I've recently had colposcopy biopsies. The Lab reports came back high grade squamous cells, Vain III. I really dont understand it, but evidently the bad cells are thru 3 layers of the vaginal wall. My dr prescribed Aldara vaginally, twice a week for 12 weeks. I've had my 4th treatment, and I'm not having fun. Within 24 hours after teatment I am crying in pain, muscle aches, joint pain, my skin over my whole body hurts. I also have vaginal itching, burning, but its not that bad.