Effexor and liver damage

Common Questions and Answers about Effexor and liver damage

effexor

If you look back at the history of benzodiazipines and the damage they caused (and still do)it seems to me to be wise to be cautious with all theses drugs. Put the name Peter R Breggin into your search engine and take a look at the current class actions being taken out with regard to varioss ADs. No i dont think you are being paranoid. The careless prescibing of drugs has done untold damage and we cannot trust major drug companys to always show the kind of responsability we might expect.
I will take the withdrawl when that time comes and pay the piper. Many people complain about Effexor and it's withdrawl, but you never hear them talk about the 4 years of normalcy that it provided them. Everything worth anything comes with a cost.
I just wrapped up 41 weeks of treatment (VX prove 1 participant) and I was on lexapro (which didn't work) and then effexor. I didn't think the effexor worked really either, it certainly wasn't all rainbows and chirping birds anyway. But as I tried to withdraw from the effexor I dropped down from 2 pills a day to 1 pill a day for 10 days, and then 1 pill a day for 10 days, and then 1 pill every other day for 7 days, and then 1 pill every 3 days for 7 days, and then finally 1 pill every 4 days.
Maybe you really need just an adjustment in the effexor up or down ? I've tried Paxil, Zoloft, and Prozac, and I know effexor is tough to start, and tough to stop, but maybe you need it. My daughter had problems cutting back on zoloft when she was pregnant, but she was able to take a lower dose all the way to the last two weeks, and both her and baby are fine. I hope you feel better, if you need to talk, I'm here to listen.
And 550 mg is a very high dose for seroquel ask your doctor if there are any other medications you can be put on that wouldn't hurt your liver as bad. I know that lithium bypasses the liver and goes right to the kidney.. I hope I helped.
Hi, I have been on Effexor XR for 3 years and I have gained about 40-50pounds, most when my dose was increased to 225, now I am on 75mg b/c I'm getting ready to wean off the medicine in a couple of weeks,and I haven't lost anything yet. My eating habits have not changed and I exercise. I have always been underweight and I could eat whatever I wanted...I'm only 26 years old...I know my metabolism has changed some, but not enough to pack on 40 pounds.
i don't know whether you take antidepressants. i do and i am on effexor and i have fatty liver caused by effexor xr. I don't drink alcohol and iam only 26.
And when I wanted to get off of it I had the worst withdrawals from it. I have a friend who also got major liver damage from it.
i have thought of suicide all the time; for 12 years or so.....I also have major liver damage and as of a few years now serious MIGRAINES that are unexplained....... I say we all need to use this internet to find out for ourselves about these crazy drugs THEY want to give us. wether it is ZOCOR or Lexapro. etc.., and for this person above ..JOSS26....... you are going to be in worse shape in a decade if you don't take control of YOUR OWN LIFE NOW..
I had been having extreme pain that started in my stomach and seemed to travel up into my rib cage area the pain was extreme and I would find it difficult to breath and often experience tingling and loss of feelin in my hands and feet. This pain occurred rarely but has continued since the birth of my daughter in 1999. I went in to the doctor when after one of these episodes I did not feel well for several days. I had been taking new vitamins recommended by a pharamacist for fatigue.
I have been on Effexor xr for 4 1/2 wks. It has done nothing for my anxiety and actually feel worse now agoraphobic. They had me up to 150mg which made me feel unreal and out of it so they put me back down to 75mg. I know its not right for me the side effects are too bad. My question is how to get off I am so scared of the withdrawl symtoms. I have had every s/e on it including confusion muscle tension dizziness insomnia agitation to name a few so will the withdrawl symtoms be worse.
my viral load was undetected 8 months post treatment, and my liver test have been normal 18 months post treatment. My liver biopsy was Stage 2, Grade 2, with signs of beginning stage 3. I was genotype 3a. Now my question, I have been taking Trazodone an anti-depressant. It has been working well, I have more energy and a desire to do things, it helps me stay active. The problem is that there is a warning on about possible liver damage, and to use caution if you have liver disease.
You also don't indicate whether you tapered off the Effexor, or were just switched to Zoloft. Effexor is known for being very difficult to quit, and so it is best to slowly taper off it. Switching to Zoloft, a medication in a different class, won't necessarily do anything about Effexor withdrawal. As for long term damage, that's a sore spot for medical professionals, because yes, it can happen, but usually only when mistakes are made by the doctor, and it's not very common.
i have been on 225 of effexor and it has helped me alot but the weight gain has been horrible. i crave carbs and feel hungry alot. but i tried goin off the effexor and had bad bad withdrawls. i took my time too. any ideas?
//cholesterol.emedtv.com/zocor/zocor-and-liver-problems.html _________________________________________________________ It may be the combination of meds...(Zocor&Suboxone)...I couldn't find any info on effexor xr and elevated liver enzymes. Hope you get it figured out.
I do want to reiterate that around here the gi docs do recommend a daily reimen of milk thistle which is a prevents and treats liver damage...I recommend all patients with hepatitis, hx of drinking, current drinking or exposure to toxic chemicals...if you want further info john has theresearch data...my hep c patients are all on it, often have been since diagnosis..
