phenytoin and gingival hyperplasia

Taking the drug with food may reduce some symptoms, however, clinicians should keep in mind that oral administration with continuous nasogastric feedings can significantly impair phenytoin bioavailability. Gingival hyperplasia is a adverse reaction in children and young adults, especially during long-term therapy. Emphasis should be placed on good oral hygiene and gum massage. Cataracts have also been rarely reported after long-term therapy.

Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..

The antiepileptic drugs need to be checked for a dosage modulation, assessment of adverse effects due to chronic usage over years like megaloblastic anemia, gingival hypertrophu and osteomalacia with phenytoin. Take care.

Hi everyone, I'm new to this community. My neurologist just informed me that Osteoporosis and shrinkage of the Cerebellum are very serious side effects for long term users of Dilantin. Does anyone know more about this? I've been taking 500mg of Dilantin for over 30 years since I was a teenager, and now I'm terribly worried. Not one of the neurologists had mentioned anything about this over the years, and now at 46, I've learned that I may have severe osteoporosis.

black female 46 with exessive hair growth (chest, chin, upperlip been tested all came back normal not sure what test was done only know it was a hormone levels test no sonogram i have been shaving for years because cant find the source of the problem i have develop hyperpigmentation and holes and my face what can i do to get rid of it and is it wise to keep searching for a solution to my problem i have seen a (endrocrinologist, gyn) i have not seen a dermatologist

It is usually done in periodontitis where huge pockets are present, but for a RCT. Not sure, unless there is gingival hyperplasia present or something along those lines. Removing gingiva just for the sake of crown, seems like it may rise issues with biologic width. Mean_KItty was the need for the gingivectomy explained to you? By law they should tell you the procedure and why they are doing that.

one year ago in February I had a series of infections then started to gain weight despite being very physically active and on a very strict diet. I gained 60 lbs in 7 months started to get head aches, nausea, severe fatigue(yes I have had a pregnancy test every time i go to a doc, not pregnant), I have trouble with my body temperature getting hot flashes and sweat when I'm cold, I developed very severe mood swings that go from very mad to very sad.

During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.

Hi, you are right .Dilantin does cause gingival overgrowth and enlargement. These effects usually start appearing after 1-3 months of its usage. The excess gum tissue interferes with cleaning and tooth decay and periodontal disease becomes more prevelant.I will advise you to regularly schedule your appointments with the dentist for removal of plaque in the inaccessible areas of your teeth. Rinse your mouth thoroughly with chlorhexidine.Eliminate unnecessary sugars from your daily diet.

s blood in my chopsticks ,and then i used them and then i had a gingival bleeding , i still have no risk of HIV,right ? I AM REALLY SORRY TO ASK THE SAME QUESTION AGAIN. BUT I AM TOO AFRAID . plz answer me for the last time . thank you soooooo much!!!

Yes they sent the specimens for a second opinion to pathologists, and it was atypical cells and hyperplasia...I am to be scheduled for a lumpectomy next....my surgeon said he didnt think I would have to have chemo but maybe radiation, if they find cancer. Thank you for your reply. I think he is thinking they got this early so it would not be invasive...but I am guessing at that.

Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..." It however says that initiation of Folic acid and phenytoin together is beneficial. Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.

Combining fluoxetine or paroxetine with phenytoin can also lead to increased phenytoin side effects and reduce blood levels of paroxetine. You really need to discuss the potential drug interactions with your own doctor.

Many patients are wrongly identified as prostatic hyperplasia and chronic prostatitis. Although prostatic hyperplasia is very just like chronic prostatitis during the early stage, they may be two different diseases. What are the symptoms of prostatic hyperplasia and chronic prostatitis? How to distinguish between prostatic hyperplasia and chronic prostatitis?

You should tell your doctor if you experience any of these symptoms while taking phenytoin, so that your blood level of phenytoin can be measured and your dose reduced if necessary. " Also, he has had a major surgery, and will need time to recover. However, any changes need to be reported to the doctor.

What are some treatment options for gingival embrasures? They have become more prominent since I did deep cleaning last year.

Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.

Whereas if you are a chronic alcoholic, the phenytoin levels may be lower than expected and can cause seizures. I suggest you consult with your neurologist in this regard. Hope this information helps. Take care.

Sudden onset of generalized gingival swelling in young children is commonly associated with primary herpes infection. Seeing a pediatrician or oral medicine specialist is advised.

If you are pregnant your doctor may gradually decrease the dose and stop it and may prescribe an alternative anti seizure medicine which is safe during pregnancy. Sudden withdrawal of antiseizure medication may precipitate seizures in a pregnant woman which can be dangerous for the fetus. Medicines are prescribed during pregnancy only if the benefits outweigh the risks. Your doctor may prescribe you high dose folic acid 4 mg to prevent spinal cord deformities. I sincerely hope it helps.

I have been on Coumadin for 18 years due to Lupus Anticoagulant (Antiphospholipid Syndrome) and several DVTs. In 2005 had MI with occlusion of the LAD artery and had drug stent inserted and I am still on plavix. My doc has debated when to take me off the Plavix safely....what are the recent studies about this dilemma? thanks so much!

Phenytoin and gingival hyperplasia

Common Questions and Answers about Phenytoin and gingival hyperplasia

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