it seems like the first line treatment for chronic hepatitis B is entecavir if patient prefers oral treatment. However, it is not always the case in south east asia which entecavir is not
cost effective, which is quite saddening, as hep B is much more common in this part of the world, asia. Therefore, doctors here always prescribe lamivudine, telbivudine for these group of patients, which antiviral resistance is a big issue, which will render the drugs not effective in the end.