spiriva and muscarinic receptors

As per the receptors mentioned, dopamine receptors are of course the standard receptors that antipsychotics work on. Muscarinic receptors are ones that current antipsychotics (and other medications) effect but not purposely. They are the reason that antipsychotics (and other medications that effect these receptors) cause weight gain.

There are treatments that can help, such as anticholinergic agents that target the muscarinic receptors in the bladder, and they reduce the contractility of the muscles in the bladder. There can be a number of causes of this condition, including neurological problems, bladder infections (one of the most common causes), medications, cancer, etc. You should be checked for any of these by your physician.

Somebody also suggested that the chemical stress also affects the PSNS muscarinic receptors causing secretion increase and other symptoms. Tranquilizers work to a certain extent. L.

I've been using Spiriva nearly 10 years and this year my PSA results spiked from less than 1 to above 6. Where did you get your info regarding the statistics on prostate cancer, as I would much like to study it.

my husband has copd he uses adviar spiriva and combivent and it doesnt work what can it be thak you

You are obviously doing the right things, including mouth washing after drug use and you are correct that the Spiriva and Duo-neb do not contain any steroid. Unfortunately, some individuals develop allergy to the ipritropium in the Duo-neb or to Spiriva and the drug simply irritates the membranes of the mouth allowing the thrush to take hold. That you also develop candidiasis under your breasts suggests that you might, for some reason be predisposed to this infectious agent.

I have emphysema. i use advair twice a day and spiriva one a day. The biggest problem for me is that I always seem to havemucus build up in the mornings. My doctor has told me to try mucinex, but that doesn't seem to work all the time. So i try using albuterol in the morning to help loosen up the mucus so that I can breath better.

Although I get good (better) results from the combination than Symbicort alone, since starting the Spiriva, I am experiencing very dry mouth, and nasal passages to the extent that I occasionally experience light bleeding when I blow my nose. My questions are, How serious is this side effect, Should I continue using the Spiriva, Continue the Spiriva but stop the Symbicort, or Drop both and just take Combivent which I currently use as my emergency inhaler?

If you are taking Duoneb there is no point in taking Spiriva because Spiriva is related to the ipratropium that is a consitituant of Duoneb. Also Spiriva is extremely drying which may be why you are feeling so uncomfortable. To be using Duoneb five or six times a day you would have to be close to death. Obviously you aren't, so you can cut back without any problem. I have serious COPD and my use of Duoneb averages 3.5 vials daily. The big question is - how bad is your COPD?

Common COPD inhalers that contain steroids are Advair, Symbicort, Breo and Dulera.

I also experience things seeming to shake and I also have a lot of anxiety (My actual diagnosis is not anxiety, but bipolar. Oddly, I get really depressed on bipolar meds.), so there may or may not be a connection between anxiety and things seeming to shake. I notice that repeating patterns shake more than anything else. Lines also shake. I went to an ophthamologist and neurologist and both said there's nothing wrong with my eyes and my brain.

after checking, this bladder problem is a side effect of Spiriva...I had used Spiriva for over a year and the infections/non-infections got more frequent until I had to go to the urologist...I was on Azo Standard most of the time. I alerted my pulmonologist as to my problem and he took me off the Spiriva. Since being off the Spiriva, my breathing has gotten worse....my Dr said there was no replacement for Spiriva...I'm writing to find out what others might know.

I'll try to be brief. My dr. ordered a pft last week (following three ct scans over 16 months). I had been using Spiriva for three years. My question is how long should I have been off the Spiriva for the test to show accurate results? Shouldn't I have had the test before being given Spiriva? Thanks in advance.

