t smoke, do exercise, am thin). My doctor put me on a diuretic, Tekturna and Bystolic, and within a week I had completely lost my sense of taste! Anyone else experienced this? I'm wondering if it's a side effect that will wear off if I just stick it out. The combination seems to be working well to lower my bp and hr but I'm losing weight (a bad thing) and really, really miss food!
You'll find a search option at the top of the page. Search "protease inhibitor" and you'll find a lot of information here. Yes, a lot of people here do know about PIs, as we call them occasionally, and there is quite a bit of information already covered. So do a little research first and see if you still have questions.
This is known. Are there any similar action in the protease inhibitor, such as Kaletra (lopinavir) for example?
Have you ever thought about that?
I read - sometimes laugh. Simvastatin, vitamin D, which the Chinese poeben, mythical new drugs, masturbation with measurements of the level of HBsAg, and other nonsense....
Lisinpril can cause a chronic cough and you should stop this medication to see how the cough changes. It may be replaced with valsartan or candesartan which do not usually cause this side effect. The verapamil usually does not cause this side effect. This may not be related to your medications, and chronic cough or ' bronchial asthma' may actually be cardiac in nature ( e.g. CHF). Make sure your physician takes this other consideration into account.
Sorry to hear of your failure to tx, which Protease inhibitor were you on? I have heard of someone having ringing in the ears but I don't remember the situation, maybe they will chime in later. Read around and stay in the loop, something has to be approved soon especially with all the new Polymerase Inhibitor's in clinical trials right now. It really looks like big Pharma is trying hard to create something new and better so that's good and in your favor.
ve been turned down so many times for be a Telaprevir failure. I guess all the protease inhibitor trials are going to definitely be a no go for me.
This whole thing is so unfair! I'm very angry about being kicked to the curb!!! I really don't want to be a whiner, but hey, you know, I think that I've earned the right to whine a little since I've done these awful treatments 10 times with never being given the pleasure, even once, of being told, 'you are undetected'.
Definition: An artificial copy of a nucleoside. When incorporated into a virus DNA or RNA during viral replication, the nucleoside analog acts to prevent production of new virus. Nucleoside analogs may take the place of natural nucleosides, blocking the completion of a viral DNA chain during infection of a new cell by HIV.
A new 3-class DAA combination that includes grazoprevir (NS3/4 protease inhibitor) coformulated with ruzasvir, a novel NS5A inhibitor and uprifosbuvir, a novel NS5B inhibitor is currently being studied, with or without ribavirin, in the C-CREST trials in treatment-naïve and experienced adults with genotype 3 infection.
I perceive that if you are taking an ace inhibitor & then add a diuretic you would have to reduce the ace inhibitor dose to offset the diuretic as the heart would have to beat faster due to the dilation and less fluid. Would this combination cause tachycardia and how should the dose be regulated?
Well, Rocker, I am unhappy to report that I've been given the official, 'NO WAY, JOSE' from Schering on ever being allowed to do the Boceprevir trials, or any other Protease Inhibitor. It's not unexpected, but discouraging none the least. There's really not much out there for me anymore as far as hope for any treatments; unless or until a polymerase inhibitor trial would ever take me.
CHECK THIS OUT....25th November 2008
An ongoing Phase IIa study on Schering-Plough's next generation Hepatitis C protease inhibitor is encouraging.
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