DOC=methadone, waited about 60 hours to induce 4mg. sub. 30min later I still felt some withdrawal
and took another 4mg of sub. In another 30 min. I was feeling normal, better than normal on methadone. No more withdrawal. Methadone is a long acting opioid, so I reached about a 25 on the COWS scale, longer than necessary. I waited until I had every symptom before induction. I probably would have been fine at 48hrs, but was only going to do it once. Good luck.