2% of resistance only for those without lamivudine/telbivudine (sebvivo) resistance so who took these drugs cannot use entecavir safely, it is also better to check for these resistance mutations before starting entecavir therapy because these mutations can happen also naturally not only taking lam or telbivudine (sebvivo)
check here for more info on hbv and tests
http://www.medhelp.org/health_pages/Hepatitis/HepB-Introduction--Welcome-Page/show/34?
What will happen if an athlete with Rhabdomyolysis continues to play his sport? What will happen in the long run?
Since you know your CK levels, I assume you've seen a doctor about this? Do you have other symptoms, like muscle tenderness, nausea, etc?
In any case, high CK and dark urine are among the signs of rhabdomyolysis (google it), which is not a Good Thing. It's a breakdown of skeletal muscle. It can be caused by too- vigorous exercise, especially when dehydrated, among other things.
stop lamivudine immediately or switch to tenofovir, it is decades now lamivudine is not used because it can lead to cytopatic hbv mutations that cannot be control with any medication leading to cancer and cirrhosis despite hbsag negative, hbvdna undetectable and normal ast-alt, another reason not to use lamivudine is that it is even totally useless on hbv
the hbsag of the virus mutates to a form where the virus destroy cells directly even without replication
hbv cure is achieved only by sequen
Without taking any drugs, viral load was 22,000 in september 2009. 46,000 in december 2009. Doctor recommended lamivudine in January. Took lamivudine and by June 2010, viral load was undetected. have read in many forums that lam is not the best, approached my doctor with this concern and she sugessted tenofovir. Should i start tenofovir immediately, how should i start. Should i just abruptly stop lam and move on to tenofovir, should i use both and gradually stop lam after a few day/weeks.
This intense pain is a symptom of rhabdomyolysis,a rare condition that causes muscle cells to break down. This does not make your muscle tissue "mushy", it just causes cells t breakdown.
The most common signs and symptoms of rhabdomyolysis include:
* Severe muscle aching throughout the entire body
* Muscle weakness
* Dark or cola-colored urine
These symptoms usually occur in the first 90 days of treatment and happen in less than 1% of those taking Lipitor.
Hepatic decompensation was not prevented by lamivudine compared to placebo or entecavir compared to lamivudine in three underpowered trials.
Hepatocellular carcinoma was not prevented in four studies with inadequate size and duration. In one RCT, analysis that adjusted for country, sex, baseline ALT level, Child-Pugh score, and Ishak fibrosis score and excluded five individuals who developed HCC within the first year of the study found a borderline significant effect of lamivudine.
10.300 copies/ml . I got lamivudine 100 mg /day vitamine E 4oo ui /day, orange juice everyday 50 cc/day ,and others fruits,2 months later my blood test showed DNA/HBV/PCR negative (<200 copies ),checked regularly every 3 months untill now still negative level. SGPT 75- 90 ui/ml constantly,never down a normal range,since 2008 March untill now. HBsAg negative level ,HBsAb negative level ,others test are normal levels .Is i got recovery from Hepatitis B ?
I have tested positive to Hbsag for more than a year now. I was placed on lamivudine, methionine and essential forte. d doctor never ask me to do viral load test anytime I see him he do ask me to do LFT and subject me to d early medications I listed. so a friend advice me to go teaching hospital were I can see a specialist. my question here is now that I have been on medication for a year without knowing my viral load what is d implication ?
BACKGROUND: Nucleoside analogues such as lamivudine for chronic hepatitis B have an excellent safety profile while patients are on therapy but reactivation flares occur in 19-50% of patients after stopping therapy, some of whom develop liver decompensation. AIMS: To describe and report three cases who developed fatal hepatitis B reactivation after stopping nucleoside analogue therapy.
Vytorin does a remarkable job of reducing your Cholesterol, much better than Zocor (Simvastatin) alone. However, Zetia doesn't seem to add anything to the picture as far as preventing heart disease is concened. But read this about Zocor:
-"Zocor Users Not Warned of Risks:
The FDA's June 2011 safety alert is the most serious of many warnings regarding Zocor and associated risks of myopathy and rhabdomyolysis. Zocor manufacturer Merck & Co.
I am a 26 year old male having hbsag and hbeag=+ve,hbv dna =1070 iu/ml(Taqman) but my LFT results are normal(sgpt=37,sgot=33).My doctor has asked me to take lamivudine 100 mg for 6 months or until hbv dna becomes -ve.My mom is taking lamivudine for the last 7 months after her hbv dna crossed 8 lacs iu/ml.Probably I have been infected from my birth.Is it possible for both of us to completely cure Hep. B after taking lamivudine.
Rhabdomyolysis is a life-threatening condition that results from myositis, a condition which destroys muscle cells causing pain, particularly in the calves and lower back. The condition can become so severe that it leads to kidney failure. Symptoms of rhabdomyolysis include, but may not be limited to, muscle pain, weakness, tenderness, fever, dark urine, nausea, and vomiting.
1. I am HBV carrier, and I am also under treatment with taking lamivudine 100mg daily. Will this impact the result? Will lamivudine/HBV virus cause false negative?
2. Because I am taking lamivudine daily, will this cause the delay of seroconversion. I think the test was done about 18 months after events that I thought maybe risky.
3. My test is Combo TypeI/II antibody and p24 antigen QUAL CMIA. Is it reliable?
4. My HBV DNA level is sometimes undetectable, but sometime a few hundreds.
I am a 26 year old male having hbsag and hbeag=+ve,hbv dna =1070 iu/ml(Taqman) but my LFT results are normal(sgpt=37,sgot=33).My doctor has asked me to take lamivudine 100 mg for 6 months or until it becomes -ve.My mom is taking lamivudine for the last 7 months after her hbv dna crossed 8 lacs iu/ml.Probably I have been infected from my birth.Is it possible for both of us to completely cure Hep. B after taking lamivudine.
MB bands which are Cardiac Bands and MM bands which are muscle bands. Weight lifters or people with rhabdomyolysis can knock the MM bands way out of whack. Muscle breakdown will throw the MM band quite high.
I was examined by my first doctor and advice me that I am not qualified for medication but my employment requires to pass this Hepa B case so I look for another doctor that could give me something for medication.. The doctor and give me Lamivudine(Zeffix)..
My question is; Is there someone in this forum that had experience with this level of UI/ml that been cured and how long?.. My employeer is waiting for my respond but I cant give them exact or approximate date when will cured..
Epivir=Lamivudine, said to be very safe for husband and wife who wish to have children. But do you have to choose Lamivudine as first-line treatment with its high resistance profile?
But in short, seroconversion from HBeAg to HBeAb COULD be an endpoint of lamivudine treatment. But no guarantee.
After treatment HBV, I took lamivudine 100 mg/day DNA/HBV is negative since May 2008. Successive (check blood DNA HBV Every 3 months).
Now after I stopped using lamivudine 2 months
-DNA/HBV: 280,000 Copies = 2,8 x 5log10.
-SGOT : 140 ui
-SGPT : 300 ui
Should I take tenofovir 0,5 mg alone or plus lamivudine 100 mg ?
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