Aldara for melanoma

Common Questions and Answers about Aldara for melanoma

aldara

Is Aldara use a good idea for someone with autoimmune disease (for possible facial pre-melanoma in area difficult to operate on)?
The US FDA also does not officially approve its use for melanoma or pre-melanoma (lentigo maligna). Its use is approved for basal cell skin cancer and actinic keratosis, a precursor condition of squamous cell carcinoma of the skin. At present, the best evidence for the use of imiquimod for melanoma or lentigo maligna are only case reports. While the results of these studies are promising, only a few patients have been studied and the quality of evidence is weak.
html?WT.ec_id=NCOMMS-20130305 Aldara is a cream used for topical treatment of non-melanoma skin cancer, and is thought to act through stimulation of anti-tumour immunity. The active ingredient, imiquimod, has been shown to stimulate toll-like receptor 7. Aldara also induces psoriasis-like lesions when applied to naive murine skin, and as such is used as a mouse model for psoriasis. Here we find that in naive murine skin, Aldara induces inflammation largely independently of toll-like receptor 7.
If for example, your are diagnosed with a melanoma skin lesion and the doc says to apply the aldara 1x/day every other day for 3 months. During this time, if your skin reacts violently in that area and perhaps beyond where the original lesion was, then your immune system is in over drive and will successfully clear the cancer in the area of the reaction. If there is no reaction, then there was nothing to attack.
That, too, was unsuccessful so she has retreated to rxing Aldara. I know it is not indicted for squamous and am wondering if I am wasting more time and should ust go ahead and have the Mohs on my nose. Is trying Aldara for squamous worth trying for the next 3 months?
Hello. I've attached a photo of a skin coloration on the base of my penis (the photo is a collage at various resolutions). The area is about 1/4" wide and high, is asymmetrical and brown in color. I first noticed this spot about 6-7 years ago (2002). Fifteen (15) months ago I showed my dermatologist, and upon clinical observation, he said "this has to be removed" and referred me to a urologist.
org/posts/Dermatology/Treatment-Course-for-MisDiagnosis/show/1130063 This is a photo of a skin coloration on the base of my penis (the photo is a collage at various resolutions). The area is about 1/4" wide and high, is asymmetrical and brown in color. I first noticed this spot about 6-7 years ago (2002). Fifteen (15) months ago I showed my dermatologist, and upon clinical observation, he said "this has to be removed" and referred me to a urologist.
1. What is the chance that this lesion was HPV related? I have never had any lesions or warts of any kind in this area. 2. If not HPV, what other reasons as I am a non-smoker, maybe genetic predisposition? 3. If this is HPV related, is this a common area for HPV lesion about an inch below waistline close to right v fold? 4. If this is HPV related, what is my chance of recurrence since the lesion had been present for ten years and if I have immunity from this first lesion now. 5.
Lets say they are cancerous/melanoma, for the big one and from the physical aspects of it, does it pose any risk to my survival at this point? I know that the bigger the tumor growth, the higher chance it will spread. 3. What kind of Dr should I see, a dermatologist? Would they have to biopsy it first? 4. If I need to get it removed, how will the surgery procedure go down? Is it a one man job? How long will it take? Anything else I should probably know? Thanks!
oh i see, to my experience moderate sun is much better, at least for skin color in sothern italy since we have almost zero melanoma risk skin can produce very high amounts of vitamin d but i have to use both sun, suplements because it does not increase more than 30ng/ml (i just reached 47ng/ml by supplements and 1hr un exposure everyday).
Imiquimod 5% cream (Aldara) is licensed for the treatment of anogenital warts in immunocompetent patients. The evidence supporting this license comes from three prospective, double-blind, randomized, vehicle-controlled trials.22–,24 In these trials 698 immunocompetent individuals were randomized to receive topical therapy with imiquimod 5% cream, 1% cream (22,,23 only) or vehicle control. The topical treatment was applied daily22 or three times a week23,,24 for 16 weeks or until lesions cleared.
Thanks for the info frank, did you also use aldara on your genital warts? I have it now, and doctor told me to apply it twice a week for 16 weeks, i hope these genital warts would be gone soon, I have a question, if these warts are gone, is still there any chances to infect your new partner? I am new to all these, I hate that I trusted the wrong one before. I felt like dying inside having these sufferings.
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