Enbrel and hepatitis c
Common Questions and Answers about Enbrel and hepatitis c
enbrel
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In conclusion, we have observed that in patients with chronic hepatitis C treated with PEG-IFN and ribavirin, the durability of SVR exceeds 99% for up to 7 years of follow-up. Although 'late' virological relapse may occur in less than 1% of the patients, this phenomenon is mainly confined within 1 year after assessment of the SVR.
In March of 2007 I recieved the D-tap vaccine and 3 weeks later developed similar but more severe joint pain in hands and feet assoc with fatique, malaise and muscle fatique. All blood work has remained normal except for one elevated c-reactive, and a consistent slight elevation of ALT in the 70's. I also have a fatty liver, and have been on prenisone for past 3 yrs. Have also been on colchicin, metheltrexate, humira, and now enbrel.
About 9 months after I was in a car accident, resulting in cervical stenosis and a long course of PT I had severe flares for which I was prescribed prednisone for several months (May, 2007). My rheumatologist was concered about my liver functioning and diagnosed hepatitis c after a blood test. I began treatment for hcv (January, 2008), my flares subsided, however during the latter part of the 6 months of hcv treatment, the flares increased and I was in considerable pain.
I'm in the same vote. On enbrel and have developed hpv. Very tiny bumps if even noticeable at all, but its been spreading. Aldara only made my psoriasis and psa flare up. I guess the next thing is to stop enbrel till my hpv clears up? I am 29, male, non smoker. Enbrel is the only med I take.
Isn't enbrel an immunosuppressive medication? It would make sense that it would stop your own immune system from holding down the virus.
In fact, the American College of Rheumatology has recommended that the tumor necrosis factor inhibiting drugs (Enbrel, Remicade and Humira) can be used in patients with chronic hepatitis C without causing worsening of liver function.
It is important that patients and rheumatologists be aware that hepatitis C is a relatively common chronic viral infection, affecting the diagnosis and treatment of rheumatoid arthritis.
My blood tests show that, even with the Enbrel, my c reactives and other immune response numbers are very high. They tell me that they will give me prednisone to help with the reaction. If the only reason for getting off the Enbrel is to protect me from infection, doesn't the prednisone do the same thing? I can't take prednisone without major side effects, including bleeding alot over everything...wouldn't that be bad during surgery?
I've been on Enbrel for almost 9 years. I've recently been developing tremors in my hands, cheeks (when I smile), and tongue. Talked to my rheumy. He doesn't think it's the Enbrel, but I am growing more concerned. They're not bad, but they do seem to be progressing.
23 January 2008
Pegylated interferon alfa and ribavirin for 14 versus 24 weeks in patients with hepatitis C virus genotype 2 or 3 and rapid virological response
Published Online: 1 Nov 2007
Copyright © 2007 American Association for the Study of Liver Diseases
Abstract - Nov 2007
A recent nonrandomized pilot trial showed that hepatitis C virus (HCV) patients with genotype 2/3 and rapid virological response (RVR) had a 90% sustained virological response (SVR) rate after 14 weeks of treatm
I have also been through the ringer with test for a yr and 4 months now, I finally found a Doctor that tells me ankylosing spondylitas, I just started Enbrel Friday and hope it works.
Thanks smittygirl. I was on the fence with this decision but leaning in the same direction as your perspective. Sunday, today, is my injection day. I've had the p.i. for a week, and it seems to be clearing up despite the Enbrel. So like you, I agree; I'd rather itch a little, then have the chest-wall pain (my main symtom). BTW... good luck with AS. Prior to joining this forum, I read some of the past posts, and yours came forward as a real success story.
I have had two shots of Humira, I constantly have sinus issues, pain pressure, teeth hurt and hedaches. I got them on enbrel and after 9 years it quit working, so tired remicade but after 4 infusions I had such a bad insus probelm I quit it also raised my blood pressrue a lot. I don't seem to be able to handle hard core antibidoics so I can take zpack, and it helps, but I always seem to be back on it alteast every two months.
I was in between jobs and had no insurance and had to stop the Enbrel for 3 weeks, within 2 weeks the pain and stiffness was back worse than ever. The price of Enbrel is $1500.00 monthly so it doesn't surprise me that the insurance company won't give you the 2 a week you need. Talk to your doc about the other 2 drugs and see if they will better help control your pain and stiffness. Keep me posted!
I'M A MALE 59 YEARS OLD BUT WITH A VERY ACTIVE LIFE STYLE. I;VE HAD RA FOR 25 YEARS, STARTING TAKING METHOTREXATE ABOUT 5 YEARS AGO WITH PREDIZONE FROM TIME TO TIME. AROUND THREE YEARS AGO I WAS HAVING FLARE UPS AND MY DOCTOR ALSO ME ON ENBREL, WORKED VERY GOOD FOR THE RA BUT MY NOW MY THROAT IS ALWAYS SORE AND CONGESTED WITH PHELM. THIS YEAR I'VE SEEM NUMEROUS DOCTORS ENT, GENERAL ALERGIST AND EVEN HAD SINUS SURGERY FOR 30 GRAND, NOTHING FIXED THE THROAT PROBLEMS.
Here's a list of common and uncommon side effects of Enbrel: https://www.rxlist.com/enbrel-side-effects-drug-center.htm
If you get a fungal infection, you should call your doctor immediately. Since it is a known risk, your doctor will know how to treat you, and may recommend discontinuing the medication for at least some time.
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