Ibuprofen and liver disease

Common Questions and Answers about Ibuprofen and liver disease

ibuprofen

Hi all so far 3 months into treatment i was pretty much sailing through it but not by body is hurting my back my legs just everything i ran out of Acetaminophen and want to know if anyone here knows if i can take Ibuprofen for the aches i am undetectable at week 4 no liver damage if someone could help me out with this Thanks Much love Karen

Just want to say how 800mg of ibuprofen is helping me. I feel very rough on a daily basis. So far, with the ibuprofen, the change in the roughness is dramatic. Helps me function for about 4 hours. Only doing one or two a day. BTW, I am getting to know my pillow on an intimate basis lately. I didn't know I can sleep this much. Deffinatly not me. This medicine does weird things. Have courage all!!!!! Kick that STINKIN 1, 2 or 3 to oblivian.

Can using an excessive amount of ibuprofen over 30 days cause liver problems like hepatitis? I took Ibuprofen for a month (6-8 tabs a day). A few weeks after taking them I had fatigue, nausea, joint pain. It went away in about three weeks. I was also taking Levequin at the same time. Could this have been from the medication?

I have Hep C, been treated 4 times can't get rid of it, I have last stage Cirrhosis, am going to need a liver transplant before long, this can be taken safely with liver disease and hepatitis.

Acetaminophen has predictable hepatotoxicity and affects the liver in a dose-dependent manner. In patients with chronic liver disease who have pain symptoms, acetaminophen can be used safely in a dosage of no more than 2 g per day. That’s the equivalent of four extra-strength (500 milligrams) tablets per day or 6 regular strength (325 milligrams) a day.

The reason the childrens chewables are not recommended for adult use is that there are many medicial conditions that exist in adults, and not in children, in which it could be DANGEROUS to take ibuprofen, e.g. peptic ulcers, high blood pressure, heart failure, serious kidney or liver disease. In other words, rather than list a host of "dont take this medicine if you have A, B, C.......

Ibuprofen is strictly contraindicated for those who have decompensated liver disease. And encephalopathy is always 100% reversible using current regimens, which do not carry the associated risks of ibuprofen. If it could be shown to help recovery from encephalopathic coma (50% mortality rate) it might be worth the risk in this setting. Perhaps that research will follow. Thanks for the article.

lifted entirely from liverdisease.com: One of the most common questions that I am asked by my patients with hepatitis or other liver diseases is - "Which type of painkiller is safer for my liver - acetaminophen (Tylenol), or nonsteroidal anti-inflammatories (such as Aspirin, or Motrin)?"- Well, in this brief article which is excerpted from my book : "Dr. Melissa Palmer's Guide To Hepatitis and Liver Disease" I will answer this question.

is needed and because my liver enzymes, chemistires wre within normal range, I did not have advanced liver disease and was able to loterate the treatment better if I took tylenol/ibuprofen for cramps the benefit outweighed the risks...many of the statistics and people I have spoken with who did not complete the treatment cited the horrible aches, pains, fatique as a reason...

However the PA from the study told me that Tylenol is the recommended pain reliever for those with liver disease as long as no more than 2 grams are consumed within a 24 hour timeframe. Since Tylenol does nothing for me, I'm sticking with ibuprofen.

I'd also like to correct the statment, above, that Ibuprofen is not metabolized by your liver. NSID's, like Ibuprofen, are metabolized by your liver: "...NSAIDs are metabolized by the liver via oxidative and conjugative pathways and have the potential to cause liver injury, with some agents being more hepatotoxic than others" Source: http://www.uic.edu/pharmacy/services/di/liver.htm "...

All my previous hepatologists have steered me towards ibuprofen, because of the liver toxicity risk associated with acetaminophen. However, my doc has told me to definitely switch now to acetaminophen. My recent biopsy shows advancing liver disease due to hep c, I'm now stage3/grade3. My doc says that as liver disease advances, the risk to the kidneys from ibuprofen exceeds that to the liver from acetaminophen.

I trust you are seeing a gastroenterologist (digestive disease doc) or hepatologist (liver disease doc)? We can't diagnose anyone based on fatty liver disease and two blood levels. Your doctor knows your medical history and the extent of your liver disease. We don't. It is the job of your doctor to explain what these test results mean and what is causing them. They are many conditions and illness that can cause these blood levels to be high besides liver disease.

