Ezetimibe and cancer
Common Questions and Answers about Ezetimibe and cancer
vytorin
no normalization of ast/alt doesn t happen if there is some immune response
2 no it is not ezetimibe it is the statins added to ezetimibe and in both cases the increase of alt is similar to placebo and due to the dicrease of cholesterol, there are many posts about statins and alt increase.alt normalize continuing statins and does not reflect liver damage
3 that combo is only for those needing to lower cholesterol.
also statins like simvastatin were reported to boost response a little but better not mix 2 statins, in a report researchers of ezetimibe effect on hbv and hcv suggested the use of ezetimibe with interferon but without simvastin
ezetimibe dose is 10-20mg daily but human trials with dose 50mg daily for a limited time did not find any sides or toxicity
also be aware that the big decline will be at 48-72 weeks with your hbv mutations and hbeag negative
the difference of fibroscan between 4 and 6 is meanless, you have nothing to worry
you may try to see if intf response can be increased by ezetimibe (zetia) or smvastatin.
The researchers showed that ezetimibe inhibited HCV infection in cell culture and in mice transplanted with human liver cells. And, unlike any currently available drugs, ezetimibe was able to inhibit infection by all six types of HCV.
While current drugs are highly toxic and often cannot be tolerated by transplant patients taking immunosuppressant drugs, ezetimibe is quite safe and has been used long-term without harm by people to control their cholesterol, Uprichard said.
one after a tooth extraction and had to use 2 antibiotics (one not responding maybe for resistance)
and the recent cold which was very very mild thanks to the use of liposomal vitamin c at 40-50g daily, but now after about 2 weeks i still have little cold/cough if i dont use high dose lipo c
so nothing to worry about just wanting to confirm this effect from ezetimibe on immune system and still want to combo ezetimibe and Irbesartan, but if one was to choose among the 2 drugs (if both confirmed
There have been some reports of increased liver enzymes and elevated bilirubin and jaundice with ezetimibe. It's often combined with a statin and some of the studies are of a combination of 2 drugs so it's a little confusing as to which drug has the major hepatic influence.
I did see this article:
Liver Transpl. 2009 May;15(5):504-8.
Safety and effectiveness of ezetimibe in liver transplant recipients with hypercholesterolemia.
Hi, I was recently diagnosed with Chronic Hep B, I'm on Baraclude now, and have been on Crestor (Rosuvastatin ) for the last 10 years.
If it's better for me to change to Simvastatin (Zocor, Vytorin), I'm all for it, but want to know if there's evidence out there. I've only found mention of one study that wrapped last year, but no results from it.
Any info will be appreciated.
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Fatty liver, which often accompanies obesity and type 2 diabetes, frequently leads to more serious conditions including cirrhosis and liver cancer. The condition affects some 10 to 24 percent of the general population, according to a 2003 study in GUT, an international journal of gastroenterology and hepatology.
I live in Canada and I see here that everyone seems to talk about cholesterol numbers in 100s, where here in Canada they seem to use a different system to show counts. Does anyone know how to convert these numbers to the numbers that the US goes by so when I read these posts I can figure out where I fit in?
here are my numbers:
Cholesterol 3.84
Triglycerides 1.04
HDL 1.37
LDL 2.0
TC/HDL-C Ratio 2.
Hi there and thanks for your question and joining the forum. Please always check in with your doctor on these matters so they can guide you. Unusual tiredness and weakness is listed as a 'less common' side effect of Simvastatin. https://www.mayoclinic.org/drugs-supplements/simvastatin-oral-route/side-effects/drg-20069006. For most people it doesn't cause significant issues, however. With all medications, weighing risks and benefits to taking the medication must be done.
There was an in vitro study on ezetimibe inhibiting HBV DNA production. The ed50 was fairly low and in a similar range as lamuvidine. So it looked very interesting. But in an in vitro study you have a constant exposure to the drug, which is impossible to achieve in vivo. And the cells used are not the same as regular hepatocytes in human liver, with many differences in gene expression and cellular physiology.
I take statin and other heart medications. I do not take meat but occassionally take chicken and fish, once in a week. I have undergone neuclear stress test for last three yesrs consequitively and no additional ischemia was reported. Because of me reducing the fat intake my family also ends up reducing their fat intake, as most of the food is cooked for all members.
I was wondering whether most of us on this forum, who suffer from blocked arteries, restrict fat intake to such low level?
If this fails, which it did with me, then your statins need a turbo boost but from a different angle which will not affect the liver. We consume around 25% of fats through food and so a good drug such as Ezetimibe works wonders with statins because it helps block fat absorption through the gut lining. This method dramatically increased my HDL and lowered my LDL and trigs to rock bottom. Actually after starting this regime, my disease didn't increase for a year and has remained static.
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