Edema (fluid accumulation in any body part, resulting in swelling) has been reported as an adverse event in 37% of pancreatic cancer patients taking Tarceva, although this side effect has not been reported in lung cancer cases.
However, the type of edema associated with Tarceva use is either generalized or involves a swelling of both legs. Swelling in only one leg may not be due to this drug. Unilateral leg swelling may be due to a local infection (cellulitis) in that area.
Asians, women, non-smokers, and those with adenocarcinoma histology. This drug still has been found to benefit males, smokers, and those with squamous cell histology, but to a lesser extent.
Thanks for your response. To clarify: his treatment was adjunctive. At the time they saw no sign of cancer outside the lung. Now, however, after 4 rounds of chemotherapy the disease seems to have spread during treatment with taxotere and cisplatin: it's now in the liver, bones and adrenal glands. His original tumor was EGFR positive that is why Tarceva came up as a viable second step.
He had more chemo for precaution. After one year, the cancer came back into his Adrenal Gland. It is also in his Lymph Nodes. They put him on Tarceva( a pill he took everyday) And after 6-7 weeks, he had tests done which showed it didn't do anything.. the tumor has grown. They said there is no other options.. no surgery/ no chemo/ no radiation. Has anyone out there had a similar diagnosis and is there any hope for him. I want a second opinion but do not know even where we could go.?
m doing research as quickly as I can to help she and her husband make an informed decision about what to do...if anything. The local drs are recommending 4 weeks of full brain radiation followed by tarceva. Prior to the finding the mets, they were planning 6 weeks of radiation to the right lung in combination with etoposide and cisplatin.
I'd appreciate any feedback. My thanks in advance to all responses....
My father who is now 83 yres old is diagnosed with non small cell cancer with a large 3 inch mass in his upper right side. They state it is somewhere between a stage 2 and 3 due to the size. He is schedules to start radiation treatment in a week. However, they did state he is fit enough to have sugery but there is not guarantee he would not have complications from this. We are struggling to determine what is the better path to take. Will the surgery give him a better chance vs the radiation.
Hi. Which particular "chemosensitivity test" are you referring to? There is no single laboratory procedure which can test for the sensitivity to chemotherapy of all types of tumors. In breast cancer, there's the Estrogen Receptor (ER) and Progesterone Receptor (PR) assays to determine sensitivity to hormonal treatment. There's also the HER-2 (human epidermal growth factor receptor 2) assay for determining sensitivity to Trastuzumab.
Hello I am a caretaker. My client was diagnose with lung cancer stage IV. It has already spread to the spine, both lungs and the lymph system. Doctors triede Tarceva for 3 weeks but her body had a very bad reaction. For the spine they did radiotherapy. But since she was diagnose 3 months ago she has lost aalmost her voice. she is using oxygen for the major part of the day but doctors don't wan't to talk about time. no more medes will be given and she was reffer to hospice....
She has done very well with chemo and radiation until recently. She was started on Tarceva about 3 weeks ago. Recently, she has been experiencing a lot of confusion. I cannot find anywhere that this is a side effect of Tarceva (it is the only drug she is on at this time). Is it possible that she has a brain metastases? If not, what are the likely causes.
In 2005, he had Tarceva. In 2008 they discovered metastasis to the liver (3 lesions) and he underwent chemo again (I think Avastin) and he finished the treatment in March. The doctor said the tumors in both the lungs and liver were smaller.
For the past 3 weeks he´s been vomiting, but sporadically. There is no pattern. It doesn´t matter if he eats lightly or heavily. Some days he vomits once, some days nothing.
He went to see a Gastroenterologist. They did a sonogram...
He started Tarceva this January but it seems it did not work as the cancer spread to brain…. 9 mets were identified in the initial MRI 2 weeks ago but the subsequent MRI right before yesterday’s gamma knife procedure (which removed 7 mets) evidenced numerous other tiny/small tumors spread all over the brain….He has been in relatively good condition (eating well, no weight loss) until these new mets emerged (which affected his walking and reading ability)….
WOW, this is the first time I've ever been on a site and started writing to total strangers. Its kinda cool! I SO appreciate all of the advice! Well, I should come clean with something...last Sept I was diagnosed with stage 4 lung cancer. Inoperable, i was given 6 months to a year to live... with treatment. I've THANKFULLY made it past a year. i guess the LAST thing i should be worried about is my weight, right? The pain i get daily is from my chemo medicine, Tarceva.
Hi,
Your concerns are valid. Lung cancer is afterall, the biggest cause of cancer mortality. For this post, I can only work with the stage information, your doctor likely has better estimates.
Much of the answer here depends on how much the disease is affecting her daily living. If she stays in bed most of her waking hours, then treatment may only make an impact on symptom improvement. If she is able to maintain a fairly active lifestyle – then treatment may help extend survival .
t recieved my period since september 2008, and its now april 2009. i have a large lump right under my nipple and i think i just found another lump under my breast that is small but kinda sore. i was told that i am slightly amnemic, but i've been trying to be as healthy as possible... im just really worried and i want to know whats going on with me.. does anyone have any ideas or advice?
It is common for many young women to have a breast lesion similar to the one you describe. In medical parlance, it is called a fibroadenoma. It is sometimes called a "breast mouse" because of its mobility.
Please dont worry about it.
However, this should be a good opportunity for you to learn about breast health. Please surf the internet to access sites that describe the correct way to perform a breast self examination. Perform this every month.
Lumps that do not hurt when you press down on them, and are in and around the lobules/stroma of the breast are cancer lumps. Breast cancer occurs in the lymph system.
Certain moles also indicate cancer. Melanoma with asymmetrical and uneven flat edges are cancer moles. Melanoma with symmetrical, even edges are noncancerous moles. Here is a link for cancerous moles. (https://www.google.com/search?
She is not a candidate for treatment and is refusing even palliative tx such as Tarceva. PET Scan showed no evidence of cancer in brain, liver or bone. Because she is experiencing no symptoms she is hesistant to participate in a home hospice program. What symptoms are generally experienced and if possible a general timeline for disease progression.
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