Phenytoin suspension conversion
Common Questions and Answers about Phenytoin suspension conversion
dilantin
As there is peripheral conversion of androgens to estrogen in these patients, this is the same mechanism as polycystic ovary syndrome, PCOS.
Use of drugs like Tetrahydrogestrinone
Adverse effect of Phenytoin"
Wikipedia - Hirsutism [Hirsutism or frazonism[1] is the excessive hairiness[2] on women[3] in those parts of the body where terminal hair does not normally occur or is minimal - for example, a beard or chest hair.
In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780]
Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.
Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..."
It however says that initiation of Folic acid and phenytoin together is beneficial.
Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
The efficacy of oral hypoglycemic agents and insulin may be diminished by certain drugs, including thiazides and other diuretics, corticosteroids, estrogens, progestins, thyroid hormones, human growth hormone, gonadotropin-releasing hormone agonists, phenothiazines, atypical antipsychotics, sympathomimetic amines, protease inhibitors, phenytoin, megestrol, danazol, isoniazid, asparaginase, pegaspargase, diazoxide, temsirolimus, sucralfate oral suspension, as well as pharmacologic dosages of nic
Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm
Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.
Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..
Hello AB, welcome to the medhelp forum. Phenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes.
During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
I totally forgot to tell you that he is on Phenytoin 100mg once daily. Can this be continued and taken for a long period of time?
Thank you doctor once again for your immediate reply.
Addition of other antiepileptic drugs like phenytoin,lamotrigene and sedatives will be helpful for controll of his night symptoms.
Teak I like how you do not sugar coat man and stick to the facts which you seem to know quite well. From everything I've read a 14 week should put me in the clear but I can't shake this fear of sub strains and delayed conversion. Just to know though are the tests licensed to detect the more rare strains?
* After excessive posting, a warning will be issued by MedHelp
* Continuing to post regarding the negative result / no risk situation will result in a 3 day suspension
* Continuing to post upon your return will result in a permanent ban.
what is the newest type of bladder suspension tx?
This discussion is related to <a href='http://www.medhelp.org/posts/show/225945'>What is the best bladder suspension surgery?</a>.
Is it possible that my frequent UTI problem is due to my recent bladder suspension and rectal repair surgery?
I had a bladder suspension 6 years ago and to my knowledge I had no problems up until now..
In the last 3 months I have had 2 severe bladder infections to the point where my blood pressure went super low.
this last one put me down for 3 days..sleeping body aches fever etc. I have never been a sickly person so I question if the suspension could be the problem.
A few weeks ago I woke up with yellow crust on the corner of my lips and it went away in 2 days, and today I woke up and it's in the exact same spot again except a little more then before. It doesn't hurt or itch, it feels like my lips are very very dry. I don't smoke, I have grandmal seizures and my medication is phenytoin and kepra but I didn't read anywhere that would be a side effect so I'm worried this could be a STD or something.
Recommended
