vioxx was pulled from the market by merck as a result of

Co has been subpoenaed by the US Department of Justice as part of a criminal investigation into marketing practices for three prescription medicines. The products in question are Temodar (temozolomide) for brain cancer and hepatitis C and cancer drugs PegIntron (pegylated interferon alfa-2b) and Intron A (interferon alfa-2b), according to Merck's just-published quarterly report. All three of the drugs were acquired when Merck bought Schering-Plough in 2009.

I was given vioxx years ago, read the warnings about heart attacks and such, and threw them all in the trash! Not much later it was pulled from the market. If I lost a loved one, $$ isn't going to bring the back anyway, it's all stupid. If I do myself in, I guess I will come back and haunt the manufacturers....BOOOOOOOOOOOOOO...........

they are getting ready to fight for the big piece of the pie by joining forces....its as plain as the nose on Michael Jacksons face...

They are expected to come to the market at similar times and be widely used, creating a market share battle. Merck said in early January that it was granted a six-month review; Vertex is getting a similar review and expects a decision by May 23. Many on Wall Street believe that clinical trials show Vertex's telaprevir is the preferable drug, although Merck's Chief Executive Kenneth Frazier has repeatedly stated his confidence in boceprevir's prospects.

The article is from an opinion column. I was in a boceprevir trial and the rumor from the medical people in the trial is that boceprevir will come out but Merke has back-burnered narleprevir (Schering's second PI that was just about to finish it's phase 2). Merke feels like their phase 2 PI is better so they dropped the narleprevir. All is just rumor and conjecture, as is any certainty about which will get to market first, Boceprevir or Telaprevir.

does sweat contain hiv virus,i was in a market,it was noon,suddenly a man hit me up ,his sweat came on my hand,any risk.........

you repeatedly hear that it is safe when taken as directed. The amounts of aspirin needed to act as a blood thinner are on the order of a half aspirin a day. I just saw that they were linking aspirin use to lower cancer rate w/ gastro type cancers and wondered what the effect would be in advanced staging and issues that pertain say cirrhosis. I was aware there could be some negatives and I think it's good to see your article along with the one I posted.

Years ago, she gave me Vioxx, I read the warning leaflet and threw the pills in the trash. I was right, they were pulled off the market later on. I'm not sure about this either...

ve already started treatment or are already preparing to with Boceprevir. Merck will be looking to grab as much market share as they can in the window period while they're approved and Telaprevir is waiting to be. That's what it appears to me, based on the actions they're taking. Both drug companies will have a healthy investment made into the development of their drugs and they'll be looking to recoup.

In mid-2010, as part of the Fast Track designation, Vertex began to submit completed sections of the NDA for review by the FDA on a rolling basis rather than wait until every section of the application was complete.

The full text of the boce prior-failures abstract is available from the aasld site as abstract 216. Comparing the data there with the Merck press-release points out a couple of details left out from the glossy, good news, press release. I usually pick on Vertex for this sort of selective data fishing but it looks like Merck is just as suspect.

It was the FDA that stepped in to see if the drug was safe and was instrumental in getting better study results and getting the drug off the market. It was the FDA that issued a Warning Letter to the manufacturer of Vioxx, telling the company to stop certain marketing practices due to "false, lacking in fair balance, or otherwise misleading" claims which violated the Federal Food, Drugs and Cosmetic Act. That is the role of the FDA.

These Merck drugs should hit the market this Summer, I would think. The director of the clinical trial wrote me, and said the relapse rate of those in the clinical trials who achieved a SVR is 1%. It is worth noting that figure may change, as these meds are still so new. I won't speculate that this relapse rate will be applicable to all the new gen HCV meds such as Harvoni and Sovaldi, etc...

http://www.lifesitenews.com/ldn/2008/jul/08070316.html As Lulu said "Stay AWAY" from this vaccine. AND these big Pharma's fast -tracking this drug ,, -- being sold to young kids who are otherwise healthy,,,,YET,, The FDA takes their time approving medication for people who are hanging on to life with liver disease!. Why can't drugs for those that might be near death anyhow - be given to them??

And there were a couple small, preliminary studies a few years back that showed that Vioxx and other COX-2 inhibitors taken in low dosage (1/4 to 1/2 normal dosage, if memory serves) could help lessen platelet drop-age during interferon tx. Now, of course, Vioxx has been withdrawn from the market by Merck due to potential increased risk of myocardial infarction and stroke.

Vioxx was withdrawn from the market in 2004 due to heart/stroke issues. I doubt you can even get it, but if for some reason it id given to you, ask for something different. I know a couple of other people who have gout with no rise in uric acid. So yes, it probably is best to just go ahead and get treated if your doctor agrees. I assume you've probably already been to the doctor by now. Hope it's cleared up. That pain can be brutal!

I thought it would be a good idea for her to have the companionship of a service animal and since she was alone in the house in the country, give her company. We always had German Shepherds in the family growing up and my mother was partial to the breed, as well as myself. While visiting the breeder I fell in love with the female puppy, sister to the male my mother was going to get after training.

Subsequent data has shown the actual SVR rate was approx. 15%. This failure was a blessing in disguise, as it was one of the many criteria I had to meet to be accepted into the Merck 5172-068 clinical trial, which has apparently eradicated my GT1a HCV. Merck wants to break out the beer keg with a ND viral titer @ 12 weeks >EOT, which I have met, but I'm not ready to tap that keg yet. My upcoming 4-14 viral titer will be 3 weeks shy of 6 months >EOT.

I was very lucky to get this treatment, I dropped from a VL of 585,000+ to ND in 15 days. With a significant amount of cirrhosis however, only time will tell if I remain ND, and hopefully see some improvement in liver function. My last VL titer from 10-17-14 was ND, as it has been since August 20.

I figure the kinks are worked out of it. i was on vioxx when it was pulled off the market and they were going to put me on Zelnorm and that got pulled. Just more comfortable with the oldies but goodies.

Each drug trial and treatment requires an approval from the FDA, to the best of my knowledge. In that regard, the FDA so far as Vertex may approval a plan for treating naives, a separate plan for treating past TX failures, and I assume there is one for co-infected (HCV &HIV) as well. Right now there is a current trial for BID dosing, but approval will be based on 3X daily and at some point twice daily may see an additional application.

(GILD) said it plans to start a combination study of two drugs in a single pill to treat hepatitis C by the end of the year, putting it on track to request U.S. regulatory approval for the medicine in 2014. Gilead, which spent $10.

There’s widespread anticipation the pills will win FDA approval next year. And they could be followed by the introduction of even more new therapies, the WSJ reports...." http://blogs.wsj.

The likely reason for the difference was in the first study (ELECTRON) 44% of of patients had the IL28B CC polymorphism. The second study (QUANTUM) only had 16 percent of the patients with CC. Yes, there are many non-interferon drugs in trials. But Gilead GS-7977 is the furthest along in trials. Which is why it is expected to be the first to market. Cheers!

i kept getting soft and couldnt not get fully up because my mind was distracted by the fact that she was a sex worker. then she put the condom on and i attempted to have sex but i got soft she took the condom off continue giving me a oral sex then put condom back on attempted to have sex and i got soft inside her and when i pulled out condom was off.

Vioxx was pulled from the market by merck as a result of

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