alendronate mechanism of action

if the mechanism of action is to decrease osteoclasts (thereby dead bone cells are not removed) - is this helpful to have denser bones made of dead bone tissue? I am thinking it may be better to increase calcium, improve general mineral, Vit D nutrition and get another bone density test as opposed to taking biphosphonates. If my bone density doesn't improve then I will consider taking it for up to 5 years.

Until recently, the principal treatment has been resection or fracture repair, although the latter is often palliative at best. However, new insight into the molecular mechanism of fibrous dysplasia has led to the use of bisphosphonates to treat this disease. The authors examined the effects of high-dose oral alendronate (40 mg daily) for 6 months on 3 adult patients with intractable headache due to fibrous dysplasia of the skull. Each patient had disease processes not amenable to surgery.

Until recently, the principal treatment has been resection or fracture repair, although the latter is often palliative at best. However, new insight into the molecular mechanism of fibrous dysplasia has led to the use of bisphosphonates to treat this disease. The authors examined the effects of high-dose oral alendronate (40 mg daily) for 6 months on 3 adult patients with intractable headache due to fibrous dysplasia of the skull. Each patient had disease processes not amenable to surgery.

I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?

The mechanism of action of Campral® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.

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Oyakawa I am in my 3rd year of medical school and I was wondering the mechanism of action of steroid injections in the eyelid causing cataracts. It is not an osmotic agent so why does that occur? thanks so much.

Moderate daily exercise, to include walking and isometrics are helpful because mild stress on bones stimulate the growth mechanism. The goal of treatment is to prevent fractures, decrease pain, and maintain function. Men with osteopororis also require evaluation for androgen deficiency.

I took my first dose of Alendronate and then experience significant muscle pain for the next 4 days. Does anyone know if I should expect this to happen each time I take it or is it something to happen for the first few times until my body adjusts to the medicine?

Thanks for posting this DV. My favorite part was the mechanism of action for Tecfidera. "Poorly understood...

Do you mean Fosamax (alendronate)? If you do, its for treating bone problems like Osteoperosis by adding bone mass and slows bone loss. I use it for Osteopenia.

Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.

My wife is a 65 year old in good health who has taken FOSAMAX for 5 1/2 years. She wants to get her teeth straightened. The periodontist has recommended a procedure to reinforce the gums prior to the braces. This has added an additional 6K to the price and about 3 months to the total time to straighten the teeth.

HIV is transmitted by; Unprotected penetrative anal and/or vaginal sex Sharing works with other IV drug users Mother to child You never had an exposure.

Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.

http://www.medscape.com/viewarticle/578705 Ribavirin improves early responses to peginterferon through improved interferon signaling. Gastroenterology. 2010 Jul;139 The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of interferon-stimulated genes. We evaluated viral kinetics, serum cytokine expression, and viral mutagenesis during early stages of peginterferon therapy with and without ribavirin.

Seeing an orthodontist is advised.

Some medications are actually derived from plants. The mechanism of action and effect on the body determines the classification, therefore, laxatives can be synthetic or natural.

"Mechanism of Action Oxomemazine, a phenothiazine derivative, is a sedating antihistamine" The above information is about all I could find on this drug. If it is used in the US, I have no idea what label it's under. Even if I had been able to find more information, I am not qualified to tell you to either stop or start or change any medications. You need to speak with your doctor or chemist for an answer to your question.

, duloxetine) has a combination mechanism of action involving serotonin and norepinephrine making it useful in depression and also neuropathic pain. When a peripheral nerve is injured there is an increase in pain sensitive fibers leading to increase pain recognition. This causes a change in central (i.e., brain/spinal cord) recognition of pain. One major neurotransmitter involved in this is norepinephrine. Cymbalta works to modulate this change.

A heart murmur is a sound heard as the blood flows through the heart and especially the blood flow through the heart valves. If there is a defect, a stethoscope hears a specific sound for different defects. ■Angiotensin-converting enzyme (ACE) inhibitors. ACE inhibitors lower the system's blood pressure. The mechanism of action is to relax the blood vessels and that provides less resistance for the heart to pump against and decreases blood pressure.

boceprevir is in pharmacies now telaprevir should be by the end of the month they both have the same mechanism of action ( protease inhibitors ) and are comparable in efficacy mimi that 70% is for first timers only

It is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. Its exact mechanism of action is unknown but is thought to be similar to morphine. Hope it helps.Take care and pls do kep me posted if you have any additional queries.

When the mosquito bites my hiv+ friend, get s interrupted and bites me immediately after with the blood of my hiv+ friend on its mouth? I know mosquitos do not inject blood in human bodies, they just suck it out. But if blood present due to an interrupted feeding episode, small amounts of blood would have been present.

Alendronate mechanism of action

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