Spiriva is very gritty and irritating. Also it is very drying. I stopped using it. And I got off all inhaled steroids because of the serious problems they caused. Now I use only natural anti-inflammatories and am all the better for it (as well as richer). By the way, my COPD is as bad as yours. I was taking acetylcysteine (Mucomyst) by nebulizer for congestion. This is not always available so I had to make do in some other fashion.

s comment about drops, this article mentions the following regarding the class of drugs including atropine - these are called Anti-Muscarinic drugs and in general they cause pupil dilation and can also paralyze the focusing muscles surrounding the eye's natural lens: "Anti-Muscarinic Therapy: A recent review that included 23 clinical investigations of myopia treatments in children found that anti-muscarinic medications (eye drops) had the largest positive effects for slowing myopia pr

coughing phlegm from lungs for the past six months, have taken antibiotics with no results, did take predrisone together with SPIRIVA 18 mcg and ADVAIR 500/50 for the past month. Still coughing up phlegm and have limited lung capacity. Any suggestions comments.

I take my rescue inhaler only when absolutely needed. I had no meds like Advair and Spiriva last winter. And I only had bronchitis once. Went to my family doctor and got an antibiotic for that. I am not suggesting everyone give up their breathing meds. NOT AT ALL. But, personally for me, I am doing better without all those meds. Sure I have symptoms. Some days I do good. Other days not so good. But, at least I am not getting sick nearly as much, while I was being given Advair and Spiriva.

I read that roflumilast is a new drug that controls the inflammation that causes copd to get more severe. I currently use Spiriva and this article said that there was a higher rate of sudden death with the mist inhalers in people with vascular disease. So I am thinking about switching up after talking it over with my doctor.roflumilast is a pill you take daily.So I guess your answer would be anti-inflammatory.

DETROL LA should be taken once daily with liquids and swallowed whole. The dose may be lowered to 2 mg daily based on individual response and tolerability. Refer: http://www.rxlist.com/cgi/generic/tolter_ids.

I have heard "not" I was diagnosed with acid reflux and yet I also have asthma, so they put me on spiriva and activar (something like that) and it didn't bother my so called acid reflux. It's just suppose to help with breathing. It can however bring on thrush, so be sure to wash the inhaler each time after use.

It can be used occasionally, for transient worsening of COPD with Advair, and more regularly with Spiriva. If you find that you have a need for Proventil more than once a day, you should report that to your doctor who may then opt to increase your long acting medication.

Can someone explain to me in medical terms the danger/affect there in mixing a muscarinic M3 receptor antagonist that inhibits acetylcholine-induced contraction of smooth muscle, i.e. respiratory, digestive and urinary tract(s). I recently relapsed after 2 years sobriety after having the PROMETA treatment, a neurotransmitter reversal of sorts and have a good grasp of medical terms.

This was last February. I survived 23 days of utter hell and felt free and clear after about a month. I beat it, I thought. Life was beautiful again! lol I truly felt great. About two months later, my soccer team won a big tournament and I wanted to celebrate so I found one of my old stases and BAM I was once again a full-blown (instead of a recovering) addict. I didn't think I could survive another 23-day hell sentence so I made my second biggest mistake and tried Suboxone.

My guess would be if it is day 5 without the inhalers, then they should be out of your system. I too had problems with Advair and Spiriva. I was diagnosed in Oct. 07 with moderate COPD. Was put on Advair, Spiriva and ProAir as my rescue inhaler. After being on the Advair and Spiriva for several months, I began to become ill. Spent the sickest winter of my life, while on these inhalers. Bronchitis, pneumonia and pleurisy that was so painful for 3 months. I was doing okay before the inhalers.

I currently take advair and Spiriva medication.. is this the one and only mediacation,since there are no genericand here in the united states unlike the rest of the world which has a free market, we are controlled by the drug industry.

At my six-monthly checkup at my local hospital here in Spain there was a replacement doctor and since he was young I thought he might be willing to hear why I was not taking spiriva and steroids. He confirmed that a person with severe COPD MUST use these medicines. But - I objected - they do not cure, they’re only supposed to make you feel a little better and have nasty adverse effects.

Thanks for the input. My MD put me on Spiriva, and during the summer I experienced what felt like about 2/3 lung capacity. Symptoms improved when I went to the coast to get some "clean" air. When I got back to the valley I had a lung function test conducted, and the MD said Spiriva was not medically indicated. So now I'm not sure if I actually have COPD or not. Will take your advice and get a second opinion.

Spiriva and muscarinic receptors

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