Celebrex bleeding risk
Common Questions and Answers about Celebrex bleeding risk
celebrex
People with liver disease who have had internal bleeding, - from an ulcer or esophageal varices, for example, may be at risk for recurrent bleeding induced by NSAIDs, and should totally avoid this class of medications. People who are also taking corticosteroids (such as prednisone), or anticoagulants (such as coumadin) may have and increased risk of complications from NSAIDs.
These are the known side effects of celebrex, which may be more pronounced in some individuals. Though celebrex carries the risk of gastritis and GI ulceration, like other NSAIDS; the incidence is slightly lower as compared to others. Symptom of GI reflux can be aggravated by it. Rhythm abnormalities (early de-polarisation/ re-polarisation) may not be related to celebrex use.
possibly increasing the risk of a bleeding complication (e.g., gastrointestinal bleeding, ecchymoses, epistaxis, hematomas, petechiae, hemorrhage)
Celebrex and Metoprolol:
Celebrex may decrease the effectiveness of Metoprolol, and lead to an elevation in blood pressure (approximately 5 mm Hg) when given over a period of weeks. This effect is most significant in patients receiving concurrent antihypertensive agents and long-term Celebrex use.
She is 64 but she also has osteoporosis and arthritis in her lower back. The back doctor just prescribed Celebrex, is this the safest drug for her? Also what should people with Hep C do to better care for their liver eventhough so far she seems to have a healthy liver. For the osteoporosis she is on Fosamax. She has been on it for several years. I am just afraid that too many potent drugs can be harmful for her liver.
I have been taking Celebrex (200 mg a day) for about five years for bone on bone knee osteoarthritis. It has worked well for controlling my pain (not perfect but pretty good). I also get some lower back pain (combination of osteoarthritis and nerve stuff) that only happens when I over-do (like trying to garden, etc.). I typically need a day or two of Vicodin for that as the Celebrex does not seem to work for that.
This group of NSAIDs has the advantage of having fewer gastrointestinal side effects – less abdominal discomfort and less risk of gastrointestinal bleeding, than conventional NSAIDs. There are three different COX-2 inhibitors currently available to the public– Vioxx, Celebrex and Bextra. COX-2 inhibitors have been associated with some liver dysfunction, although not as commonly as other NSAIDs. Recently, Vioxx has been removed from the market due to heart-related problems.
The first pathway can slowly destroy the stomach lining and over time, cause ulcers or GI bleeding. Celebrex is the only medication that does not go down the COX-1 pathway very much. Others were developed (Vioxx and Bextra), but then recalled due to issues with people having heart problems. So, if you do not have GI bleeding or an ulcer, you may want to ask your doctor about other NSAIDS.
Has anyone used Celebrex for their Crohn's? I have severe joint point pain and I have been told that Celebrex is a huge help for this. I am wondering about side effects and medicine interactions.
People with liver disease who have had internal bleeding, - from an ulcer or esophageal varices, for example, may be at risk for recurrent bleeding induced by NSAIDs, and should totally avoid this class of medications. People who are also taking corticosteroids (such as prednisone), or anticoagulants (such as coumadin) may have and increased risk of complications from NSAIDs.
Hi all, recently diagnosed with Achilles tenosynovitis, and treatment of celebrex is not doing the trick. Not using it normally but cannot rest 24/7. Was not given crutches, concerned my weight (I'm about 40 lbs overweight) is hindering my recovery. Still in pain, limping and have some swelling - all docs told me it should be normal in a few days with the celebrex. I'm traveling and cannot afford to be immobile.
People with liver disease who have had internal bleeding, - from an ulcer or esophageal varices, for example, may be at risk for recurrent bleeding induced by NSAIDs, and should totally avoid this class of medications. People who are also taking corticosteroids (such as prednisone), or anticoagulants (such as coumadin) may have and increased risk of complications from NSAIDs.
This group of NSAIDs has the advantage of having fewer gastrointestinal side effects – less abdominal discomfort and less risk of gastrointestinal bleeding, than conventional NSAIDs. There are three different COX-2 inhibitors currently available to the public– Vioxx, Celebrex and Bextra. COX-2 inhibitors have been associated with some liver dysfunction, although not as commonly as other NSAIDs. Recently, Vioxx has been removed from the market due to heart-related problems.
Does anyone take celebrex?I started Prozak last week and they want me to take celebrex too. They say my liver can take it, (stage 2 fibrosis). But I am afraid of the NSAIDs in celebrex, any one else taking it? Oh, I am on Methadone too. I am having my first liver biopsy in the morning, so I will find out more about my liver. I am scared to death about it coz I have had so many problems lately.
No, it would be unheard of for Celebrex to damage your heart valve. Celebrex and similar drugs do cause high blood pressure in many individuals, though.
You might have gone forever and not known about the heart valve if you had not gotten high blood pressure from the Celebrex. Follow whatever advice the cardiologist gave you, and don't worry.
I never had high blood sugar but recently after a 10 day course of celebrex for an inflamed shoulder muscle my fasting blood sugar shot up to 137. I read that celebrex has this side effect. Is it reversible?
Trying a new drug for pain... Celebrex. I was on Diamox but could not tolerate it as it caused severe kidney PAIN. So, my PCP wants me to try Celebrex (3 days on, 3 days off). Anyone have any experience/knowledge of this med and, if so, how did you fare with it?
s normal defenses to stop the bleeding are impaired, leading to bleeding for a longer time, increasing the risk of a larger hemorrhage. Therefore, while the anti-inflammatory effect of NSAIDs could potentially help cavernous angiomas (theoretically), the reason they are avoided in patients with cavernous angiomas is because of the risk of bleeding.
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