If it is then a nutritional approach to correct this can reverse the course of fatty liver disease. You must limit intake of refined carbohydrates. Avoid the whites and eat whole foods such as organic fruits and vegetables, animal products, nuts, beans, and seeds. it is important to drink enough water. liver disease is not a benign illness. It occurs primarily due to lifestyle choices and can be reversed with a safe and effective holistic plan.

I'm wondering what is an effective painkiller that is safe to take for liver disease. My pharmacy suggested Tramadol. What say you people ?

Acetominophen has less total lifetime dose restrictions but we recommend less than 3 grams daily for standard patients but much less if they have liver disease. Hope this helps!

Soaper, I did a quick look-up on Fosamax. I didn't see liver problems mentioned (maybe someone else here can find some additional info for you). I'll paste here what I did find on Fosamax: *************************************************************** The following came from Medscape: http://promini.medscape.com/drugdb/drug_patient_handout.asp?

However if your Dr. feels like you are close to decompensating (End stage liver disease) s/he may want to play it safe and wait. The important thing is that you have a Hepatologist who is monitoring your condition. You might ask for a second opinion if you really believe you can handle it but I tend to trust the Hepa on this and I am not one who trusts Drs., in general. Good luck to you and stay tuned for more in depth replies.

I've heard that none are safe for the diseased liver. Is this true? Fevers, joint pain....I dont know which to use. The doc said pick one. I'm not sure what to think of my doc.

Osteo arthritis, wore out the padding dancing the jitterbug. Is taking a couple Ibuprofen going to cause an liver damage? I'm thinking about 4 a day for a week while I am at a ski camp in Colorado (my last hurrah before treatment). I am scared to death of doing anything to ruin my good status with this desease.

A "real live educated doctor" told you the only nsaid you could take was Ibuprofen because the others "eat your liver like pac man?" And they also "kill your heart"? And therefore only opiate laced Tylenol is what's required for long term pain relief associated with IFN/riba side effects?? Tell me sambone, was this doctor from Earth or was he a specialist in Martian physiology? That matters, you know?

Check this out. Not sure if this one has been posted here before. This has to be the most exciting data I have seen about liver disease & coffee use. Specifically saying people with HCV will respond to TX much better if prior coffee drinkers. http://hepatitiscresearchandnewsupdates.blogspot.com/2011/03/coffee-boosts-hep-c-treatment-response.

I went to the doctor today but he thinks it might be some form of rheumatoid disease and gave me Ibuprofen. I have not taken any yet. Since he wasn't sure what it was, I don't know if I should. Can you please tell me what you think it might be.

I have end-stage liver disease and I get severe hand cramps and what over the counter pain reliever can i take without it counter acting with prescribed narcotics

The Liver Center at Baylor College of Medicine is one of the best places to go in the country for patients with liver disease. I would go there and have them evaluate your liver disease and help you to manage your liver disease now and in the future. Hopefully you will be able to cure yourself of the hepatitis C virus which is damaging your liver. Good luck with your treatment! Cheers!

Elevated levels can occur with liver disease, but other causes for the enzyme elevation could be muscle disease or injury. Some medications can also raise these levels. Discuss these options with your consulting doctor. Hope this helped and do keep us posted.

I have been fighting fatigue and pain for a couple of years i have had many test and it was found my liver enzymes test were high, to keep this short many tests followed my numbers flucuate from 160-707 up and down month to month my last test was 707 I have been off any meds for months now doctor can't explain it. All other blood test normal get to go for liver biopsy tomorrow specialist dosen't want to wait any longer.

I hope your doctor returns soon so you will know your true liver disease status. Hang in there! Try to be patient...I know it is hard.

I had a 24yr transfused infection, went into complete liver failure, 9-12-2001, crossed over, came back. 2wks later, tested for hep c. My doc put me in a study that paid for all meds (peg-infr-riba) and I cl@4wks, now SVR 11mo-2b. I'm still ESLD (end stage liver disease) & should be on a transplant list. I'm now 20 mo past my est. death date. And feel great! I handled all sx w/otc drugs , herbs, nutritional suppliments diet and exercise, meditation and marijuanna.

Dan on Saturday, February 03, 2001 Dr. Steve, Opiate addiction is a disease and needs to be treated accordingly. Opiate addiction is a disease much like diabetes. A person takes insulin to maintain proper levels of sugar in their bodies. A heart patient takes digoxin to maintain proper heart functioning. An opiate addict may take LAAM or methadone to restore an imbalance in their brains due to the disease of opiate addiction.

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