Tacrolimus therapeutic range
Common Questions and Answers about Tacrolimus therapeutic range
prograf
i wouldnt lower the tacrolimus dose further
very good they are continuing research, rna interference was discovered years ago by a US company but after this discovery it was bankrapt because other durg makers sueing them, don t remember why i only remember they stopped everythign and even website of this company dissapered
so rnai research continued in israel and other countries outisde US, i am very happy to know that research is being conitued in china/australia where infuence of US drug makers is close to zero, especially china
rnai
The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet.
Lithium is one of those meds that you just have to play with. It's a trial and error type of med. Honestly, even a level of 0.9 is not therapeutic for bi-polar disorder. It should be at least 1.0 if not up to 1.5. And 0.6 is definitely not therapeutic. I was on 1500mg of Lithium once daily, extended release, and I still wasn't at a therapeutic range. Everyone is different. My metabolism just happens to metabolize lithium at a higher rate than it does for others. That might be your issue.
His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys?
Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase? Do you favour such opinions as my father has lowered his tacrolimus dose to keep his kidneys safe?
Sir ,will wait for your kind reply.
Thanks.
My seizures were under control for a couple of years even thought my blood results said I was not within the therapeutic range. I moved out of state and my new doctor wanted to increase my dose's so I would fall with the range. I did not care at the time and
let her raise my dose.
Talking with my new neurologist who is the Newsome chair of epileptology and director of the Epilepsy Program told me that in short the therapeutic range is different for everyone.
s hard to perform my job or other daily tasks when my eyelids are so inflamed. I guess steroids are the only option until they develop something better. Is Tacrolimus a promising nonsteroidal option?
The treatments of this condition are application of topical corticosteroids (betamethasone, clobatesol, flucinolone) which will reduce the inflammatory process. Topical immunomodulators like pimecrolimus and tacrolimus can be used in severe conditions.
I hope it helps. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Hormonal contraceptives such as the pill and the patch may increase the blood level of tacrolimus. Tacrolimus may also reduce the effectiveness of these hormonal contraceptives. For this reason women who could get pregnant should ideally use a non-hormonal method of contraception, eg condoms, to prevent pregnancy while taking this medicine. Seek advice from your doctor or pharmacist.
there are prograf assistance programs that the company offers. If this is not feasible than using other cheaper medications such as verapamil for example for HTN for example will alllow much lower doses of prograf to be used (it delays metabolism of the medication) and thus it comes out cheaper.
After joining the Forum and learning about the importance of FT3, I got mine tested and found that even though my FT4 was very high in the range, my FT3 was very low in the range.
After a med change to a combo T4/T3 med, my dosage has been tweaked until now FT4 is .90 (range is .60 - 1.50) and my FT3 is 3.8 (range is 2.3 - 4.2). I did not take meds until after the blood draw. Testing also showed a low level of Vitamin D, which is quite common with hypothyroidism, so I supplement that.
Your TSH really hardly moved. TSH can change by as much as 70% just depending on the time of day the blood was drawn. It's still above range, and AACE recommended many years ago that TSH range be changed to the much more reasonable 0.3-3.0.
FT3 and FT4 are much more important than TSH, especially once on meds. The target for FT4 is about 50% of range. Yours is at 24%. Target for FT3 is 50+% of range, and yours is 16%. So, you are still hypo.
AS I HAVE SUFFERED BREATHLESSNESS AND WALKING PROBLEMS,I HAVE BEEN TAKEN OFF TACROLIMUS AND PUT ON NEORAL-YET THERE IS NO IMPROVEMENT IN MY CONDITION.IS THERE ANY OTHER ANTI REJECTION DRUG THAT YOU WOULD RECOMMEND (I HAVE HAD A LIVER TRANSPLANT RECENTLY)? IN YOUR EXPERIENCE,CAN MY SITUATION BE IMPROVED?THANKS.
Your Tacrolimus test or which ever immuno suppressant you are on should state if you are in or out of range. Good Luck.
It helps us in identifying whether the drug is in a therapeutic range or not. The decision of dosage adjustments depends on the doctor’s discretion and varies person to person. Do write to us again with more information.
Take care and good luck!
I only take 600mg lithium a day and my levels range from 0.5 to 0.7 which is well within the therapeutic range. Each person takes a different amounts and what is a good dosage for one person could send another person toxic or leave their blood lithium levels too low.
i had a therapeutic abortion one week ago when i was 17 weeks pregnant because the baby has a multiple congenital anomalus.i don't have D&C procedure.i am fine and everything go fine but my breasts secrets milk.i took DOSTINEX which is prolactin inhibitor.i am afraid that the abortion may affect my fertility.i wish to get pregnant again so i don't take any contraceptives.i am waiting the blood to stop to have sex again.my question is...
My 18 year old daughter was almost totally resistant to the repeated rounds of SoluMedrol (5 days each time), so in the last two months, she has been hospitalized twice for PLEX (also called TPE, or Therapeutic Plasma Exchange). Each time, a Shiley catheter was implanted in her right internal jugular vein (neck), and she received 7 every other day Plasma Exchange.
The first round in October, she had spectacular recovery, but that only lasted for 2.5 weeks.
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