I have macrocytosis and my serum B12/folate levels are normal to high. However, I am showing signs of B12 deficiency with numbness in my hands and feet and pain in my legs. Is it possible to have a B12 deficiency and still have normal to high serum levels of B12?
I have been going through blood tests for over a year trying to find a cause for my macrocytosis! After my genereal physician and now hematologist number 2, we are still looking for answers. He suspects hyperthyroidim and I was hoping someone could help me and give me another opinion.
Here are my latest test results.
T4 total 12.7
T-Uptake .73
Free Thyroxin In 9.3
TSH, High Sensitive 4.272
Other abnormal results include MCV 103.2
RBC 3.76
Hct 38.8
MPV 6.5
Retic Count 2.5
Retic Absolute .
my sis is 28 years old her Hb is 4 her smear examined shows decrease in the RBC COUNT, moderate degree of hypochromia, moderate degree of microcytosis and mild degree of macrocytosis ,many ovalocytes,tear drop cells ,target cells and schistocytes are also seen now what to do?
I am eating zidovudine and lamivudine !and I am a smoker so i just wanna know smoke will influence medicine or not?
Hi
Enlarged red blood cells is called as macrocytosis. It is caused by a lot of factors such as deficiency of vitamin B12 or folic acid, liver disease, alcoholism, medications (anti cancer drugs) etc.
Do write in if you need more information.
I ate lamivudine and zidovudine at 22 hours late after the behavior.Does it will work well?
I was given Epivir, Viread and Zidovudine.
Depakote can also increase levels of other drugs in the body, including diazepam (Valium), ethosuximide (Zarontin), warfarin (Coumadin), and zidovudine (Retrovir). Talk to your doctor before taking these medicines with Depakote.
After investigation, the doctor prescribed PEP for 28 days. The tablet name is DUOVIR (Lamivudine 150MG/Zidovudine 300 mg). The doctor told to take "half tablet" in the morning and "1 full tablet" in the night.
When I read the leaflet inside the tablet, it is written that it should be given to adults or children over 12 years of age. It is mentioned that it should not be given to children below 12 years of age.
My son is 7 years old. I don't know what to do?
Since that time, he is receiving HAART with lamivudine-zidovudine-efavirenz twice daily, but he told me that there are some days ( at maximun 3) that he does not take the pills, but most days of the month he is adhering to the treatment. His current viral load is 39,000 copies/ml.
When I realized of him diagnosis, I went to a doctor who gave me profilaxis about 18 hours post-exposure with lamivudine-zidovudine.
my regimen was Zidovudine+Lamivudine+Aluvia, i mean, i missed one dose of Zidovudine+Lamivudine+Aluvia...you mean I should add one dose more on the end?
1 - would PEP be effective even if the source has a high viral load?
2 - After the 28 days, can I drink alcohol?
Thank you very much in advance, I am quite distressed about it.
No Risk in a "Prick" alone. HIV is transmitted via INJECTION from needles not pricks. You should have still reported this and followed the hospital rules for this type of event.
I performed oral sex on a guy that I later found out has HIV. I certainly swallowed a bit of his cum during the oral sex and the next day discovered he is taking Atripla (medicine for hiv treatment which is said to reduce the viral load to undectable in most cases).
I freaked out and bought lamivudine/zidovudine 150/300mg as a preventive measure (I'm travelling so that was my option). What are my risks? Am I overreacting?
Dear Doctor
I am straight male 28 years old. On may 20, I had one possible exposure with involve with broken condom with KTV girl in Cambodia. I asked the girl about her HIV status she replied to me, "I want you feel scary for couple months". I told my friend about incident then he went to ask the girl to test and it came back negative. 12 hours after incident I was prescribed PEP for a month.
Enlarged blood cells (macrocytosis) is shown up on a lab test with elevated MCV (mean cell volume). Optimum MCV values 87 to 92 cu. microns. A vitamin B12 serum range under 550pg/mL (405pmol/L) would be a confirmed vitamin B12 deficiency in Japan and most countries in Europe.
Hi,
You see Vitamin B 12 deficiency can occur without any significant anemia and with a normal CBC. However, the RBC’s are larger in size which is known as macrocytosis.
There are some tests which can pick up Vitamin B12 deficieny before actually the anemia develops. Diagnosis of vitamin B12 deficiency is typically based on measurement of serum vitamin B12 levels; however, about 50 percent of patients with subclinical disease have normal B12 levels.
sir,
i went to prostitute and used condom while doing sex with her. at that time on my right hand's middle finger, there is a 24 hour old small abrasion of 1cmx1cm which was not bleed, and i removed the condom with my right hand. then i feared that the hiv virus may enter through the abrasion. i don't know whether she had hiv or not. at the 14th hour of that exposure i started PEP with zidovudine and lamivudine. on 15th day of PEP course, i missed two doses and then completed in 28 days.
combivir is adeqaute depending on your risk, most doctors prescribe this, it is the standard regimen, it consists of 2 drugs, lamivudine and zidovudine. PEp is a combination of 2 or 3 drugs which can reduce the chances of hiv infection by up to 85%. If you want more u can get more, but in most low risk encounters like yours combivir works just fine.
t know yet if there is a connection but blood tests have revealed Macrocytosis.
I went to a clinic and startednPEP (Zidovudine, Lamidovudine and Epivir), the nausea and vomiting has been really bad, also some diarrhea, but i am dealing with it. But today on day 17 of the Treatment I started running a low temperature, 37.5C / 99.6F, also i feel some enlarge nodes, that might have been there before, but not sure.
I am quite scared as the fever started sudden and with no other symptoms of illness.
Recommended
