It would depend on what the source of your bilateral ptosis is. If it is a neuromuscular junction abnormality, for example, then the biopsy would not be helpful. However, if it is a myopathic process, the muscle biopsy may be helpful. Are you scheduled for the biopsy?
Thank you for this opportunity to answer your questions, I hope you find the information I have provided useful, good luck.
This drug is an acetylcholinesterase inhibitor, thus it keeps acetylcholine in the neuromuscular junction and as a result neuromuscular transmission inproves and the muscle weakness and diplopia improves briefly. About, 30% of patients with MG also have thymomia (tumor of the thyroid gland) and some studies show that for these patients, once the thyroid gland is removed their MG symptoms are greatly improves.
Electromyography on the other hand is used to diagnose diseases that may be classified into one of the following neuropathies, neuromuscular junction disease and myopathies. This should be normal because the etiology is not related to either of these.
So consult with a neurosurgeon along with your MRI and he will best guide you about the course of treatment. Take care.
Myasthenia gravis is a problem at the neuromuscular junction, the place where the nerve meets the muscles and sends chemicals across to make the muscles contract.
In general, there are several myasthenic syndromes that have similar features, though some may show transient improvement with activity followed by subsequent fatiguing. Negative ACE receptor blocking/binding antibodies do not definitively exclude myasthenia.
s therapeutic effect by blocking neuromuscular junction, which resultis in paralysis of targeted muscle. However, therapeutic effect lasts 3-6 months. The clinician really needs to know whether mechanical blockage of tmj is present or not. Seeing a competent tmj specialist is advised.
When Botox is administered to neuromuscular junction, it makes the muscle stop contraction, the effect lasts about 6 months. However, I do'nt think botox is a good treatment of choice. A well made occlusal appliance can eliminate jaw clenching and masseter muscle relax almost instantly. Seeing a tmj specialist who can deliver an effective occlusal appliance is advised.
They could be trauma or diseases of the brain or spinal cord (CNS), peripheral nerves, neuromuscular junction, or the muscles. CNS trauma and infection are perhaps the most common cause of hypotonia, both in infants and in children. Trauma to the brain may occur prenatally (before birth), perinatally (around the time of birth), or postnatally (after birth).
it is a disease of the motor nerves, the muscles or the neuromuscular junction. Fasciculation were correlated with body weight and height and to the anxiety levels, regular strenuous exercise. Attention deficit disorder or drugs used to treat it and a related disorder may be a contributing factor.
Genetic and environmental factors also contribute.
Hi there. Ocular MG is a disease of the neuromuscular junction resulting in muscle weakness and fatigability. This is an autoimmune disease where anomalous antibodies are produced against the acetylcholine receptors in voluntary muscles. The most common presentation is double vision and eyelid drooping or ptosis wherea the pupil is spared. Diplopia is seen when MG affects a single extraocular muscle in one eye, limiting eye movement and leading to double vision.
What does a few focal regions of increased MR signal at the juxtacortical gray-white junction mean? Can vasculitis secondary to migraine cause this? In addition, what is increased T1 and T2 signal changes identified in multiple levels of the thpracic spine most compatible with hemangiomas involving T12,T9, and the T5 vertebral bodies. Smaller hemangiomas questioned at T8 and T7 versus focal fat. I don't understand this and could really use some knowledge.
There are multiple conditions that can cause eye symptoms, including muscular problems and problems in neuromuscular junction or the nerves that “activate” the eye muscles. The pattern is unusual as you describe these coming every 3-4 days. Based on your information I cannot correlate your symptoms with the neck movement.
Before being able to treat your symptoms, it will be important to find out what the cause is.
If I may, let me comment from the professional side. I think I can speak from a qualified point of view having learned the Neuromuscular techniques. The most important aspect of any treatment is a proper diagnosis. The NM techniques are intended to reduce muscle tension/spasm as a means of reducing pain and finding the correct 'alignment' of the TMJ. It can be effective, but if the dentist uses this technique exclusively I would be cautious.
If I understand you correctly, you do not currently have a diagnosis of ALS but are concerned that these symptoms of the twitches could be an indication of ALS. ALS is a neuromuscular condition, and I agree that your symptoms do seem to be neuromuscular in nature. I don't think you should be worried about ALS necessarily, though. There are many different things that could cause these symptoms. I would recommend going to see a neuromuscular specialist to get testing.
Myasthenia gravis is an autoimmune disease in which the body makes antibodies that attack a recept located at the junction of the nerve and muscle. This causes impaired neural transmission leading to weakness of muscles. There are various forms of myasthenia gravis. These include ocular (affecting eyes predominantly), generalized (affecting the arms/legs/trunk predominantly), or mixed.
I have been having dental pain for 3 months now(not dental related according to 3 dentist) Most of the pain is in the uppermost area of the gums and my cheek is sore.I was checked by my physician who said its not tigeminal neuralgia. I was checked by a ENT who said it may be a Nerve problem(seems like he guessed)because when I left he said"let me know what happens Im always learning too". I seem to think somehow its dental related. Could this be TMJ?
Sorry to hear about what you are going through first of all. Depending on the amount of time you are in this situation, a Neuromuscular Dentist might be able to help you with positioning of your jaw and teeth in a position that you would get the least amount of pressure on your teeth and jaw, and allow your jaw and teeth to settle and heal.
(http://top3dentists.
An autoimmune condition which causes weakness secondary to antibodies formed against acetylcholine receptors in the neuromuscular junction. Muscle weakness is especially common in those muscles controlling eye-movement but may affect skeletal and respiratory muscles as well. Your description of symptoms improving with exercise make this very unlikely since symptoms in MG worsen with exertion.
Perfectly normal.
Basically the heart works like this..
Most folks hearts rely on the atria to keep ticking.. The atria beats at rates above 60 bpm in most cases.
If for any reason the atria stops working.. Or slows down below 40- 60 bpm the Junction takes over. This is a healthy mechanism that has evolved to act as a "fail safe" in case something goes wrong.
When the junction takes over the heart rate will fall to about 40- 60 bpm until the atria is ready to take back over again.
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