If you are diagnosed at any time with heart disease or
stroke, you do need to stop taking
imitrex. Also, it is important to avoid taking it with any other medication that may cause blood vessel constriction, such as the common cold medication phenylephrine, which is found in for example advil cold etc.
However, age-appropriate screening for risk factors for stroke and heart disease (for example, cholesterol levels, blood sugar) is important regardless of use of imitrex.