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Raltegravir trial

Common Questions and Answers about Raltegravir trial

isentress

Avatar f tn At day 22, i took raltegravir from the box but im not sure whether i drank the pill with the water or not. Normally, I remember the pills that I drank through glass of water but i cannot remember this time whether i drank this pill with glass of water or not but i counted pills and i concluded that their numbers are as expected. I searched couple of papers and i concluded not to double the dose in the case of i used that pill.
Avatar f tn combining emtricitabine and tenofovir from the NRTI class, and raltegravir, from the integrase inhibitor class. There ARE alternative drugs available and possibly in Thailand they use lamivudine in place of raltegravir. I am definitely NOT a chemist, so I can't tell you for sure if the combination you're taking is appropriate. You should discuss your concerns with the doctor who prescribed PEP or a pharmacist/chemist. I wish you the best.
Avatar n tn I started PEP 2 hrs later (truvada, norvir, raltegravir, and preszita), my initial results are negative. I do not know the viral load of the patient yet, i can only pray that it is low. I know odds are 0.3% but that doesnt settle my fears, i am young and want to live a happy healthy life with KIDS! DR. please tell me if you have honstly heard of any cases like mine that have converted. I am in awe and feel like my life is totally over and ruined.
Avatar n tn I am currently taking truvada and isentress (raltegravir) is this enough I couldn't get my prescription for dolutegravir filled...is this pep enough?
Avatar n tn m confused on the prescriptions given to me I have a 7 day dose of raltegravir and dolutegravir...thought it was supposed to be 28 days?
Avatar n tn I appreciate your blunt response. I was prescribed Truvada + raltegravir (PEP) but could not obtain raltegravir in Europe. To be fair, I called the US PEP hotline who told me that I could take Truvada as PEP as there are no studies that prove it’s ineffective, so I didn’t start it without advice from the US HIV experts. I agree my anxiety is an issue but I legitimately was seeking an answer.
Avatar f tn Anyways I rushed to the hospital and was put on PEP at a maximum of 3 hours post exposure (truvada and raltegravir). I have taken the pills without missing any doses. At 3 weeks post exposure the lymph nodes in my neck swelled up slightly and I felt a tiny bit feverish. Checking my temperature rectally though revealed it was always in the 37s. These strange symptoms lasted only 2 days...could this be ARS?
Avatar m tn The trial and data for the 12 weeks of Harvoni treatment with the addition of ribavirin was NOT done with the participation of coinfected folks. So there is no current published data, that I am aware of, cpncerning the use of 12 weeks of Harvoni treatment with the addition of Ribavirin for coinfected folks. Only a hepatologist familiar with the latest thoughts on this matter within the hepatology community would know if 12 weeks may also work for the coinfected population.
Avatar m tn I actually went to the clinic, got PEP (truvada 200mg and Raltegravir 400mg), also done hiv prick test which was negative. Dr was helpful and explained everything for me. He also said best thing is as u guys suggest, ask him test but also if he is clear 6 weeks back also, but that also depends on trust. On my side i don't wanna embarrass him as twice he told me not to worry.
Avatar n tn In the following day, I finally could find a very good hospital with a specialized area for HIV treatment, and the doctor was quite surprised that they had given me just a Truvada. She added a Isentress (raltegravir) to my Pep treatment. But I could realized that she was quite worried because I had had only Truvada in the begining of my treatment and in the very deadline edge.
Avatar f tn I am taking Truvada and Raltegravir. Yesterday, (3 days after exposure and 2 days on PEP) I had protected sex with a female partner (I, the insertive male) and when I ejaculated I am afraid some spilled off the base of the condom. If I began PEP 24 hours after possible exposure and had protected sex with someone else on Day 2 of PEP, could I have biologically put them at risk for HIV if by any chance the ejaculate spilled off the condom?
Avatar n tn I started PEP (Truvada and ISENTRESS which is Raltegravir Potassium Tablets) in 47 hours. I also saw some case about PEP with blood transfusion. A 12 years old girl had a blood transfusion with hiv blood, she took PEP( tenofovir, emtricitabine, ritonavir-boosted darunavir (subsequently changed to lopinavir) and raltegravir) after 24 hours and had these PEP for three months. This girl also has cssr5 dna which is a dna that hard to infect hiv.
