Researchers reported that women in the study fared better than men from either treatment and that Truvada was superior to tenofovir alone in lowering viral load. However, HBeAg seroconversion and HBsAg clearance rates remained low in both groups, according to their report published in the January 2014 issue of the journal Gastroenterology. (1)
Source: http://www.ncbi.nlm.nih.
The iPrEx investigators performed hepatitis B serology tests at study entry and again at the time of Truvada discontinuation. People with positive hepatitis B surface antigen (HBsAg+), or with an isolated hepatitis B core antibody test (anti-HBc+) could enrol if they had no clinical evidence of cirrhosis and their AST and ALT levels, as measured by liver function tests, were less than twice the upper limit of normal and bilirubin levels were at or near normal.
absolutely off label, one might even think about truvada plus immune globulins plus vaccine since truvada has been used after transplant to prevent reinfection and it worked on 100% persons
it would be interesting to see a study on antivirals to prevent hbv after exposure but i guess it would be too difficult to make such a study and especially to find the subjects so transplantation might be the closest to this situation considering transplant recepients have a worst situation because they hav
thats just made to please insurance companies, infact you can t measure effectivness of this potent combo with hbvdna in the blood because it gets to und, to measure difference you need to measure hbvdna in the liver because it never gets to und in the liver
anyway those with very high hbvdna, where etv mono is not potent enough to make hbvdna und, did have a difference and also hbsag serocoversions were higher on combo
that s just a advertisemnt website, look for the poster here in the commun
I'll start 1st by saying I'm a gay male who sought out Truvada as PrEp as a way to further eliminating my risk of HIV. Late October 2015 I sought out an infectious disease Dr who was knowledgeable of Truvada as Prep. Prior to him giving a prescription I was required to have a full blood panel along with a HIV test also screened for Hepatitis. This is when I discovered I was Infected with Chronic HBV. I had elevated alt & ast as well as a viral load in the millions.
Yesterday, I took 1 Truvada at 7am but since I was in a hurry after dinner, I accidentally took one more Truvada last night. I tried to vomit it up but I was able to vomit only a part (dissolved part) of it. Because of panic, I forgot to take Kaletra last night. I rushed to the A&E and asked the doctor's advice on what to do. Since I waited for more than 3 hours before I was able to see the doctor, I was already drowsy when the doctor talked to me.
Since the chances a quite low Can I stop taking pep or can I stop kaletra and remain with truvada take it upto 28days.coz kaletra gives me diarrhea.
How can I change from taking Truvada in the noon to taking Truvada at midnight? For instance, should I do two doses of Truvada in one 24 hour period or should I do no doses in one 24 hour period to get it right?
3. When the doctors prescribed the medication I ended up taking 4x the recommended dose of Aluvia. This was due to me having received four cans of Aluvia,not realizing that each can was meant to last 1 week.
I am a gay male and have taken Truvada as PrEP daily since last November.
This past week, I ran out of my Truvada after taking it on Tuesday morning. Prior to that, I had taken it daily for more than a month. I did not take Truvada on Wednesday or Thursday. I changed insurances and wanted to wait to pick up my refill until I got my copay and assistance straightened out.
On Friday I had anal sex as the bottom with a man I know who says he is negative.
Tenofovir (Viread, also in the Truvada, Atripla, Complera, and Stribild coformulations) is among the most widely used antiretroviral drugs, as it is highly effective and generally regarded as safe and well-tolerated. However, it can cause kidney toxicity in susceptible individuals and is associated with bone loss that begins soon after starting treatment.
I have been taking Truvada since 2008, 5 months ago I did the pregnancy test, the result was positive.
I am worry about side effects to my baby if I continue to take Truvada during my pregnant...
Does anyone have same experience, please tell me more, thx.
So I had a discussion with my doctor yesterday regarding the recent elevation in my AST, ALT ( about 1.5 x ULN). I am LAM resistance, on Truvada for almost 2 years now. Everything else (HBV DNA undetectable, ultrasound ok, CBC, fibroscan + all other stuff i have no idea) came back normal. AST + ALT was in normal range all the time but 3 months recently have been up a bit.
She advised me to continue monitoring my condition and warn me about possible resistance.
After several hours going from a hospital to another, I finally could get a Truvada pill in the very deadline limit of the treatment, probably between the 72nd and 74th hour after the sex.
I was quite desperate and I felt that the staff in this hospital wasn't too much prepared to take cases like mine with HIV risk envolved. It took too many hours, even though I tried to explain them the gravity about this situation.
This is reassuring because it is only one drug in truvada which I started taking at 36 hours (keltra was added at the 60 hour mark) and the study was specifically designed for unprotected vaginal exposure. In fact only one monkey tested positive for SHIV when administered pep at the 72 hour mark post exposure. The monkey did however only test positive 16 weeks post exposure as compared to the 4 weeks the untreated control group started testing positive for the virus.
he started as immune tollerant so similar to your situation but had hdv too that to me is worst anyway even if there are reports that hdv suppresses hbv.
hbv+hdv is way more difficult to treat and cure than hbv only.....
Will truvada and and a respiratory antibiotics have interqction/ side effects if simultaneously on both medicine?
or which antibiotics and safe with truvada for respiratory infection?
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