Type 1 diabetes vs type 2 diabetes mellitus

Common Questions and Answers about Type 1 diabetes vs type 2 diabetes mellitus


Avatar n tn Several studies found hepatitis C (HCV) increases risk of Type II diabetes mellitus (DM). However, others found no or only sub-group specific excess risk. We performed meta-analyses to examine whether HCV infection does increase DM risk in comparison to the general population and in other sub-groups with increased liver disease rates including with hepatitis B (HBV). METHODS: We followed standard guidelines for performance of meta-analyses.
146021 tn?1237208487 Types of Diabetes The three main types of diabetes are type 1, type 2, and gestational diabetes. Type 1 diabetes, formerly called juvenile diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body's immune system has attacked and destroyed them. Type 2 diabetes, formerly called adult-onset diabetes, is the most common form.
Avatar n tn I haven't heard of DM preventing anyone from being listed for transplant. A person on dialysis can't be listed listed but I haven't known of HbA1c excluding anyone. I did find this article which doesn't answer your question but addresses the issue. www3.interscience.wiley.com/cgi-bin/abstract/106597450/ABSTRACT?CRETRY=1&SRETRY=0 The influence of preexisting diabetes mellitus (DM) on outcome after orthotopic liver transplantation (OLT) has not been well defined.
148588 tn?1465782409 The guideline is intended for physicians and allied health professionals and provides recommendations that suggest preferred approaches to the diagnosis, therapeutic and preventive aspects of care. While obesity is a risk factor for NAFLD, there is a very high prevalence in individuals with type 2 diabetes mellitus and progression to advanced fibrosis and mortality increases in older patients. The recommendations address NAFLD in children and adults. All quotes are from this new guideline.
568322 tn?1370169040 Insulin resistance is the major feature of the metabolic syndrome and depends on insulin secretion and insulin sensitivity. In chronic hepatitis C, insulin resistance and type 2 diabetes mellitus are more often seen than in healthy controls or chronic hepatitis B patients. Hepatitis C virus (HCV) infection promotes insulin resistance, mainly by increased TNF production together with enhancement of suppressor of cytokine (SOC-3); both events block PI3K and Akt phosphorylation.
Avatar f tn I was talking about all the talk about the virus returning to wild type and the resitance mutations disappearing in 2 years time. Tracy Swan from Treatment Action Group and Jules Levin from NATAP are experts on this subject and that is where I am getting most of my information regarding resistance and the fact that no one can say that it is totally gone unless the patient is put on drugs again. .
479244 tn?1271567259 Incident type 2 diabetes was defined as fasting glucose levels of more than 126 mg/dL, self-reported type 2 diabetes, or use of diabetes medication. National Cholesterol Education Program Adult Treatment Panel 3 criteria were used to define MetSyn and its components. After adjustment for demographic, lifestyle, and dietary confounders, hazard ratios (HRs) were estimated for type 2 diabetes, MetSyn, and MetSyn components.
1330108 tn?1333680904 521-535. 17) Gerstein HC. Cow's milk exposure and type 1 diabetes mellitus. A critical overview of the clinical literature. Diabetes Care. 1994;17:13-19 18) Kostraba JN, Cruickshanks KJ, Lawler-Heavner J, et al. Early exposure to cow's milk and solid foods in infancy, genetic predisposition, and the risk of IDDM. Diabetes. 1993;42:288 -295 19) Pettit DJ, Forman MR, Hanson RL, Knowler WC, Bennett PH. Breast-feeding and the incidence of non-insulin-dependent diabetes mellitus in Pima Indians.
Avatar m tn [6–9] Some recent data suggest that patients with chronic liver disease who also have type 2 diabetes or other components of metabolic syndrome may be at risk for more advanced fibrosis. This is especially true for NAFLD[10] and possibly HCV.
