My problems began very recently, and manifest themselves through constant rectal urgency. Colonoscopy revealed rectal ulcer, and biopsy confirmed SRUS. GI believes the problem is likely caused by a partial prolapse and is trying to treat it medically with a combination of Metamucil and Canasa.
My symptoms have improved some while on these meds, but this problem with a constant sour taste in my mouth has appeared.
Over the last 6 months to a year I have experienced intermittent diarrhea and rectal bleeding as well as occasional abdominal cramping. Rectal bleeding can occur without BM and will turn water red. Hgb dropped from 14.3 to 12.9 over 10 days. Most recent episode experienced diarrhea, bleeding, fever, severe cramping, weight loss, and anorexia. Initial stool cultures were negative. Colonoscopy revealed mild proctitis and grade I hemorrhoids.
During moderate/sever flare-ups I took prednisone orally, in foam suppository as well as mesalamine orally and through suppository. In moderate flare-ups mesalamine orally w/ mesalamine suppositories.
My question is - beyond the general risk that HSV presents - how additionally risky is this for me? It is a possibility that at some point I will have a flare-up that will require immonusuppressive therapy. If I was to contract HSV could my UC symptoms become more severe?
Hi Nicky.
I'm sorry about your recent U.C. diagnosis.
According to the mfg:
"The dosage of Mesalamine 500 mg suppositories (Generic Canasa) is one rectal suppository once daily at bedtime.
The suppository should remain inserted for one to three hours or longer, if possible. The normal course of therapy is from three to six weeks depending on symptoms and sigmoidoscopic findings".
So the 30 day supply falls within the recommended duration.
30 for no reason with strong chest pain, felt hot but no fever (walgreens thermometer marked highest 99 deg F for sublingual and 99.9 deg F for rectal. Each symptom lasted for about a week. I had lost appetite and lost around 10 lbs. The whole month of January was horrible. I felt depressed stressing this whole time about HIV.
I consult a gastro and go in for a colonoscopy first week of Feb. He found nodules on the sigmoid-rectal area.
Her gastroenterologist started her on Mesalamine (4 capsules daily) and later added prednisone 100 mg enemas to try and get the flare-up under control. Things are getting better and she has some of her strength back. There is one puzzling thing that the doctors are not able to pinpoint. This is an intermittent fever that starts in the afternoon and lasts to the night. In the morning the temperature is back to a low 97 degrees fahrenheit and stays stable until afternoon below 98 degrees.
My recent result of biopsy after the colonoscopy indicates epithelial dysplasia. My doctor just advice me to continue taking the mesalamine (Asacol) Do i need an another urgent medication/treatment for dysplasia? What should be my next move?
I have read about a study in which Boswellia was used in conjunction with Mesalamine. My gastroenterologist knows notheing about herbs, but is open to information that I can give her. What is available? Are there any interactions with boswellia and mesalamine that I should be cautious about? Are there any precastions about its use?
Hi there,
I was diagnosed with sigmoidal colitis in 2005, but I reckon that it went unchecked for about 4 years prior to that. I was initially treated with mesalamine (Asacol) but it had no effect. My GI guy then hit me with prednisone and that knocked it down. I have been on Asacol in a prophylactic capacity since (800mg tid). Does it keep me in remission. Maybe, but maybe it is the tremendous quantities of fentanyl, diacetylmorphine and morphine I abused as well for all I know :P.
There have been a few cases of liver failure possibly related to the use of mesalamine (the active ingredient in Asacol HD), but I haven't read anything about fatty liver as a side effect.
A fatty liver, it takes between 6 months and 2 years to fully reverse. Dr Sandra Cabot's article "Fatty Liver - What Is Fatty Liver And How To Reverse It?
She again had colonoscopy and histological examination inferred that it was ulcer. She is being treated with Mesalamine and now she is well. Please check with your doctor.
The periods of remission can last from weeks to years."
***
Springer - Mimics of Ulcerative Colitis...
"Infectious colitides such as Clostridia difficile, hemorrhagic E. coli, Campylobacter, Aeromonas, and Salmonellosis can often present as severe ulcerative colitis. Other infectious pathogens, which also need to be included in the differential diagnoses, include Amebiasis, Shigellosis, Cytomegalovirus, and Rotavirus.
I have Crohn's also. I'm pregnant with my second child and have not had a problem either time. However, my doctors did tell me that if you're Crohn's is under control when you get pregnant, it's likely that your condition will stay the same or get better during pregnancy. If you're having a flare up or the disease is not controlled well when you get pregnant it will likely get worse.
In terms of medication I would trust your doctors here.
If it is not effective, then other medications like steroids, mesalamine and bismuth subsalicylate may be tried.
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The information provided is for patients’ education only and is not a medical advice. Always consult your personal physician for complete evaluation of your health problem.
- Ratnakar Kini M.D.
But I can deal) but I heard they also sometimes do a rectal exam and that is such a no go to me its not even funny. Totally freaks me out...just wondering how many peoe have actually had this? Do they do it every time? Is it a mandatory first visit thing or do they only do it if they suspect something's wrong? This is a legitimate phobia for me..
Hi, I was wondering- what would be the symptoms of rectal gonorrhea? I was rimmed and fingered by a guy 2 months ago. I had a rectal swab taken 5 days later which was negative, is this reliable? Are there any other infections I could have gotten from this exposure? Also, would a rectal gonorrhea or chlamydia infection show up on a urine test? Thanks guys!
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