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Raltegravir hepatotoxicity

Common Questions and Answers about Raltegravir hepatotoxicity

isentress

Avatar f tn At day 22, i took raltegravir from the box but im not sure whether i drank the pill with the water or not. Normally, I remember the pills that I drank through glass of water but i cannot remember this time whether i drank this pill with glass of water or not but i counted pills and i concluded that their numbers are as expected. I searched couple of papers and i concluded not to double the dose in the case of i used that pill.
Avatar f tn combining emtricitabine and tenofovir from the NRTI class, and raltegravir, from the integrase inhibitor class. There ARE alternative drugs available and possibly in Thailand they use lamivudine in place of raltegravir. I am definitely NOT a chemist, so I can't tell you for sure if the combination you're taking is appropriate. You should discuss your concerns with the doctor who prescribed PEP or a pharmacist/chemist. I wish you the best.
Avatar n tn I started PEP 2 hrs later (truvada, norvir, raltegravir, and preszita), my initial results are negative. I do not know the viral load of the patient yet, i can only pray that it is low. I know odds are 0.3% but that doesnt settle my fears, i am young and want to live a happy healthy life with KIDS! DR. please tell me if you have honstly heard of any cases like mine that have converted. I am in awe and feel like my life is totally over and ruined.
Avatar n tn I am currently taking truvada and isentress (raltegravir) is this enough I couldn't get my prescription for dolutegravir filled...is this pep enough?
1084115 tn?1385228589 Tuberculosis was more common in alcoholic and Child class C cirrhosis (Table 1). Antituberculosis therapy (ATT) is associated with hepatotoxicity in 10%. Hepatotoxicity requires withdrawal, modification, and sequential reintroduction to achieve cure of tuberculosis. Using such hepatotoxic drugs in presence of cirrhosis or advanced liver disease is a challenge.
179856 tn?1333547362 Although clinically significant liver injury is extremely rare from statins, mild increases in liver enzymes can occur in 1%–3% of patients. Because of the concern of possible hepatotoxicity, statins are labeled as contraindicated in patients with liver disease. Given the prevalence of liver diseases in the population, such as nonalcoholic fatty liver disease (NAFLD), hepatitis C (HCV), and others, many patients have not benefitted from the cardiovascular protective effects of statins.
Avatar n tn m confused on the prescriptions given to me I have a 7 day dose of raltegravir and dolutegravir...thought it was supposed to be 28 days?
Avatar n tn I appreciate your blunt response. I was prescribed Truvada + raltegravir (PEP) but could not obtain raltegravir in Europe. To be fair, I called the US PEP hotline who told me that I could take Truvada as PEP as there are no studies that prove it’s ineffective, so I didn’t start it without advice from the US HIV experts. I agree my anxiety is an issue but I legitimately was seeking an answer.
Avatar f tn Anyways I rushed to the hospital and was put on PEP at a maximum of 3 hours post exposure (truvada and raltegravir). I have taken the pills without missing any doses. At 3 weeks post exposure the lymph nodes in my neck swelled up slightly and I felt a tiny bit feverish. Checking my temperature rectally though revealed it was always in the 37s. These strange symptoms lasted only 2 days...could this be ARS?
800851 tn?1260343102 i believe there is some data showing that naturally it can some hepatotoxicity
Avatar m tn In adults and adolescents, hepatotoxicity may occur following ingestion of greater than 7.5 to 10 g (ie, 24 regular-strength or 15 extra-strength caplets or tablets) over a period of 8 hours or less. So, the pain may not be related to your medications. Hope this helped and do keep us posted.
Avatar m tn I actually went to the clinic, got PEP (truvada 200mg and Raltegravir 400mg), also done hiv prick test which was negative. Dr was helpful and explained everything for me. He also said best thing is as u guys suggest, ask him test but also if he is clear 6 weeks back also, but that also depends on trust. On my side i don't wanna embarrass him as twice he told me not to worry.
Avatar n tn In the following day, I finally could find a very good hospital with a specialized area for HIV treatment, and the doctor was quite surprised that they had given me just a Truvada. She added a Isentress (raltegravir) to my Pep treatment. But I could realized that she was quite worried because I had had only Truvada in the begining of my treatment and in the very deadline edge.
Avatar f tn I am taking Truvada and Raltegravir. Yesterday, (3 days after exposure and 2 days on PEP) I had protected sex with a female partner (I, the insertive male) and when I ejaculated I am afraid some spilled off the base of the condom. If I began PEP 24 hours after possible exposure and had protected sex with someone else on Day 2 of PEP, could I have biologically put them at risk for HIV if by any chance the ejaculate spilled off the condom?
Avatar m tn Viagra has some side effects, including hepatotoxicity, acute liver injury. It seems not useful for liver, damaged by HCV. See http://livertox.nih.gov/Sildenafil.
Avatar m tn Alcohol consumption has been associated a higher risk of developing isoniazid-induced hepatotoxicity. Isoniazid should be eliminated from your body about 20-24 hours after your last dose.
Avatar m tn As for the two doses, studies indicate that 28 days is required to give the maximum benefit. Side effects I would suspect will be minimal. Truvada carries a risk of hepatotoxicity but this is not a concern after two doses. Your risk is fairly low so take a 4th Gen Duo test at 28 days to give you some relief.
Avatar f tn Choanal and esophageal atresia of fetus in MMI-treated and maternal hepatotoxicity in PTU-treated pregnancies are of utmost concern. Maintaining free thyroxine concentration in the upper one-third of each trimester-specific reference interval denotes success of therapy. MMI is the mainstay of the treatment of post partum hyperthyroidism, in particular during lactation." http://www.ncbi.nlm.nih.gov/pubmed/21389085 IIRC about 30% of women have thyroid enlargement during pregnancy.