Avatar f tn Someone in my support group here is in a trial with Kaiser and taking SOC plus the Plough Shearing SI that has a number instead of a name. She's doing very well and will be done in 3 weeks.
Avatar f tn boc trial is working good for me. I went in with a viral load of 13 million, in 2 weeks i had a viral load of 2 million. 1a . there are others here who have just about cleared. they will chime in.i will let you know next tuesday about results for 6 weeks. thats with n2 weeks of boc added.
408795 tn?1324935675 No question here, hell how could I top jackie mason and his HepC transmission by tire story? I started my Boceprevir trial today, got 3 Riba and my first shot. No sx's so far, but you never know, it was just around 3:00 or 2 hours ago. Maybe it will be a smile now, cry later reaction. lol Anyways, I just wanted to let all my friends know that I took the plunge, I better get to drinking some water, just to be safe.
980756 tn?1313445908 well just got my results back for screening to get into trial...passed every hurdle except viral load count...had to be 50000 plus to get in...was only at 21000 grrrrrrrr...when diagnosed last july it was 1600,,,november 3700...
980756 tn?1313445908 Hello all..i hope everyone is doing ok! My nurse called me today about a trial to screen for...Danoprevir with ritonavir..has a 50k viral load minmum to get in..been 6 months since last screening which i failed getting in due to only VL only being 7 k...actually its been 7 k the last three screenings arrrg...missed the BOC trial by 3 k ugh..maybe the monsters have been partying since then...question is do i go for it or do i wait for Teleprevir?
980756 tn?1313445908 well another trial chance bites the dust...screened for the danoprevir trial and my VL came back at 2 k ...this is crazy ...beginning to think that a trial will never happen for me...this was the 3rd trial ive screened for...1st time VL was 7k, 2nd time 2 k, this time 2 k...have had this monster 25 yrs...guess ill wait for Tel or Boc...
Avatar f tn Its been a couple years since I have been here. I did a trial in 2013 with someone that was dosing based on tsh and I eventually gave up. Now looking back I have discovered that I probably was not absorbing the medication. I also know that supplementing with iodine likely sabotaged any progress I was making since is causes tsh to rise in addition to tanking my iron. These are my observations based on the last two years of monthly labwork.
Avatar n tn I started PEP 2 hrs later (truvada, norvir, raltegravir, and preszita), my initial results are negative. I do not know the viral load of the patient yet, i can only pray that it is low. I know odds are 0.3% but that doesnt settle my fears, i am young and want to live a happy healthy life with KIDS! DR. please tell me if you have honstly heard of any cases like mine that have converted. I am in awe and feel like my life is totally over and ruined.
Avatar f tn //www.fda.gov/ForConsumers/ByAudience/ForPatientAdvocates/ucm309863.htm ___________________________ Here is another: The Effect of Telaprevir on the Pharmacokinetics of Buprenorphine in Volunteers on Stable Buprenorphine/Naloxone Maintenance Therapy Co-administration of telaprevir did not increase withdrawal symptom frequency and there were no serious adverse events reported during or after completion of telaprevir co-administration.
Avatar f tn I presume you had anal sex, because oral is not a risk. HIV is only diagnosed from a test so all your details and questions have no answers. Since you have passed 28 days, you can just take a 4th gen test for a conclusive result and all the details you mention which are just question marks will become irrelevant.
Avatar f tn However, after 2013, three-drug regimen consisting of a nucleoside reverse-transcriptase inhibitor (NTRI), (tenofovir plus emtricitabine), along with a third drug, either an integrase strand transfer inhibitor, raltegravir or a boosted protease inhibitor, darunavir/ritonavir is recommended for PEP. Ideally, NTRI is an important component of the regimen because if HIV infects a cell, it first attaches to and fuses with the host cell.
Avatar m tn Most trial exclude post-transplant patients. The only trial that would be conducted would be through transplant centers Have you spoken to your transplant center? They would know about any clinical trials that they will be conducting that you would qualify for. You will need to be under the care of a transplant center if you should make any changes to the drugs you are taking.
Avatar m tn You can get the trial number from the informed consent and maybe send out a message to see who is in the same trial. I was in a trial with IFN, RBV, GS9451 and GS5885. Had to drop after 12 weeks due to viral load going back up as a result of resistance. This was my second attempt at tx - was a non responder the first time. Good luck and hope that you get UND and SVR.
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