Phenytoin gingival hyperplasia
Common Questions and Answers about Phenytoin gingival hyperplasia
dilantin
Taking the drug with food may reduce some symptoms, however, clinicians should keep in mind that oral administration with continuous nasogastric feedings can significantly impair phenytoin bioavailability. Gingival hyperplasia is a adverse reaction in children and young adults, especially during long-term therapy. Emphasis should be placed on good oral hygiene and gum massage. Cataracts have also been rarely reported after long-term therapy.
Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..
The antiepileptic drugs need to be checked for a dosage modulation, assessment of adverse effects due to chronic usage over years like megaloblastic anemia, gingival hypertrophu and osteomalacia with phenytoin.
Take care.
Hi everyone,
I'm new to this community.
My neurologist just informed me that Osteoporosis and shrinkage of the Cerebellum are very serious side effects for long term users of Dilantin. Does anyone know more about this?
I've been taking 500mg of Dilantin for over 30 years since I was a teenager, and now I'm terribly worried. Not one of the neurologists had mentioned anything about this over the years, and now at 46, I've learned that I may have severe osteoporosis.
Adrenal gland problems like adrenal tumors, congenital adrenal hyperplasia, Addison’s disease or Cushing’s syndrome also result in excess hair. At times the hair follicles are very sensitive to androgens in blood. This results in excess hair. Disorders of endocrine glands like pituitary, thyroid too cause this problem. It could be due to the higher testosterone level. The other possibility is that you have excessive body hair or hypertrichosis.
Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..."
It however says that initiation of Folic acid and phenytoin together is beneficial.
Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
There are gingival (gum) graft procedures that are successful. The tissue is often taken from the palate.It is possible in the future that this type of tissue can be genetically grown(for a better word).
What are some treatment options for gingival embrasures? They have become more prominent since I did deep cleaning last year.
Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm
Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.
but when i was brushing my teeth, i had a gingival bleeding. my teeth blood was out. if my chopsticks really touch the hiv’ blood or other body fluid and then i had a gingivai bleeding. will i get hiv? i am afraid. my English is poor. can you understand my words? i am really afraid now.
Hello AB, welcome to the medhelp forum. Phenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes.
hi,you need some monitoring of phenytoin(eptoin) blood levels as valparin causes increase in blood levels of eptoin,which is responsible for gingivial hyperplasia(gum swelling).
Valparin and topirol both are associated with mental problems.
For gum swelling,best is to either reduce the dose of eptoin and maintain oral hygiene(drugs like azithromycin,isotrentoin and surgical procedures are being used for treatment)
In your case,dose adjustment based on eptoin levels will help.
Sudden onset of generalized gingival swelling in young children is commonly associated with primary herpes infection. Seeing a pediatrician or oral medicine specialist is advised.
During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
Dear Madge - I am scheduled to see a breast surgeon tomorrow and hopefully will finally learn how we are going to proceed. Although I have taken histology, I could not give you a good answer to your question after all these years. I felt it was a term that I needed to relearn in case I see this on my pathology report. I retrieved this from the cancer.
Atypical hyperplasia is a precancerous condition that affects cells in the breast. Atypical hyperplasia describes an accumulation of abnormal cells in a breast duct (atypical ductal hyperplasia) or lobule (atypical lobular hyperplasia).
Atypical hyperplasia isn't cancer, but it can be a forerunner to the development of breast cancer.
Do not use mouth wash right away wait about a week and stick with warm salt water rinse. The warm salt water rinse the salt water promotes healing of the gingival tissue. Mouth wash can be to harsh. And yes you should still brush you want to keep your mouth as free from bacteria as you can during healing. Food in between teeth, flossing. Always floss.
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