Avatar m tn A priori, persons were categorized as low-risk or high-risk for diabetes based on their age and body mass index, factors that appeared to modify the type 2 diabetes-HCV infection incidence estimates. The overall prevalence of HCV in this population was 0.8%. Among those at high risk for diabetes, persons with HCV infection were more than 11 times as likely as those without HCV infection to develop diabetes (relative hazard, 11.58; 95% confidence interval, 1.39-96.6).
1913502 tn?1330391792 Genotype 3 can be more tricky then geno 2. I have seen many more relapses with type 3 then type 2, that said RVR is about as good as it gets. If your main concern in doing 48 weeks is how much harm extending the extra 24 weeks will do to you I would not be to concern about that and would not base my decision on whether to go on just on the worry. Here in the US they would more then likely do only 24 weeks, where your from is it easy to retreat if one does relapse?
Avatar m tn Green Tea Polyphenols Improve Liver Injury of Nonalcoholic Steatohepatitis (NASH) Model Mice Expressing Nuclear Sterol Regulatory Element-Binding Protein 1C (nSREBP-1c) in Adipose Tissue T. Ueno1, 2; T. Nakamura2, 1; R. Sakata2, 1; O. Hashimoto2, 1; K. Inoue2, 1; H. Koga2, 1; T. Torimura2, 1; M. Shinkawa1; H. Nakayama3; S. Otabe3; N. Hirota3; K. Yamada3; M. Sata2, 1 1.
Avatar m tn 5% were obese, 20.0% had type 2 diabetes mellitus, and 24.6% had metabolic syndrome. As expected, significantly more patients infected with genotype 2/3 vs genotype 1 HCV attained RVR (60.7% vs 27.0%, respectively; P < .01). However, among patients who attained RVR, the SVR rates were comparable between patients infected with genotype 2/3 and genotype HCV 1 (80.0% and 77.8%, respectively).
921323 tn?1268679412 Put the money towards the health costs of the uninsured. Or, use it to fund research in diabetes, heart disease, or any of the other countless complications of obesity. But is it too early to admit defeat? If we had done the same for cholesterol medications or diabetes medications, or even smoking patches and pills, we’d be paying for it in countless ways. So is there something unique about developing medications for obesity?
Avatar m tn In a cross-sectional survey including 9841 persons, Mehta et al found that HCV-positive persons who were older than 40 years had an increased risk for type 2 diabetes mellitus higher than 3 times compared with persons without HCV-infection Insulin resistance is the main pathogenic factor in the development of steatosis in chronic hepatitis C, both viral insulin resistance and metabolic insulin resistance could be implied in the development of steatosis.
26471 tn?1211940121 Sutapa Banerjee, Kousuke Saito, Malika Ait-Goughoulte, Keith Meyer, Ratna B Ray, Ranjit Ray Chronic hepatitis C virus (HCV) infection has a significantly increased prevalence of type 2 diabetes mellitus (T2DM). Insulin resistance is a critical component of T2DM pathogenesis. Several mechanisms are likely to be involved in the pathogenesis of HCV related insulin resistance.
233616 tn?1312790796 Our data suggest that the potentially deleterious effects of metformin to AD patients may be avoided by using it in combination with insulin; the combination may result in a beneficial effect in treating both type 2 [diabetes mellitus] and in mitigating AD progression," the researchers write. AD expert Michal S.
Avatar f tn Insulin resistance is the major feature of the metabolic syndrome and depends on insulin secretion and insulin sensitivity. In chronic hepatitis C, insulin resistance and type 2 diabetes mellitus are more often seen than in healthy controls or chronic hepatitis B patients. Hepatitis C virus (HCV) infection promotes insulin resistance, mainly by increased TNF production together with enhancement of suppressor of cytokine (SOC-3); both events block PI3K and Akt phosphorylation.
Avatar m tn Vitamin D deficiency is linked to MS and type 1 diabetes in particular as both autoimmune diseases are more prevalent the further you live away from the equator and the UVB rays that create vitamin D. GMO's are not a listed autoimmune trigger however the hasn't been enough research. One animal study showed Bt toxins produced by GMO corn has been shown to significantly alter immune function in mice and may cause disrupted immune function in the gut.
