder and is thought to also be caused by an autoimmune disorder.
Causes: current thinking is that a group of cells in the brain responsible for sleep-wake behavior is damaged or absent. (gosh do you think the MS lesions might also damage this area for people unlucky to have both!)
Tests: The spinal fluid of most patients with narcolepsy shows the neuroprotein lacking or deficient. The neuroprotein is "hypocretin".
Hello,
Lifestyle treatment of narcolepsy includes taking three or more scheduled naps throughout the day. Patients should also avoid heavy meals and alcohol, which can interfere with sleep. Drugs which have been used for narcolepsy are Modafinil (Provigil) or Armodafinil. You should try the lifestyle measures first before going in for medicines.
You may get lot more information regarding the cause, symptoms, necessary investigations and treatment of narcolepsy as you go through this link: http://en.wikipedia.org/wiki/Narcolepsy
Are you suffering from narcolepsy? Take care and share your thoughts.
So, I have recently found out that my hypocretin deficiency (which is the cause of mynarcolepsy with severe cataplexy) also plays a critical role in the neuroendocring system. Namely, it reduces several pituitary hormones by 50% or greater due to a defect in the hypothalamus where the hypocretin neuropeptide is produced. The hormones that are reduced are: LH, ACTH and TSH. It also greatly reduces leptin levels. (journal of clinical endocrinology and metabolism).
Diagnosed with Narcolepsy. Have history of pituitary microadnoma high prolactin. PCOD historectamy 2002 On dostinex. Can something in my brain cause this. I am now on ritalin 20SR twice a day. Awake but body still tired. Also that thyroid medication had it irradiated a year ago Due to high levels.
Is there any other answer for sleeping so much. Or am I just in denial.
I was diagnosed with narcolepsy at age 25, took adderall ufor 5 yrs. then stopped for 1 yr to become pregnant. I took pro vigil for appr. 6,so. W/0 any help, des. Increased med and it sent me into violent emotions. I have had a recent MRI because of headaches. I need hello. I don't want the diagnosis of narcolepsy but I can't live like this.
Recommended
