temodar and thalidomide

The study compared the effectiveness and safety of the combination of thalidomide and topotecan, a chemotherapy often used for ovarian cancer, versus topotecan alone for treatment of recurrent epithelial ovarian cancer in patients who had received prior treatment. Epithelial ovarian cancer is a disease in which cancer cells form in the tissue that covers the ovary.

” The study compared the effectiveness and safety of the combination of thalidomide and topotecan, a chemotherapy often used for ovarian cancer, versus topotecan alone for treatment of recurrent epithelial ovarian cancer in patients who had received prior treatment. Epithelial ovarian cancer is a disease in which cancer cells form in the tissue that covers the ovary.

Now the tumor has recurred a third time and they are trying Temodar again. What other treatment options would you consider at this point?

She had a surgical resection near the end of November and is currently in her third week of Proton Therapy and chemo with Temodar. Her tumor was in the right temporal lobe and the remaining tumor they couldn't remove (about 10 percent they said) is on her right insula. Hoping to chat with other people in the same boat as her. What if any side effects did you incur on Proton therapy? Did everyone who had proton therapy to their brain have to be on a steroid? Did anyone NOT lose hair.

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A month ago my husband (41) had a tumor resection of a GBM in the left temporal/frontal lobe. He is still recovering from surgery and has begun cancer treatment (temodar& radiation) a week ago. He has a previous accident injury where he has struggled with neck pain for ten years. He has been on suboxone for probably 7 years now. He is currently taking his suboxone but is not getting any relief for his head pain.

HI, I AM WITH OLIGODENDROGLIOMA,, NOW ON CHEMOTHERAPY-TEMODAR 350MG.

After having surgery in Oct ' '04 for stage 3C and then having a year and 1/2 remission, I've be battleing a 2.6cm lesion down in the colon area. 2nd time on taxol gave me a 6 month remission. 10 months on doxil brought my ca125 in normal range after 2nd treatment. This past June and July numbers went up again. CAT scan showed same lesion still there. I started topotecan July 28th with a ca125 of 142. After 1st round, 3 infusions, ca124 dropped to 42.

Peripheral neuropathy has been seen in association with the following antibiotics metronidazole, nitrofurantoin, thalidomide and isoniazid. What are your neurological symptoms and has a physician correctly attributed them to sulfa drugs? There is no known peripheral neuropathy with the use of cephalexim, particularly short-term use. You can also check with the pharmacist.

i used pressure bands. you can get them from your pharmacy. they're generally used for those who have car sickness. ask if they carry them if you can't find them. they helped me, but everyone is different. try to take sips of water throughout the day. if you are sick like this every day for a long time you should go talk to your doctor. they do have medicine to help this sort of thing. thought i am wearing of it (ie: thalidomide used in the past was thought safe.

I need to know what is wrong? how do I stop the pain? I had chemo for Limphoma, and I started to get massive body aches, my right hand started to get numb and I was told that after the chemo it would be over. But is not, I finished chemo July of 2009 and I am still in pain, my hand is so bad I have to keep it down, because it gets numb constantly, I told my doctor and she said that it has nothing to do with the chemo. I bearly sleep and I am tired all the time.

It is very difficult to treat, but current therapies include steroids, vitamins, cryosurgery, thalidomide and UVB light. If staphylococcus or other infection is present, then antibiotics may be needed. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor. I sincerely hope that helps.

Hey y’all so I was told I had a UTI and not a std by my doctor and gave me sulfamethoxazole/trimethoprim and I told her that I took azo too, she said it was fine with it. So my question is does azo effect any other body fluid colors besides oranage urine can it change semen?

Hi I also have complex partial seizures which are being controlled w/anti seizure meds. Along w/1000 ml of Keppra I am taking 400 ml of Lamictal. I have a meningioma in the left petrous apex, meckle's cave and clivas... I had gamma knife radiation in 2002 and the tumor went from 2.6 x 2.2 x1.0 cm to 2.0 x 2.0 x .9 presently. The only symptoms I had at the time of diagnosis was left sided facial tingling. I now have epilepsy, trigeminal pain and severe headaches...

Treatment includes steroids, vitamins, cryosurgery, thalidomide and UVB light. In the event that staphylococcus or other infection is present, antibiotics have proven effective. Your father needs to take the antibiotics but for the other treatment options you need to discuss them with his dermatologist. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided.

Apparently its in two places, frontal cortex and thallamus and hence surgery was ruled out. She is on 4th week of radiation [6week plan] and plan to start chemo next week. Now she is experiencing headache and nausea. She is not on steroids. Is this normal? are we missing something? What are we to expect in the near future? Any guidance is appreciated.

Since the diagnosis of Glioblastoma grade 4 in August, my husband has had the tumor removed and completed the round of radiation and chemotherapy - temodar. Recently I have noticed him being very short fused and argumentative. The slightest thing sets him off as if he had been personally attack. I have also noticed depression setting in. I'm assuming this is all part of the treatment and diagnosis.

Hi, Prurigo nodularis is very hard to treat, but current therapies include steroids, vitamins, cryosurgery, thalidomide and UVB light. In the event that staphylococcus or other infection is present, antibiotics have proven effective. A physician may administer a strong dose of prednisone, which will almost immediately stop the itch/scratch cycle. However, cessation of steroids allows relapse to occur, usually within a few weeks.

I have been treated with several meds, including, but not limited to Iodine drops, Thalidomide, Prednisone, and topical steroids. I am now on 10 mg of Prednisone. I have been on that dosage for 6 years now, and the medication is not treating my body very nicely with weakened joints that ache, bad bruising on my arms and legs, weight gain, and a host of other problems that go with the steroid use. One of the best things for the E/N is the application of a topical steroid, Lydex cream.

Hi, i come from the HCV post treatment issue subforum, that board is not really fast with answers and this goes to the people who have done Interferon treatment at least one time and who experience persistent limitations in their cognitive functioning as well as physical symtoms like fatigue , muscle weakness and so on. the key to all these symtoms lies in the brain where Interferon acted because it is a systemic treatment. it affects the whole body, including the brain.

m still able to walk (with a few balance issues here and there). Anyway, I am NOT a doctor, and each person's situation is different, so don't be afraid to get a second or third opinion on your husband's treatment options. If, after consideration, your husband opts for radiotherapy, ask your doctors about doing it concurrent with Temodar (temolozimide). I took that with my last radiotherapy.

One thing I can tell you is beware of certain chemos, like temodar , it can cause lukemia in people with NF, and radiation is also a no go for people with NF. Good luck.

In the following text they use regular mm measurements which is easier to understand. 18mm is around 7/10 of an inch. 20 is .79 and inch and 23mm is just under an inch (an inch is 25mm) about the size of a quarter. I am only a layman, but what I glean from the report is that there is increased blood flow to the area that is enhanced - the area of the tumor - and that is concerning them for being a tumor. Sorry I am not much help. I know your husband has had quite a battle.

Temodar and thalidomide

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