After some considerable amount of reading, I have come to the conclusion that one of the best of this group of medications is Prilosec (
omeprazole). I did once give this drug a poor rating, but recent evidence suggests it's actually proving to be one of the safest and most effective. As with all meds, there are potential side effects and a specific contra-indication when liver failure is evident, but other than that, I have no hesitation in recommending it for CKF dogs.