Simvastatin and side effects
Common Questions and Answers about Simvastatin and side effects
vytorin
In one huge survey, atorvastatin came out on top with the least side effects. Here is some info regarding your question which I found on the internet.....
Atorvastatin 10mg reduced LDL by 30-40% = equivalent to 20mg Simvastatin
Atorvastatin 40mg reduced LDL by 46-50% = equivalent to 80mg Simvastatin
Starting doses for each of the two statins are ....
the most common side effects of simvastatin are headache, abdominal pain/cramps, constipation, URTI, flatulence, diarrhea, asthenia, nausea and vomiting, dyspepsia, myalgia, rash/pruritus(itching). make sure you do not take with grapefruit juice, report any signs and symptoms of infections, unexplained muscle pain, tenderness/weekness. i hope this helps!!! this all i know about the med.
Actually, Lipitor is much stronger than Simvastatin and has a much higher incidence of side effects, unless I have missed some new data. According to the links I have Simvastatin is the safest statin on the market.
I take Simvastatin with no side effects, and have for several years, and so does my husband, also no problems. It's done an excellent job of lowering both our cholesterols.
I am 55 yrs old female and went for a physical and was told i had high blood presure, that day it was 144/92. I had a blood test and it showed high cholesteral 257. Doctor put me on 10 MG Lisinopril. I took the tab for 5 days on the fifth day my heart was pounding so hard in my chest and i felt like someone was sitting on my chest. This happened a few more time over the next week and it would go away after a few min.
The study found that the patients on simvastatin achieved the target LDL level of less than 130, more than those on pravastatin (65 percent on simvastatin versus 35 percent on pravastatin). The most common side effects of the statins in general are nausea, gas, and upset stomach. Less common are headache, dizziness, rash, sleep disturbances, muscle pain, cramps, or weakness.
Hi,
Simvastatin is generally well-tolerated and side effects are rare. Minor side effects include constipation, diarrhea, fatigue, gas, heartburn, and headache. Major side effects include abdominal pain or cramps, blurred vision, dizziness, easy bruising or bleeding, itching, muscle pain or cramps, rash, and yellowing of the skin or eyes.
ref:http://www.medicinenet.com/simvastatin/article.htm
This could be an allergic reaction to the drug. It will stop if the drug is withdrawn.
) For the past 20 years, I have avoided NSAIDs, acetaminophens, other pain relievers and muscle relaxants because of their adverse effects to liver and kidneys (personally more significant because my dad had kidney disease). Since cannabidiol inhibits the liver's production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects.
Vytorin does a remarkable job of reducing your Cholesterol, much better than Zocor (Simvastatin) alone. However, Zetia doesn't seem to add anything to the picture as far as preventing heart disease is concened. But read this about Zocor:
-"Zocor Users Not Warned of Risks:
The FDA's June 2011 safety alert is the most serious of many warnings regarding Zocor and associated risks of myopathy and rhabdomyolysis. Zocor manufacturer Merck & Co.
Though rare, medhelp talked about these side effecs: "The experts at Drugs.com state that while rare, severe side effects may accompany the use of simvastatin. If you experience any of the following, you need to seek immediate medical attention. These side effects include ... rapid heartbeat, irregular heartbeat ... These side effects most frequently occur when simvastatin is coupled with niacin, another cholesterol-lowering drug.
Read more: http://www.livestrong.
I would recommend asking your Dr or pharmacist if these are possible side effects. There could be another reason why you're gaining weight and your BP is up. You should'nt have any side effects from stopping this med but, your Dr put you on it for a reason. I take it you had high cholesterol numbers? See your Dr before you quit taking it. That's just my suggestion.
The main study for Simvastatin was the 4S trial which proved that the incidence rate for side effects at 40 mg of Simvastatin was 1 in 2,220 prescriptions. What is interesting is that the incidence rate in the placebo group was 1 in 2,223. Also muscle pain is a very common complaint and is a symptom of many conditions.
Ed is correct about the half life, a normal 40 mg dose is out of your system within a day. Also, any side effects are usually gone in a couple days or a week at most.
Diet and exercise can be very benificial in many ways for you although I suggest you consult your physcian before begining any cardio vascular exercise and also discuss the side effects of discontinuing any and all medications. Certain medications can become harmful if not discontinued properly.
I think you have a good plan though, I hope you will keep me "posted" ha ha about how you are doing and the progress you are making.
“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen.
http://www.idse.net//ViewArticle.aspx?
The risk of any side effect is anywhere between 2% and 5% which classifies this as very safe. Common side effects are muscle pain and sore joints. I would take it and just keep an eye out for anything that may be a side effect. This link will tell you what to look for;
http://www.emedicinehealth.com/drug-simvastatin/article_em.
I have not taken simavastatin for 4 days and I am still suffering panic attacks mainly morning and the evening. I read somewhere it takes 10 days to get out of the liver.
hey Jeff.. That is a could subject you have brought up.
It will be nice to find a pharmacy that sells good quality meds.. I know in the US it is impossible to test the medication from a third party. Other countries you can..
I have heard of people buying Chinese Baraclude for dirt cheap, and other drugs.. But I am very concerned not be sold something that can poison me. That is the only thing why I did not try Alinia.. It is a very good effective drug against HepB..
was on lipitor for 5 months and switched two weeks ago to simvastatin in hopes of less side effects. just got some blood work done and the liver enzymes are elevated about one and a half times normal. does anyone know if its normal to see a spike in liver enzymes after switching statins or does this mean my body is rejecting the new statin?
She is finding that her hair (which has always been very thick and healthy) is thinning dramatically. She is also taking Simvastatin and an anti-depressant, Citalopram, and an amphetamine for ADHD. Is hair loss a normal side effect of these meds, and, if so, what can be done to combat the problem?
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