Ezetimibe was found to have a 50%inhibition conc of 25micromolar, while irbesartan, a commonly used angiotensin inhibitor to reduce blood pressure, was found to inhibit at 11.9 micromolar. Both compounds have similar MW, but irbesartan is given at up to 300mg per day, while exetimibe is dosed at 10mg. Thus the combination of 30fold higher approved dose and the double micromolar inhibition potency makes, in theory, irbesartan 60 fold more potent to inhibit Hbv entry.
m currently taking Irbesartan every morning and is now controlled well. I enjoy traveling in hot conditions, some days can be up to 39 degrees. Can my blood pressure medication stand such heat if I was to say just put it in my wallet? I'm always traveling to different places and don't always have access to a fridge or ice to take on hand. If not, are there any other heat resistance BP medication i can try?
These drugs, already on the market for treating hypertension, have been shown to stabilize and in many cases (like mine) reduce aortic root diameters, depending on the dosage you take. The studies generally indicate that the higher the dosage (at least maximum FDA-approved dosage or higher), the better the results. Sufficient dosage is key; if you don't take enough of the drug, you will get no results.
Can you please advise if I am taking high blood pressure medication (irbesartan) and Altorvastatin for high cholesteron and I am also taking Tamoxafin for breast cancer (about to come off this drug), is it adviseable to take Leptin Cocoa for health weight loss or would this affect the medications?
put me on lowest dose of Losartan and I got joint pain in my thumbs and then in a knee so I weaned myself off but my BP was very high (systolic) during visit. He puts me on Irbesartan, SAME class of drug, then goes on VACATION. It's the smallest dose and I took a corner of a pill yesterday, no pill today, BP is fine, I'm in PAIN. My thumbs hurt, my right foot and left knee, I don't feel well and then I read that all of this are side effects of this drug.
I am a male 70 years of age. I have been on 150mg Irbesartan and 5mg Amlodipine daily since October 2010. This controlled by BP within acceptable limits. Since late April, however, the systolic has risen to an average of around 150. My doctor wants me to add a beta blocker to the other medications. Since last October my heart rate was averaging below 60. Since late April it is averaging around 70.
my friend just started taking trandolapril 1mg and Irbesartan its only been a couple days but she feels awful
dizzy, heart palpatations, head ache and her blood pressure is still really high 190/110
should she just stick it out?
Hi, My doctor has diagnosed a mild calcification of the aortic valve and mild to moderate aortic regurgitation. I also have mild hypertension which is controlled with Irbesartan. I'm 50 and don't seem to have any symptoms but what can I expect and what can I do to improve my condition.
Call your pharmacist or your doctor and ask if this is a known side effect of the med you're on. Ask if stopping has any risks, and if not, it's a good idea to stop and see if that solves your problem. Sometimes you have to taper off some meds but unless your BP is so high you're about to drop dead from it, most BP problems depending on your age and how long the problem has existed can be fixed by changing diet and lifestyle.
please let me know if the dosage i am taking i.e. 1/4 of 20 fluoxetine and 5mg olanzapine combo and 3/4 lorazepam is high or low.
83, The doctor has now increase my weekend dosage to 100mcg but I still feel this is not enough. I feel 125mcag along with 100mcg every other day would be more suitable for me. Please advise as I'm concern about about my baby.
76)
I was feeling a little bit hyper on this dosage. I was nervous, not sleeping , etc. I think that I seem to do better when my TSH is a little higher. I already had 100 mg of Synthroid, so I started taking the 100's, with the knowledge of my doctor, but by day 3, I was crying, emotional, and not feeling good at all. What does this mean? Was the 100 already not enough or should I try maybe alternating the 112 and 100, or does this mean that I need to stay on the 112?
If the doctor prescribed that dosage, then I would trust him/her. Zoloft is typically prescribed from 50-200mg, so your son is taking a 'normal' dosage in my opinion. I was on Zoloft a couple of years ago and had no major problems coming off of it. Just ensure when it is time to come off the medication work with your doctor and taper down slowly.
Thyroid disease and what medication/dosage that works to alleviate symptoms is just as individual as you are.
Barb's right when she said the healing takes time. I think you are doing the right thing, going up slowly and keeping track of how you feel, but try to relax a little, even though I know that's hard to do when you don't feel well. I wish I'd found this forum years ago, it's been very helpful.
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