simvastatin with grapefruit

thanks Research about the interaction of grapefruit juice with drugs suggests that compounds in grapefruit juice, called furanocoumarins (for example, bergamottin), may be responsible for the effects of grapefruit juice. Researchers believe that furanocoumarins block the enzymes in the intestines that normally break down many drugs. One glass of grapefruit juice could elicit the maximum blocking effect, and the effect may persist for longer than 24 hours.

the most common side effects of simvastatin are headache, abdominal pain/cramps, constipation, URTI, flatulence, diarrhea, asthenia, nausea and vomiting, dyspepsia, myalgia, rash/pruritus(itching). make sure you do not take with grapefruit juice, report any signs and symptoms of infections, unexplained muscle pain, tenderness/weekness. i hope this helps!!! this all i know about the med.

I started taking Valium recently and noticed that the bottle warned not to consume grapefruit of the juice at all while taking this medication. This was a issue for me because I drink hansen's natural cane sugar soda with real grapefruit extract and I had to give that up, but I really didn't want to so I read up on what it will do. One article I came across said it would increase the potency of certain meds by 400% http://www.mayoclinic.

A Potential for Adverse Events Many patients may take their medications with a glass of juice. However, since the accidental discovery of an interaction between the calcium channel blocker, felodipine, with grapefruit juice,1 it has now become evident that grapefruit juice has the potential to alter the plasma concentrations of many medications when they are taken by mouth. In some cases, this may result in undesirable clinical effects of medications.

One thought, did you take anything that may have had a poor interaction with your simvistatin? Grapefruit for example is something that needs to be avoided while taking statins. Grapefruit contains the compound bergamottin, which interacts with certain enzyme systems in the body, such as cytochrome P-450 and P-glycoprotein. These enzyme systems are responsible for breaking down statins, as well as other drugs, into more usable chemicals and transporting them in the body.

Today I got my Cholesterol readings from my doctors office. I was put on Simvastatin 20mg daily, back in September. In October my readings were Total Cholesterol 106 LDL 53 Hdl 29 Triglycerides 121 VDL 24 Then yesterday after taking the Simvstatin for seven months the results were: Total Cholesterol 110 LDL 65 HDL 24 Triglycerides 105 VDL 21 so my triglycerides went down and the VDL went down. However my Total, LDL went up, and my HDL went down.

I wanted to add that I was on the grapefruit diet when I was first put on Oxycontin and my doctor and pharmacist said NO! You can NOT take this medication with the grapefruit juice at all. Do not even drink it at all when taking this medication.

t lift them and they were cramping all the time. My doctor prescribed simvastatin. I told her what happened with the first statins I had taken and she said that this drug would work differently then them. She was right; this one almost crippled me! I got leg cramps so bad I thought they would never go away. I couldn't hardly walk the pain was so great in my legs. Forget sleeping... my legs cramped in places that I didn't know could cramp!

I had problems with aches and pains with Lipitor and switched. It reduced the amount of aches and pains, however try to add COQ10 with your meds. I have found that it helps a lot.

My mother is 70 years old. In the past year there have been many significant changes in her health for the worst. I've gone through 2 family doctors and 2 neurologists and none can explain what is wrong with her. First I'd like to tell you what medication she is currently taking then I'll tell you what's wrong with her. A) Verapamil 240 mg B) clonozepam 1 mg C) simvastatin 20 mg D) levothiroxin 50 mcg E) Benicar 40 mg F) ramapril 10 mg.

, doctor, pharmacist, or dietitian) to eat grapefruit or drink grapefruit juice you should discuss with your doctor the effects of grapefruit on the blood levels of this medicine. These effects can occur even if grapefruit is not consumed at the same time as the simprevir dose. This interaction may occur at any time in your treatment with simeprevir if grapefruit or grapefruit juice is consumed.

Zoloft is one of the drugs that can cause big danger to the liver if used with grapefruit. There are others too but this one is especially common to people on interferon/riba. I sure don't want anyone to make this mistake. There are anti depressants that are safe with grapefruit-Celexa is one of them. I called a pharmacist to confirm this and they said it was a big no-no and quite dangerous even if you don't have liver problems.

Hey Jean. I just joined myself but have been HCV for (by my estimate 21 years now). I won't say it can't be incredibly hard. There's the social stigma, coming to terms with the fact you have it and then the telling of family and friends, not to mention dating and that's just the emotional side. A good place to start is educating yourself about transmission, that way you can feel confident in yourself that you can protect those you love and encounter.

There is only one interaction that would be of any concern. Treatment with both simvastatin and niacin may result in muscle pain or tenderness or muscle weakness. Using simvastatin together with niacin is usually not recommended, but may be required in some cases. If you are using both medicines together, your doctor may change the dose or how often you use one or both of the medicines. It is important to tell your doctor and pharmacist about all other medicines that you are using.

Welcome and thanks for your question. Both are statins that work by a similar process with Simvastatin being considered a stronger med. Below is a quote about a recent study; "There was a study done with 550 people in 1993, that looked at the differences in treatment with simvastatin versus pravastatin. Patients were put on a cholesterol-lowering diet and given one of the medications.

curious if stef2011 or studyforhope or StephenCastlecrag know whether simvastatin by itself can reduce viral load? I've read about the effects in conjunction with NUCS but I'm curious if sim is effective alone.

Here is what I found for Incivek or Victrelis in combo with Pegasys, Ribavirin and Simvastatin. Both PIs are contraindicated.

I have been taking simvastatin for three weeks since having a Tia but have also had a flu like cold for ten days , I am still having aching flu like pains which I would have thought would have passed by now . I don't know if this is a side effect of the drug I'm taking 40mg a day but feel really achy will this pass .

I m at present on Erythromycin for sore throat and as it interact with simvastatin the dr has asked to stop taking it until I complete the course of antibiotic.

I have been taking Simvastatin 20mg for about 2 years, but recently my bad cholesterol has gotten very high to where it is elevated. Now, I admit to not being consistent lately with taking my medication; could this be the cause for my cholesterol to skyrocket?

One group took the antihistamine with grapefruit juice; another with water laced with naringin, the substance that makes grapefruit juice taste bitter; and the third group took the antihistamine with just water. Analysis revealed that the grapefruit juice hindered absorption by as much as half over the group taking the medication with water alone. The difference is said to be enough to generate a critical difference in the treatment of many serious medical problems.

Zosta -10) also has the same effect as Storvas 10 mg. I have had cholecystectomy about 5 years back.

Her alphafetoprotein level normalized within 5 months and remained normalized with maintenance dosages of simvastatin. Repeated imaging studies of her liver never showed any liver tumor mass. [0024] Case No. 3 [0025] A 46 year-old woman with a known Hepatitis C for the last 20 years was found to have an elevated alphafetoprotein level on a routine follow-up.

Simvastatin with grapefruit

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