enbrel injection site reaction

Hi - has anyone who has ever been on Enbrel noticed a rust-colored staining on the hands? I'm not sure if it is directly related to enbrel, but I thought I would ask. My daughter was diagnosed with Rheumatoid Arthritis several months ago, and has tried Remicade unsuccessfully. Now, she has had 2 injections of Enbrel, and just today has noticed the staining on her hands. I don't know what to think, so I'd appreciate hearing from any of you.

I find that the injection sites start itching about a week after the injection. The injection sites also have a lot of itchy, red bumps around them. I take a Benadryl at night and apply hydrocortisone cream. I use hydrocortisone cream during the day too. It works for the injection sites. Aquaphor might work for your tummy sites. I was using just my thighs up until injections 11 and 12.

I noticed that my injection site looks okay for a few days after the injection, maybe very slight redness or maybe none. About 6 days after an injection the site, including the surrounding area about 2 inches in diameter, gets pretty pink-red and a little raised. It also itches like crazy. It feels warm to the touch (warmer than the rest of me). The site stays that way for at least a week or more and then gradually fades and quits itching (over 3-4 weeks time).

I was wondering if anyone else has lingering red/bruise marks at the injection site. I have taken 6 shots so far and still have a red bruise mark at injection site after six weeks. I don't know if I'm doing something wrong or if this is typical. Could someone please help me out here. Kinda nervious about giving the shot tonight.

http://www.medhelp.org/user_photos/show/326489?personal_page_id=1282072 If all else fails you could always contact Pegasys at 1-877-Pegasys (1-877-734-2797) or check out the web site Pegasys.com. ________________ Either way you could call your doctor on Monday morning but based on what you describe and what it says in the book it sounds like a common occurrence that may very well resolve on its own. _____________ Here is a link that explains how to administer a subcutaneous injection.

Getting ready for shot # 2 tomorrow after a pretty rocky first week but have noticed that the site reaction is getting bigger every day. About a 3 1/2 inch round swollen, warm, red welt. Guess this is normal? When do they dissipate? I'm going to look pretty sexy by week 6 (not many fat spots on this scrony body) Is it Ok to inject over welts? Doesn't sound like to much fun. Isn't there a way they can just put us out for 6 months or a year...

The spot on my right leg also got bigger with my arm injection, and neither lumps seem to want to go away now! I wanted to see if anyone else has had this reaction- the injection site healing, then cropping back up a few days later. Any info would be appreciated, thank you!

I think almost everyone gets these injection sites reaactions initially on copaxone. As Alex says, it is a trade-off compared to the alternative of doing no treatment at all. For most of us, the reaction calms down as the body adjusts to this substance. It took a couple months for me before the stinging stopped. this summer I started in with small lumps from the shots - half-dollar size and smaller- and talked to SS about it. They said to talk to my neuro about alternative shot sites.

You say "how can you mess this up" but I did at first, I hadn't listened properly when the injection procedure was demonstrated to me and I wasn't massaging the site after the injection, according to the nurse this could have meant that the drug was just "sitting under my skin". I must admit that massaging hasn't made much difference. My MS nurse seems more concerned about the reactions than I am.

I took my second shot today and I noticed I still have a slightly darkened spot about 2 inches around last weeks injection site. I didn't inject into the same leg this week, and I didn't have any swelling, itching, or anything else last week. After a couple days I noticed a darkening/reddening of the skin around the site. It's just a slight difference. So little that if I try to take a picture the flash washes it out. I will try again though.

I was using copaxone I did have a itch at the injection site and a lump that lasted for days sometimes weeks. Blistering I never experienced.

I have been told to get off Enbrel for needed gallbladder surgery. My problem is that when I get off Enbrel, every joint in my body swells, turns red, hurts unbearably and locks up. I become completely bedridden and cannot get dressed or go to the bathroom without help. My blood tests show that, even with the Enbrel, my c reactives and other immune response numbers are very high. They tell me that they will give me prednisone to help with the reaction.

The last 3 of my injections have left dark circular bruises at the injection site. Previously, I did have some redness, but not bruising like this. (I'm on my 19th week) At first I thought that maybe I somehow caused it during the injection. But then the next week, I had the same kind of bruise. Now, after the last shot, this is the 3rd time I've had a bruise, and I used different spots for these 3, where I didn't have this kind of problem before.

Just started taking Enbrel self injection, haven't had RA meds since August. Feeling lighted a bit and very anxious. Is this normal and will it fade as time goes on?

PS - if the sting (or injection site rash) of Enbrel is what's causing your Mom to want to switch, definitely have her ask to be switched to the self-mixed form. There are a few steps to mixing it, but like I said before, once she gets the hang of it, she'll be done in under 5 minutes.

The things you are describing with the use of Copaxone are very common in the beginning of it's use. If there is any stinging, I would NOT use the alcohol wipes. I would clean the area with plain soap and water and dry. I am now in month 14 of Copaxone use. I still get welts and bumps. Sometimes the lumps are the size of a quarter. Some of them bruise. But I can live with that, because I know that I am taking a drug that is helping me.

Enbrel was introduced in 1998 and by the time my insurance agreed to pay for it it was Spring 1999 when I took my first injection. I started Enbrel along with an injectible dose of.09 Mtx weekly. For me Enbrel was a light-switch medication and within 2 weeks I was a normal functioning adult again with no pain at all. My only real complaint is that my hair has become substantially thinner and I am considering stopping the Mtx to see if there is an improvement.

I would like to avoid injecting in my thighs if possible due to the irritation at the injection site and the fact that my legs ache so massaging them would be difficult coupled with the irritation. I just took my 4th shot so no irritation there yet, but the first 2 places have a brown colored appearance and the 3rd site is still red, itches, and feels like a bad sunburn. All these splotches are not quite as big as a tennis ball.

Dry or scaly skin is treated by any good moisturizer, but the bumpy and rough condition you describe sounds more like an allergic skin reaction than dry skin. Again, I want to tell you that injection site skin should normally look no different from the skin on other areas of the body. Below is a web site address for an article on insulin allergies, which are rare.

I suffered the chills too after 4 shots and one month later still an injection site reaction. Apparently I am allergic to first plegridy and now copaxone. Switching to Tecfidera Sat. Wish me luck, and 3 ttmes a charm I hope.

Hello. I am not on Humira (yet) but have talked to many people who are. From what I understand, what you are experiencing is normal and that it gets better after several injections. I have also heard that you may feel better if you inject it right before bed so you can sleep through most of the side effects. Please let us know how you do and if you develop any other side effects.

Enbrel injection site reaction

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