179856 tn?1333550962 -------------------------------------- Higher HCC risk with increased insulin resistance in hepatitis C patients May 12, 2010 Recent studies have demonstrated that type 2 diabetes mellitus (DM) is associated with high risk of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis C. Insulin resistance (IR), which correlates inversely with circulating adiponectin concentration, is a consistent finding in patients with type 2 DM.
Avatar n tn So I wouldn't rely on anything a GP said about diabetes. If I want information about diabetes (I have type 1, autoimmune diabetes), I ask my ENDOCRINOLOGIST. Not a GP. Questions I might ask my GP include: a) Hey, does this look infected? or b) Can I have a referral? Uh, yeah, that's about it.
Avatar m tn I am also walking everyday but I do work 10 1/2 hour days sitting at my desk and have a 1 to 2 hour commute in the am and pm so I am pretty tired when I get home and my excercising is minimal.
Avatar m tn Older patients and patients with poorly controlled diabetes mellitus have a greater risk of developing infections during HCV treatment. ------------------------------------------------------------------- In this study 319 patients: http://www.ncbi.nlm.nih.gov/pubmed/18458815 During the treatment with pegylated interferons and ribavirin, we did not find a correlation between neutropenia and infections.
1815939 tn?1377995399 Also http://hepatitiscnewdrugs.blogspot.com/2014/11/well-controlled-hepatitis-c-no-dent-on.html?m=1 Laurie Barclay, MD November 12, 2014 Survival in patients with chronic hepatitis C virus (HCV) infection and advanced fibrosis or cirrhosis who achieved sustained virological response (SVR) is similar to that of the general population, according to a retrospective study published in the November 12 issue of JAMA.
686869 tn?1227203535 As I understand you you're taking 4 mg Prograf a day and 1000 mg Cellcept. I am 8 years out and I'm taking 2 mg Prograf in the am and 1 mg in the pm.
3133172 tn?1342659330 If that is the case, (1) how would one know before it's too late? and (2) would this not be taking a huge risk for someone who is cirrhotic? This is troublesome to me. Do I take a risk and treat and maybe go into failure? Or do I not treat and just....... wait for........ end stage anyway but maybe later?
181575 tn?1250202386 Notes from "Chronic Hepatitis B: Preventing, Detecting, and Managing Viral Resistance" by Keeffe, Emmet B., Dieterich, Douglas T., Pawlotsky, Jean-Michael, and Benhamou, Yves in Clinical Gastroenterology and Hepatology 2008;6:268-274. Full paper in http://www.sciencedirect.com/science/journal/15423565 1. Monotherapy using lamivudine has the longest history of use and shows highest rate of resistance.
545538 tn?1295995617 org/personal_pages/user/568322 the bottom line is that even mild insulin resistance (type 2 diebetes), even a fasting glucose that is say 10 or 20 points above normal, can reduce the chances of a cure by 10% or more. Since many with mild IR don't treat for it, this lowers the chances of the group. This is because higher blood sugar means insulin resistance, means more insulin is produced to compensate, and insulin interferes with Interferon. The higher the untreated IR, the lower the cure rate.
Avatar f tn Reduction of new coronary events and new atherothrombotic brain infarction in older persons with diabetes mellitus, prior myocardial infarction, and serum low-density lipoprotein cholesterol >/=125 mg/dl treated with statins. 1 A prospective study in which 529 diabetics, mean age 79+/- 9 years with no morbidities as mentioned above were divided into 2 groups; one treated with statins and the other with no lipid lowering drug.
Avatar n tn The RVR for some other treatment drugs seems better than that of telaprevir (84% of patients in a TMC435 trial stopped treatment after 24 weeks, and almost 100% of geno 1 naive patients apparently did in a PSI-7977 trial) -- would that be a good reason to check out trials using those drugs? 2. Trial drug vs placebo. Most trials are double blind with a placebo component so one couldnt' be assured of getting the treatment drug.