Just wondering, I had a liver transplant three years ago. They said the donor had a HBV antibody but they did not detect HBV. I decided to go ahead and go through with the the transplant. The doctors said 1 to 2% chance of HBV appearing. I had been vaccinated (the three shots) about 15 years earlier and so I have HBV antibodies.
After the transplant my doctors said I should go ahead and take Epivir just in case they'd missed something.
I was wondering given the following conditions - 1) HBV is UND (<357/IU) 2) On Epivir for the last several years because after some surgery the doctors thought it was possible I had been exposed to HBV or got some tainted blood 3) previously had the HBV vaccine 15 years ago. 4) No signs of HBV.
I treated with hep b 14 years ago for 1.5 years with epivir and got hbv e antibodies and afterwards, I stop epivir and every 6 months I check my liver function and alt and ast are persistently normal. I started to check hbv dna 6 months ago as new guidelines come out. Hbv dna at six month was 5000 iu/ml and last week I checked it was 8000 iu/ml. Again both times my alt and ast are normal. As a matter of fact they are in low side of normal.
I was diagnosed Hep B 13 years ago, and have taken Epivir since 2002. I do blood test and ultra-sound every 6 months and Hep B is controlled pretty well. As you know, Epivir cause virus mutant resistance, and chance is higher for me since I have been on it for 5 years. My doctor gave me 2 choices,
1) "don't fix it until it breaks" - continue with Epivir, move to combo treatment when mutant and resistance evidence shows up.
2) "precautious way" - take baraclude.
Hi everyone,
I went to see my Dr today and he recommanded to change my medicine to Viread (I am on Epivir more than 2 years). I am wondering if it's necessary to change it now since Epivir works well with me (my DNA is 200 copies). But he was worried about resistance and mutation. Do I have to listen to him? I got Viread today but I am not sure I would start taking it from today.
-Natalie
p.s.: Do you guys drink coffee? I started drinking coffee about 4 months ago...
It is 72 hours post-exposure for me right now and I took the triple therapy that I have-- Epivir, Viread, and AZT. I took a dose of Epivir and Viread at 42 hours and then decided I was being paranoid he didn't use a condom [since I only have his word] but read your post and got nervous, so I took a dose of Epivir and Viread late by 6 hours. I started the AZT for the first time at about 72 hours.
This time i decided to check hbv dna. Here was the results today. Alt 6 u/l (6-29 u/l) and ast 14 u/l ( 10-35 u/l) and hbv dna 5500 iu/ml. Throughout my research, i do not believe i need treatment. But they say dna > 2000 iu/ml needs closely monitor, how often? I will talk to my gi doctor soon. Just need some preparation to ask appropriate questions? Any comments will be appreciated. Thanks.
Antivirals such as Entecavir (Baraclude), Telbivudine (Tyzeka), Tenofovir, Adefovir (Hepsera), lamivudine (Epivir-HBV) have less upfront side effects but their long term consequences hurt patients even more: possible lifetime dependency, resistence issue, cost burden, toxicity, possible link to neuropathy, nephropathy and cancer, etc. With all these consequences the cure rate is a miserable below 1%! That is why I choose to manage my chronic HBV with foods, herbs and adjusted life style.
Epivir=Lamivudine, said to be very safe for husband and wife who wish to have children. But do you have to choose Lamivudine as first-line treatment with its high resistance profile?
I learned that I had chronic Hep B about 14 years ago. My last DNA test (about 4 months ago) said that the viris was undetectable. I'm still on Epivir.
I have three questions:
1. Being undetectable, should I reveal that I have HEP B to a potential sex partner?
2. If so, at what level of activity should I reveal that I have HEP B-- for kissing, or oral sex, or intercourse?
3. What are the chances of my really passing the viris to someone if I am undetectable?
Thanks for your help.
Temporary headaches, high blood pressure, or a general sense of feeling ill
Nausea
Vomiting
Fatigue
Headaches
Insomnia
Rare cases of hair loss
Tenofovir DF (Viread)
An antiviral drug for people with HIV infection. When taken with other antiviral drugs, it can reduce one's viral load to extremely low levels, and increase one's T-cell counts. Tenofovir may also help control Hepatitis B.
transaminases SGPT 39 ui/l SGOT 34 ui/l HBsAg positive ,DNA/HBV/PCR: 10.300 copies/ml . I got lamivudine 100 mg /day vitamine E 4oo ui /day, orange juice everyday 50 cc/day ,and others fruits,2 months later my blood test showed DNA/HBV/PCR negative (<200 copies ),checked regularly every 3 months untill now still negative level. SGPT 75- 90 ui/ml constantly,never down a normal range,since 2008 March untill now. HBsAg negative level ,HBsAb negative level ,others test are normal levels .
Recently I discussed Hep B and its various lab readings with a Western medicine trained hepatologist according to whom unlike the assumption of many patients with HBV, particularly new patients, that high HBV DNA is horrible and is what is killing the liver cells, what hurts and damages liver cells in patients with HBV is the human immune system that tries to fight the virus in liver cells.
In June 2008 I was tested positive to hepatitis B and was on EPIVIR Lamivudine 150mg for six months and I quit taking meds and took my mind of meds but to stay healthy by eating and drinking healthy.
Fast forward to June 2014, I went ahead for a medical checkup and below is the result:
HEPATITIS B: POSITIVE
HCV: NON-REACTIVE
HEPATITIS B SURFACE ANTIBODY (Anti-HBs), SERUM (CMIA): 0.00
S.G.O.T.(AST) is 39
S.G.P.T.(ALT) is 21
Alk Phosphate is 162.3
Total Bilirubin is 0.8
Direct Bilirubin is 0.
Hi, if the viral load is greater than 20,000 IU/mL and HBeAg is negative then Interferon-alfa (Roferon A, Intron A), pegylated interferon-alfa (Pegasys, Peg-Intron), lamivudine (Epivir-HBV), adefovir (Hepsera), entecavir (Baraclude), tenofovir (Viread) or telbivudine (Tyzeka) may be used as initial therapy. There are standard protocols for therapy of hepatitis B infections, so you can clarify your doubts with your treating doctor. Regards.
There are several approved drugs in the US for “chronic” hepatitis B, including Intron A (interferon alpha-2b), Pegasys (peg-interferon alpha-2b), Epivir-HBV (lamivudine), Hepsera (adefovir), Baraclude (entecavir), Tyzeka (telbivudine) and Viread (tenofivir). These drugs slow down the virus and reduce potential liver damage. In rare cases, they may even get rid of the virus completely.
1 Does this mean I do not respond to Tyzeka?
2. Should I change to Ziread since it is approved.
3. I have experienced elbow pain, left arm, with Tzyeka.
4. Does changing drugs instead of stopping altogether cause flare up?
Previouusely I took EPIVIR for 7 years and Hepsera for one year.
Thank you.
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