I am the only person who has gone from 300mg/day of effexor xr, to NOTHING. Everything that was described by other posters is accurate and im sure it depends on the dose and frequency and individual to see how bad the symptons will be. I tapered down from 300 to 150mg a day using 37.5 mg pills. Then in 1 week I went from 112.5 down to 0 mg a day. This drug is evil, every doctor should experience the withdrawal of this drug prior to prescribing it. I am a huge tattooed, gun toting BOSS.
My doctor assured me that Effexor was non-addictive, and posed no suicide risk. Now I am reading that Effexor has been linked to addiction and suicide! I think the limit is small claims court in my state is $3500. At least I could go thru a supervised withdrawal. I would be afraid to go cold turkey. I hear you can get angry and suicidal. Also, I now have a costly drug habit of $5 a day, and I only get $610 a month social security.
Even things like antidepressants can (in some people) cause liver related side effects - i/e increased enzyme readings due to cell damage. Both the liver and spleen are in concert with many problems and they can both swell. Next would be to have a series of ANA (Anti-nuclear antibodies) run, and have ferritin/TIBC checked as well as ceruloplasmin - Those detect/rule out things like PBC PSC Wilson's and Hemachromatosis - All of which are able to cause a type of (non viral) Hepatitis.
Here is some information on Ativan and other benzodiazepines. Also SSRI antidepressant. They are all excreted through the liver, and all have a warning for people with Liver diseases. You need a good Dr. to work with you on which anti Depressant to use also which Type of drug to use for anxiety. For anxiety Xanax and Clonopin are the preferred Anti Anxiety drugs, as for the A.D.'s I had a hepatoxic reaction to Lexapro and Zoloft, so you want to be-careful there.
anyway, just want to post this on some medical sites, and I know some of you are suffering, or know someone who is suffering from liver cancer, etc...anyway, I know some people who are...just was watching Extra (yeah, I'm busted, lol) and I saw this piece about this Dr. Julien at Cedar's Sinai in Los Angeles who has a revolutionary new treatment for these cancers, as long as the tumors are relatively small. The treatment takes about 12 minutes and the recovery time is about an hour...
I suffered serious depression the first and second time, first was plain old inteferon which I stopped mid course, second time was on Pegaysus and lost it, GI put me on Effexor and I did ok after that. Now I have relapsed and asked to go back on it before I started infergen. I had also read or hear that Welbutrin was not a good thing for the liver? Has anyone heard about a study concerning weight based treatment? I heard a brief thing on tv that it is better for relapsers?
tried wellbutrin felt ok for first 2 weeks then definitely felt it messing up my liver. Need my brain to wake up and reduce pain. i am also taking prednisone. high rhumatoidal factors since doing the treatment for 11 weeks in 2005 before stoping. Those 11 weeks created more problems for me. thyroid and low cortisol. unable to create acth. now i am in a steroid night mare. pretty desperate when you know how really bad all this stuff is for you especially on top of hep c.
Dieterich has authored numerous journal articles, abstracts, and book chapters on viral hepatitis and AIDS-associated infections of the gastrointestinal tract and liver, and their treatment. He is an internationally-recognized expert on hepatitis C infection and is involved in several research programs evaluating the management treatment of chronic hepatitis C virus (HCV) infection and co-infection with HIV/HCV. --------------------------- Dieterich doesn't know what he is talking about?
Hi Therese Well done it's not easy your patience has paid off and hope mine does too. I came off effexor cold turkey in May 2010 Gp's fault and am now weaning off dolsulipin should be off April 30th 2012 with any luck. Have you had to rediscover yourself and reassess people who are around you etc? Thers a feeling of being reborn and of waking up after along sleep !
It turned out to be high blood pressure caused by a combination of the antidepressant Effexor and the Interferon and Ribaviron. My G.P. put me on Toprol which is a beta blocker and it worked wonders. No more pounding in my head while trying to sleep and no more headaches. I'm not on it any more, though, since TX is over for me. I also stopped the Effexor following completion of treatment. I just had my 6 month PCR and it was clear!!!
I have read a lot about it and this is the first time I have heard anybody say anything good about it…the side effects are horrible (personally) the constipation was ridiculous…pain never went away… and my depression got worse….switched back to Effexor XR with a higher does and I am good to go! Please read more about Cymbalta before you really get started on it…I can not tell you how many months I spend with horrible stomach aches! YUCK to CYMBALTA!!!!
But we watched my husband's best friend die from liver failure last year, and that was scarier (albeit alcohol cirrhosis, not hepc, so I could tell myself not to worry). And now my Mom and my Aunt's sudden cirrhosis and now liver cx, (which I really thought would never happen), has me REALLY scared. <<Wellbutin is for mild to moderate depression, and you may require stronger drugs, or a combination of several drugs>>.
How long have you been on the effexor? Give it a while before you adjust effexor....and let your Doc adjust it (I cant stand effexor personally - but we all react differently) Check out the Thomas Recipe and Amino Acid Protocol links listed in Health Pages here.....they work....good luck!
for sleep and trazadone. i believe trazadone and effexor can be mixed. i only use low dose 25 mg a nite and i mix it with other sedative drugs still. sometimes i use a little phenergan(prescribed for nausea during tx.) or zanax. ive just heard theres a new drug out- the same as tylenol PM without the tylenol at walmart. from others ive spoken to trazadone is good for sleep. although i still have vivid long drawn out dreaming.
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