Celebrex and cardiovascular risk
Common Questions and Answers about Celebrex and cardiovascular risk
celebrex
Compared with non-users, the association was strongest for new users, with a 40-70% increase in relative risk (lowest for non-selective NSAIDs and highest for COX 2 inhibitors). So, the evidence proves that atrial fibrillation or flutter needs to be added to the cardiovascular risks to be considered when prescribing NSAIDs.
I was recently diagnosed with rheumatoid arthritis and prescribed Plaquenil and naproxen (for swelling and pain relief.) I am on a low sodium diet for meniere's disease. Various pain relievers make me retain fluid......making me too dizzy and light headed to drive. Can you recommend a product, OTC or prescription, that contains little to no sodium? I have read the sodium in pain relievers help to quicken relief of pain......
I am writing on the connection of cancer in general (but breast cancer is specific) on cardiovascular risk associated with breast cancer. I am aware that treatment, whether it be chemo or radiation, can cause issues but I have been unable to find anything to support that the cancer itself causes problems. My prof assures me that it does. If anyone could help me out, or point me in the right direction on this topic I would be very grateful.
She is 64 but she also has osteoporosis and arthritis in her lower back. The back doctor just prescribed Celebrex, is this the safest drug for her? Also what should people with Hep C do to better care for their liver eventhough so far she seems to have a healthy liver. For the osteoporosis she is on Fosamax. She has been on it for several years. I am just afraid that too many potent drugs can be harmful for her liver.
There are published studies of vitamin D levels and the risk of cardiovascular disease. Vitamin D levels greater than 30–40 ng/mL (75–100 nmol/L) may lower atherosclerosis risk. If this disorder reaches advanced stages, a physician should be consulted.
How vitamin D works
Vitamin D may reduce atherosclerosis in several ways:
Reduces inflammation: Vitamin D shifts cytokine (protein) production away from inflammation. Internal swelling causes plaque lesions to develop.
2 times and less than 3 times the upper limit of normal) of liver associated enzymes was 6% for CELEBREX and 5% for placebo, and approximately 0.2% of patients taking CELEBREX and 0.3% of patients taking placebo had notable elevations of ALT and AST.
A patient with symptoms and/or signs suggesting liver dysfunction, or in whom an abnormal liver test has occurred, should be monitored carefully for evidence of the development of a more severe hepatic reaction while on therapy with CELEBREX.
These are the known side effects of celebrex, which may be more pronounced in some individuals. Though celebrex carries the risk of gastritis and GI ulceration, like other NSAIDS; the incidence is slightly lower as compared to others. Symptom of GI reflux can be aggravated by it. Rhythm abnormalities (early de-polarisation/ re-polarisation) may not be related to celebrex use.
I don't think it should be an issue, I took Celebrex and Morphine for an extended time with no issue. Ask your doctor about any concerns though.
My two daughters take Celebrex as a person would take Advil here or there and do fine with it .. they both cannot take ibuprofen. My son cannot take it since birth as he gets bad reflux from in ..
They make custom made ibuprofen suppositories if you really need a NSAID but cannot do it by mouth and they are wonderful .. you need a compounding pharmacy but my co pay was only $8.00!
Has anyone used Celebrex for their Crohn's? I have severe joint point pain and I have been told that Celebrex is a huge help for this. I am wondering about side effects and medicine interactions.
They believe that their results are of such importance that “a randomized placebo-controlled interventional trial is crucial to determine what effect vitamin D may have on surrogate markers of CVD [cardiovascular disease], as well as on immune function and reconstitution, and to determine what vitamin D level is optimal in HIV-positive patients.”
Earlier research has already shown that vitamin D deficiency is common in patients with HIV.
I have been on methotrexate and celebrex for at least 15 years, probably long. I am currently in a tremendous amount of pain in my fingers, elbows, shoulders, left knee and left hip. Volteran gel has not helped at all and neither has Aleve. Can I take tramadol with these two drugs? I have recently switched my insurance and am waiting to get into a new rheumatologist.
t really that affective for me but my insurance made me try practically every NSAID on the market before they would approve Celebrex. They denied Celebrex and even recommended a PPI (ulcer med) to take with the NSAID's because they didn't want to pay for Celebrex. After they denied me 4 or 5 times, they finally approved it. So now I take 400mg of Celebrex a day and it's a lot more effective than any other NSAID i've been on.
Usually, blood pressure is assessed with multible heart cycles at least for a minute, and that would then include the heart rate.
The etiolgy of a serious valve disorder would be to reduce the cardiac output (CO is stroke volume for each heartbeat times heart rate). Under other physiological conditions, there would be an increase in heart rate and increased blood pressure. "Increased HR leads to increased cardiac output, among other things, which increases blood pressure".
I don't what know the doctor here will say but several studies have shown/suggested that persons with Gilbert's disease/syndrome are at lower risk for CAD and other cardiovascular events.
Hi all, recently diagnosed with Achilles tenosynovitis, and treatment of celebrex is not doing the trick. Not using it normally but cannot rest 24/7. Was not given crutches, concerned my weight (I'm about 40 lbs overweight) is hindering my recovery. Still in pain, limping and have some swelling - all docs told me it should be normal in a few days with the celebrex. I'm traveling and cannot afford to be immobile.
If I understand, your father recently had a stroke and the underlying cause is cardiovascular disease and resulted in a stroke. That occurs when a blood clot is dislodge in the vessel and with blood flow goes to the brain and blocks a segment of the brain to blood supply. The result can minor with very little impairment or serious causing a loss of mobility and speech.
If in the 3mg/l-- 10mg/l range or higher, she is at greater risk for the stent to thrombose or the plague to rupture---putting her at risk for acute cardiovascular events? If high, get more aggressive in getting her LDL and CRP down and give her meds to help pain in knee.[ She is walking and going to cardiac rehab, so she is not immbolized.] Thanks for your help, R.N.
This is due to the fact that a high pulse pressure (the difference between systolic and diastolic) is a marker for arterial stiffness and risk for heart disease and stroke. A high diastolic signifies a lower pulse pressure and lower risk. This information caught my attention as more than occasionally I have a high pulse rate. Evidence suggests that pulse pressure may be a strong predictor of heart problems, especially in older adults.
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