About 6 months ago, I was finally diagnosed and started taking cyclosporine 100 mg 2x day. After a week, I could eat like a normal person—just about anything I wanted. It was great, it even allowed me to travel to Europe. The cyclosporine I was taking was a powder in a capsule, apparently this has been taken off the market and instead I took the same medication, but it was in the form of a capsule with alcohol. Unfortunately, after a short time, I was right back to before treatment.
Yes I took Cyclosporine for my aquagenic urticaria, it helped so much but not enough to have a normal life :S but maybe for you its going to be different...
very good they are continuing research, rna interference was discovered years ago by a US company but after this discovery it was bankrapt because other durg makers sueing them, don t remember why i only remember they stopped everythign and even website of this company dissapered
so rnai research continued in israel and other countries outisde US, i am very happy to know that research is being conitued in china/australia where infuence of US drug makers is close to zero, especially china
rnai
I am still on 100 mg 2x daily cyclosporine. My cyclosporine through levels have been lower, the last time they were at 79. I Have been on 300 mg ursodiol 3x daily for biliary stricture since tx. I lowered the dose to 300mg once daily but just recently raised it back to 300x 3 daily because right side discomfort an increase in bilirubin. My headaches and fluid in ears have gotten better, still have the vision issues but heart palpitations have also lessened.
s for 3 days, than a single herbal formula should slowly be introduced at a fraction of the therapeutic dose. Often the patients allergic immune system will adjust to the herbs, if they are very slowly increased over time. Once the first herbal formula is tolerated the second herb can be introduced.
Discharge from the penis and inflamed gums are not usually signs of allergy.
Inconsistent use of grapefruit juice or variability in its effect on drug metabolism could result in variable and difficult to control plasma concentrations of other medications, where maintaining a certain plasma concentration may be especially important, such as for cyclosporine or for HIV protease inhibitors like saquinavir.
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
Close to five years post liver transplant. No rejections, cyclosporine mono -therapy .Also take 300 mg ursodiol 3x daily for bile duct stricture. Vascular hyper-tensions are becoming a real concern. ie heart, palpitations . fluid in ears , vision problems that aren't related to my actual eyes, the opthamologist confirmed, Migraines that have actually gotten better lately. kidney function is still adequate. My liver is doing very good especially with hep-c..
and the vet will probably prescribe cyclosporine drops to help the eye produce more tears. Before you use the cyclosporine drops, be aware that they will sting your dogs eyes, and long term use may contribute to kidney disease...talk this over with your vet.
Since your dog is 12 years old, please have annual bloodwork done on him to assess liver and kidney functions...bloodwork should be done on all senior dogs.
Best Wishes for you and your dog.....
Lithium is one of those meds that you just have to play with. It's a trial and error type of med. Honestly, even a level of 0.9 is not therapeutic for bi-polar disorder. It should be at least 1.0 if not up to 1.5. And 0.6 is definitely not therapeutic. I was on 1500mg of Lithium once daily, extended release, and I still wasn't at a therapeutic range. Everyone is different. My metabolism just happens to metabolize lithium at a higher rate than it does for others. That might be your issue.
In an additional 33 patients, glomerular and tubular NEP protein levels from renal graft biopsies were significantly higher among the 13 patients receiving cyclosporine + EC-MPS than among the 12 patients receiving cyclosporine + azathioprine or 8 patients receiving cyclosporine alone. Glomerular NEP expression inversely correlated with glomerulosclerosis and proteinuria, and tubular NEP expression inversely correlated with interstitial fibrosis.
I am currently under St Thomas hospital for this, they are stating I should take Cyclosporine for 6 months, I was wondering if someone on here has taken this treatment and it has worked for them??, I am not convinced on this medication as I have read so many bad things about it.
My consultant has stated that 70% of people whilst on cyclosporine will be clear, one third will have total remission,one third will be same as before, one third will be worse once the treatment has stopped.
My seizures were under control for a couple of years even thought my blood results said I was not within the therapeutic range. I moved out of state and my new doctor wanted to increase my dose's so I would fall with the range. I did not care at the time and
let her raise my dose.
Talking with my new neurologist who is the Newsome chair of epileptology and director of the Epilepsy Program told me that in short the therapeutic range is different for everyone.
We immediately put her on an antibiotic ointment and cyclosporine. It has been almost 10 days and while there is less discharge, she is still having some trouble opening her eye, she just keeps it closed (unless she gets excited). At some times you look at her and she looks completely fine, others times she can barely open her eye. Is this normal for KCS? Should we have seen some major improvement by now?
I was switched to cyclosporine and Myfortic. When the Incivek was started my cyclosporine was dropped to 25 mg once per day due to their interaction. Due to my previous non-response and to the multiple variations of the HCV I carry my odds were considered to be about 30%, maybe 40% at best. At the end of week 4 the HCV RNA was not detectable. The only additional side effect is that the anemia came quicker this time. I will start Procrit injections probably sometime this week.
Serum HCV RNA became undetectable at week 3 of treatment and remained undetectable during 24 weeks of triple therapy as well as during post-treatment follow-up. Daclatasvir was well-tolerated and the trough drug levels were within the targeted range throughout treatment. The cyclosporine trough levels were also stable during and after therapy.
After joining the Forum and learning about the importance of FT3, I got mine tested and found that even though my FT4 was very high in the range, my FT3 was very low in the range.
After a med change to a combo T4/T3 med, my dosage has been tweaked until now FT4 is .90 (range is .60 - 1.50) and my FT3 is 3.8 (range is 2.3 - 4.2). I did not take meds until after the blood draw. Testing also showed a low level of Vitamin D, which is quite common with hypothyroidism, so I supplement that.
t swelling and foamy urine. Now that I have a diagnosis, I am on pill forms of Prednisone every other day and Cyclosporine 2x every day. I have been on the meds for over 1 1/2 weeks and noticed that the foamy urine amount has doubled, my face swells unbelievably, and walking is difficult, as the bottom of my feet and ankles cause me severe pain. I checked with my Nephrologist and she states that it will take a little while for my body to adjust to the medicine.
Your TSH really hardly moved. TSH can change by as much as 70% just depending on the time of day the blood was drawn. It's still above range, and AACE recommended many years ago that TSH range be changed to the much more reasonable 0.3-3.0.
FT3 and FT4 are much more important than TSH, especially once on meds. The target for FT4 is about 50% of range. Yours is at 24%. Target for FT3 is 50+% of range, and yours is 16%. So, you are still hypo.
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