Letrozole and breast cancer
Common Questions and Answers about Letrozole and breast cancer
femara
Interesting question here. I participated in the Tamoxifen and Raloxophene five-year breast cancer study (2000 - 2005). This required completing questionnaires about possible side-effects experienced, and one of the questions was "do you have dry mouth." First time I'd ever heard of it, but yes, since I was on the study I had dry mouth. I've been off the study now three years and continue to have dry mouth, sometimes worse than previously.
Hello,
Letrozole i s used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. It is not used for fertility treatment rountinely.
Consult a gynecologist to discuss about the treatment options.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided.
Letrozole is usually used for treatment in breast cancer ..its possible they are also using it for treatment of precocious puberty...Lupron is usually the med used and I would tell you there are many problems associated with the use of it .So I have to say you need to ask for other opinions for your child maybe another doctor .
com/sites/articles/archive/2013/06/30/dagostino-cancer-research.aspx) is quite good at dealing with Breast Cancer in the brain. It works by trying to reduce the intake of Carbohydrates and Calories massively, aswell as protein. The reason for this is that the regular body cells are flexible enough to change accordingly in response to this, whereas the cancer is not. Therefore, it will starve to death.
Any other treatments would be appreciated more than anything in the world.
Hi, my mom (79 years old) was diagnosed with breast cancer last week, I think it's stage I (less than 2cm in size, and lymp nodes are fine, whole body ultrasound scan + lung/head CT are also fine). here is her report:
ER + 90%; PR + 40%; AR + 70%; C-erbB-2 ++ (waiting for FISH results); P53 -; Ki-67 + 20%; CK5/6 -; E-cad +; EGFR weak +
Doctor has prescribed letrozole (mainly because of her age).
I'm thinking surgery might be a better option. any advice?
Thank you!
A mass of breast cancer is actually composed of a mixed population of cancer cells. Some cells are strongly ER positive, some only mildly so, and some are even ER negative (do not contain estrogen receptors). When exposed to an aromatase inhibitor like letrozole, those cells which are strongly ER positive are very susceptible to the effects of this drug and either die off or stop multiplying.
December 14, 2009 (San Antonio, Texas) — New results coming from 2 mature trials with exemestane (Aromasin, Pfizer) suggest that this aromatase inhibitor differs slightly from the other 2 available products, letrozole (Femara, Novartis) and anastrozole (Arimidex, AstraZeneca).
Although all 3 are aromatase inhibitors, exemestane is a steroidal product that binds irreversibly to the estrogen receptor; the other 2 products are both nonsteroidal and are reversible inhibitors.
my mum has been diagnosed with breast cancer - she is on letrozole and needs to have the breast removed (a tummy tuck will provide fat for reconstruction). The lump is 2.5 cm big but there is puckering on the skin. The doctor said that this is advanced due to the puckering but they will not know how bad it is until after surgery. I am petrified, does advanced mean this it is more likely to have spread to organs etc. I just keep focusing on how bad 'advanced sounds. I thought that 2.
So then they prescribed four days worth of some other type of drug which is also primarily used for breast cancer treatment and pretty much works the same way as the femara called tamoxifcan or something similar. I can't remember I don't have the bottle in front of me. It's similar anyway. I just finished taking my second dose of it so I have Friday night and Saturday night to go.
The most common type of breast cancer begins in the breast ducts (ductal carcinoma). Some breast cancers contain both lobular and ductal cancer cells.
Invasive lobular carcinoma typically doesn't form a lump, as most women expect with breast cancer. Instead, invasive lobular carcinoma more often causes a thickening of the tissue or fullness in one part of the breast.
At its earliest stages, invasive lobular carcinoma may cause no signs and symptoms.
Of course the dose you take for fertility purposes is much lower compared to taking it for breast cancer. I did a little research on my own and found that Letrozole is actually much safer than clomid. I've been on letrozole for three months now, and I don't have any of the side effect I had with clomid. I have had good and healthy ovulation since I started taking it.
Good luck and baby dust to you!
I finally broke down after 26 mo of TTC, 8 clomid cycles, 2 IUIs and trigger shots and went to the RE for advice. After AF shows in 2 weeks or so - we will start on letrozole with CD3 blood work and U/S and then do another IUI. If that is unsuccessful - we will do IVF. Has anyone done letrozole vs clomid? side affects? BFPs?
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FEMARA (letrozole tablets) is approved for the adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer. It is also approved for the extended adjuvant treatment of early stage breast cancer in postmenopausal women who are within three months of completion of five years of tamoxifen therapy. Side effects that are comparable between Femara and tamoxifen include night sweats, weight gain, nausea and tiredness.
Many studies have shown that there is sufficient evidence to support that Arimidex or other similar drugs, reduce significantly the risk of recurrence as well as cancer in the opposite breast, especially if you had an aggressive type of breast cancer.Unfortunately,this medication which is a "necessary evil", does cause a lot of side effects,but the benefits must always be weighed against the possible risks.
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