Both contain synthetic compounds similar to natural cannabinoids and found to be effective for
. In the US I believe Cesamet is approved by the FDA for
chemo induced nausea but not for
MS pain, so it may not be easy to get access to it. And as far as I know, Sativex isn't approved in the US.
In US states where it is legal, natural may be the easiest to get, and perhaps is preferable to the pharmaceuticals.