Like other forms of breast cancer, triple-negative breast cancer is treated with surgery, radiation therapy,and/or chemotherapy.It's a good thing that there are no lymph nodes involvement,but based on other features of the cancer, such as stage and grade, your doctor/oncologist is the only one to determine the best treatment approach in your particular case.
I was Diganosed with stage 2B Triple negative breast cancer in December 19, 2006.All my tests came back one positive node and the cancer in left breast. I had Chemo then before I finished Chemo the cancer came back to the same 2 areas.Then I had a masectomy followed by more chemo and 7 weeks of radiation. Just recently I asked my Oncologist to order another Pet Scan just to make sure everything was going good. The first Pet scan in August 22, 2007 came back negative.
I would like to add that since Triple Negative Breast Cancer (TNBC) refers to the fact that the cancer cells are negative for estrogen and progesterone receptivity,it is generally considered more aggressive.
What you won’t need is a long term drug treatment. Unfortunately TNBC doesn’t depend on estrogen or progesterone to grow, as most breast cancers do that need Tamoxifen or Arimidex to stop the cancer from growing.
I too have had "triple negative" breast cancer, although no doctor I visited with ever referred to it by name. I only found the term in my reading and talking with a friend who was also diagnosed that way. I am looking forward to hearing from you and seeing other responses to this.
the previous PET-CT ON JULY 2011 WAS NEGATIVE AND CONCLUSION was that no evidence of residual hypermetabolic disease seen in lung.. but the recent CT showed smal new lesion 1,8 *2 cm. in comparison to previous.and his new PET -CT in TURKEY hospital FN shows new FDG(+)SUV max:5) pulmonary nodule in the lower lobe of the lung.
what is the meaning of the SUV MAX 5 ?is this means the new nodule has resisitance to TARCEVA?
Edema (fluid accumulation in any body part, resulting in swelling) has been reported as an adverse event in 37% of pancreatic cancer patients taking Tarceva, although this side effect has not been reported in lung cancer cases.
However, the type of edema associated with Tarceva use is either generalized or involves a swelling of both legs. Swelling in only one leg may not be due to this drug. Unilateral leg swelling may be due to a local infection (cellulitis) in that area.
Triple negative breast cancer is just as treatable and curable as other breast cancers. Triple negative just means two things: 1)your tumor was not fueled by female hormones and 2)you are not a candidate for Herceptin or the anti-hormone treatments such as Tamoxifen, so chemotherapy is your only choice.
I had triple negative breast cancer and had my surgery almost five years ago. I completed my chemotherapy 4 1/2 years ago. I am still cancer-free.
I have a friend who one year ago was diagnosed with triple negative breast cancer...For the last year she did all her treatments..chemo, radiation , had a double masectomy. After all of her treatments were finished her petscan came up free. So she was in pretty good shape for around 3months. We just received bad news that the cancer has now spread to her bones, its in her spine, shoulders and her back..She is being treated again vigorously.
Asians, women, non-smokers, and those with adenocarcinoma histology. This drug still has been found to benefit males, smokers, and those with squamous cell histology, but to a lesser extent.
Now she was detetected with cancer again and has undergone Masectomy in august 2008, the cancer was a recuurent cancer, and the pathologyy report shows T4N2M0 IDC GRADE 3 TRIPLE NEGATIVE breast cancer, i do not understand now what line of treatment should be followed. the Metastases was on all fifteen auxillary lymph nodes with pre-nodal spread.
When the words first-line and second-line are used- this is usually in the setting of known (and usually measurable) disease. So if the liver lesion represents cancer - we are looking at first-line chemotherapy for advanced/metastatic disease. This means that the chemotherapy that would likely be recommended would be conventional cytotoxic chemotherapy with or without avastin.
Drugs like Tarceva do have known benefit in the 2nd-line setting.
With BRCA you have a 40% of ovarian and a 90% of Breast Cancer. The breast cancer is usually triple negative breast cancer. I am not sure if that is because most women develop the breast cancer after you have had all your organs removed and you no longer have much estrogen. If you do not have triple negative breast cancer perhaps it means you do not have the BRCA mutation.
5 1/2 years after lumpectomy removing a .8mm triple negative tumor, followed by chemo and radiation, I found another lump in the same breast in early March. This time it was 1.1 cm and again triple negative, grade 2. Had full mastectomy mid April. Have received confusing advice from doctors about follow-up treatment.
1. Taxol 80 mg x12 carboplat AUC 2
2. Taxofere cytoxan 4 treatments at 3 week intervals
3. Do not have any chemo treatment, just regular checkups.
I have triple negative breast cancer with mets to sternum and both lungs. My doc said 2 years more or less when asked. I have friends who tell me that they here of women surviving well beyond 5 years. Is there anyone out there with Triple negative metastatic disease who has survived beyond 2 years? If so, can you please share your experience. Thank you.
The findings suggested that outcome of two types of breast cancer — those classified as HER2 positive (HER2+) and triple negative — may not depend on size alone.
Researchers found that cancer came back more frequently in HER2+ tumors (7.4 percent of patients relapsed) and triple negative cancers (12.5 percent), compared to HER2 negative/ER/PR+ cancer (1.3 percent).
Hi There...
I have had a upper right lobectomy on Sept 14 2001.Stage 1A BAC lung cancer...no chemo or no radiation..clear margins and no lymph node involvement.. ..it's been a little over five years now. cancer free. PRAISE GOD...and thou I realize that 5 yrs is maybe the magic number for most lung cancer survivor's...is it also meant for BAC Lung Cancer...I have heard not so....
Thank you for any information you can give me....
Your question would probably be best answered by someone in the expert forum. I do know though, that my father was given Xeloda for his lung cancer. The doctor described it as a "smart drug" which attacked cancer cells.
My husband was diagnosed with a Pancoast tumor on his lung. He went thru chemo/ radiation and finally had surgery to remove the tumor. It was successful. He had more chemo for precaution. After one year, the cancer came back into his Adrenal Gland. It is also in his Lymph Nodes. They put him on Tarceva( a pill he took everyday) And after 6-7 weeks, he had tests done which showed it didn't do anything.. the tumor has grown. They said there is no other options..
My brother was diagnosed to have Stage III Breast Cancer..he underwent Modified Radical Mastectomy & his histopath results showed positive ER/PR/Her2Neu...what exactly does triple positive test results mean in lay man's term? ESTROGEN RECEPTOR ASSAY = POSITIVE, STAINING INTENSITY=+2, PERCENT TUMOR CELLS STAINED=+5, PROGESTERONE RECEPTOR ASSAY=POSITIVE, STAINING INTENSITY=+3, PERCENT TUMOR CELLS STAINED=+4, c-erb-B2 (Her-2/neu) =POSITIVE...
Decisions about adjuvant chemotherapy treatment are based on several factors including size of tumor, status of lymph nodes, the appearance of the cancer under the microscope, the presence or absence of hormone receptors for estrogen and/or progesterone, as well as HER2 status, the general health of the patient etc. Triple negative breast cancer means that ER and PR status are negative and that HER 2 neu status is also negative.
If the patient improves with the radiation, or maintains adequate strength or performance status(sufficient strength is usually defined as able to remain up and about at least half of the waking hours), you may wish to discuss other options aside from tarceva - such as the original plan of cisplatin and etoposide. This is because there is a known benefit for these drugs in terms of survival when used as first option among good performance status patients.
Recommended
