Rebif new formulation fda
Common Questions and Answers about Rebif new formulation fda
rebif
A while after it was reformulated, the FDA stopped production and shipments for several months, many people switched to other brands at that time and never went back. I used the new formulation for several months before it became unavailable nation wide.
It is believed that the new formula which uses micro crystalline cellulose as a filler (Nature Throid changed to that as well), makes the hormone not absorb as well.
Hi I noticed a lot of comments on the "New" formulation of the Armour Thyroid tablets. I never got pills from my pharmacy with the "A" I swear all of mine were blank with no logo. I noticed this last batch has the "A" logo, is whiter and does not split in half well at all. Were there Armour tablets with no logo before? I am so confused and upset by this whole problem with this medication. I feel like buying a pig farm and learning how to make the stuff myself.
The answer is no, however the differences are probably not clinically significant. Valium is a brand name. Not a generic name. The generic name is diazapam. The FDA will usually provide a history of changes, although some may be proprietary. You ask an interesting question. Many "common" drugs have actually changed in formulation several times. Synthroid, for example, has changed it's formulation several times since introduction.
Tenofovir alafenamide (TAF), a new formulation that reaches higher levels in cells but allows for lower dosing, was as effective as the current tenofovir disoproxil fumarate (TDF) formulation but had less impact on markers of kidney function and bone turnover, researchers reported at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) this week in Denver.
We have evaluated the potential of a novel vaccine formulation comprising particulate hepatitis B surface (HBsAg) and core antigen (HBcAg), and the saponin-based ISCOMATRIX™ adjuvant for its ability to stimulate T and B cell responses in C57BL/6 mice and its ability to break tolerance in syngeneic HBV transgenic (HBVtg) mice.
May not be available for along time,who knows??? We were not doing well on the new formulation of Armour( weird HYPO symptoms and blood work off after our last refill) anyway and had already switched to Naturethroid 5 weeks ago. However, they are having supply/demand issues and it is also hard to find. They will have supplies filled in aprox. 90 days. You can have compounded dessicated in your MG to hold you over until then. Naturethroid is working great here. You should try it when you can.
I have heard a lot of people complain about the new formulation of Oxycontin .It is called OP I think .Purdue made this new formulation to stop people from abusing it but I have heard a lot of CP patients complain that it doesn't work as good as the old formulation .There is a substance that turns to a gel to keep people from snorting it or shooting it up and that may be what is causing it to not dissolve correctly .That's my best guess about it though .I would talk to my Dr about this .
I saw my neurologist and he said that becuase I had recently had an increase in dosage of rebif it could be making me feel unwell. My symptoms were painful spacticity and urinary difficult (which were all new to me) and I'd swear I was having a relpase. I felt sicker than ever before with MS.
As you may know, I was diagnosed with MS in April and have been on Rebif. I have had 2 relapses while on it. The first one was just a week of muscle spasms. I am currently in the 2nd one now and it has been active since 8/11/10. I have 3 days of I.V Solumedrol the 1st of sept and have felt no relief.
With this one I have been having some new things going on that do not seem to fit with MS, at least not anything I can find. So this is what I'm hoping you can help me with.
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