The first couple weeks, I was so nauseous,and had the upset stomach
horrible! I gradually lost my appetite, and therefore have lost some weight, which is another reason Metformin is given. It's really a diabetic medication as well, so make sure to check your sugar occasionally, like if you get the shakes or something. After a few weeks, and increasing to 3 times a day, it finally bought on my period, and it was only for about 5 days, and the cramping wasn't as bad either.